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New application of Chinese medicinal composition to treatment of vascular dementia

A technology of vascular dementia and composition, which is applied in the new pharmaceutical application field of Peiyuan Tongnao pharmaceutical composition, and can solve the problems of undisclosed advanced neurocognitive dysfunction and undisclosed Peiyuan Tongnao preparation vascular dementia, etc.

Inactive Publication Date: 2011-05-25
HENAN LINGRUI PHARMA
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Problems solved by technology

[0010] However, whether the Peiyuan Tongnao preparation can treat vascular dementia is not disclosed in the prior art literature, that is to say, whether the Peiyuan Tongnao preparation can treat advanced neurocognitive dysfunction caused by cerebrovascular diseases is not disclosed in the prior art. , abstract thinking or judgment impairment (including impairment of planning, organization, procedure, and thinking ability) and long-term and short-term memory impairment and other mixed factors have a therapeutic effect on vascular dementia

Method used

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  • New application of Chinese medicinal composition to treatment of vascular dementia
  • New application of Chinese medicinal composition to treatment of vascular dementia
  • New application of Chinese medicinal composition to treatment of vascular dementia

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experiment example

[0040] Select 68 patients with mild and moderate vascular dementia who meet the diagnostic criteria, and randomly divide them into a treatment group and a control group at a ratio of 1:1. The diagnostic criteria of vascular dementia can refer to the fourth national cerebrovascular disease academic conference of the Chinese Medical Association. Meeting to determine the diagnostic criteria for vascular dementia (1995). The treatment group consisted of 34 cases, including 20 males and 14 females, with an average age of (69±8.6) years, an average course of disease of (1.2±0.6) years, 18 cases of mild dementia, 16 cases of moderate dementia, of which autosomal dominant Arterial disease (CADASIL) 7 people and amyloid cerebrovascular disease 5 people. The control group consisted of 34 cases, including 19 males and 15 females, with an average age of (67.95±9.78) years, an average disease duration of (1.23±0.41) years, 21 cases of mild dementia, 13 cases of moderate dementia, autosomal...

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Abstract

The invention discloses application of a primordial energy strengthening and brain infarction treating medicinal composition to the preparation of medicaments for treating senile vascular dementia. Compared with a control group, namely oral aniracetam, oral primordial energy strengthening and brain infarction treating capsules can effectively improve the living ability of a patient and have obvious advantages in the aspects of mini-mental state examination scale and symptom integral evaluation of traditional Chinese medical science.

Description

technical field [0001] The invention relates to a new pharmaceutical application of a Chinese patent medicine, in particular to a new pharmaceutical application of a Peiyuan Tongnao medicinal composition. Background technique [0002] Dementia is a clinical syndrome characterized by mental decline, changes in behavior and personality. Physical impairment (including planning, organization, procedure and thinking ability impairment). It is manifested that the above-mentioned abilities have declined significantly compared with the patient's own in the past, and have affected the patient's daily life, occupation and social activities. According to the etiology, dementia is mainly divided into senile dementia, vascular dementia, mixed dementia and so on. Among the dementias caused by various etiologies, senile dementia and vascular dementia account for a relatively large proportion, and the two are easily confused with each other. [0003] Alzheimer's disease (AD) and vascular...

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Application Information

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IPC IPC(8): A61K36/8965A61P9/00A61P25/28A61P9/10A61K35/32A61K35/56A61K35/62A61K35/64A61K35/586A61K35/646
Inventor 熊维政张军兵程建军肖冬华李志红武惠斌卢玉斌姜家书
Owner HENAN LINGRUI PHARMA
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