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Pharmaceutical composition for inhibiting bacteria and preparation method and application thereof

A technology of composition and medicine, which is applied in the field of pharmaceutical composition and its preparation, can solve the problems that have not been seen in the research report of Chinese herbal medicine composition, and achieve the effect of reducing harm and economic loss

Active Publication Date: 2011-05-04
中科鑫洋(江苏)生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] So far, there has not been any research report on the Chinese herbal medicine composition inhibiting the sturgeon Aeromonas veronas (Aeromonas veronii)

Method used

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  • Pharmaceutical composition for inhibiting bacteria and preparation method and application thereof
  • Pharmaceutical composition for inhibiting bacteria and preparation method and application thereof
  • Pharmaceutical composition for inhibiting bacteria and preparation method and application thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0042] The preparation method of the described pharmaceutical composition provided by the present invention comprises the following steps:

[0043] 1) Pulverizing the bulk drug and mixing in proportion; or preparing an extract containing the active ingredients of the bulk drug, and then mixing in proportion; and

[0044] 2) making pharmaceutically acceptable preparations.

[0045] Before step 1, a step of screening the proportion of the bulk drug by using Aeromonas veronii (CGMCC4274) may also be included.

[0046] The pulverization may be coarse pulverization, for example, pulverization to 80 mesh, or micronization pulverization, to 300 mesh or more.

[0047] In the above method, the extract can be alcohol extract or water extract, preferably water extract.

[0048] The pharmaceutically acceptable preparations can be solid preparations, such as granules, micronized preparations and the like.

[0049] The raw materials can be pulverized or micronized and mixed directly in p...

preparation Embodiment 1

[0055] Preparation Example 1 Preparation of Pharmaceutical Composition

[0056] 1. Prescription:

[0057] Raw materials (parts by weight): 1 part of Galla chinensis, 2 parts of Burnet elata, 8 parts of Dijincao, 4 parts of Forsythia.

[0058] 2. Process:

[0059] Use a ball mill to micronize various raw materials respectively to reach 200 meshes, and mix them in proportion.

preparation Embodiment 2

[0060] Preparation Example 2 Preparation of Pharmaceutical Composition

[0061] 1. Prescription:

[0062] Raw materials (parts by weight): 1 part of Galla chinensis, 2 parts of Burnet elata, 8 parts of Dijincao, 4 parts of Forsythia.

[0063] 2. Process:

[0064] Use a ball mill to pulverize various raw materials to achieve 300 meshes, and mix them in proportion.

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PUM

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Abstract

The invention provides a pharmaceutical composition for inhibiting bacteria and a preparation method thereof, and the pharmaceutical composition is prepared from the following pharmaceutical raw materials in parts by weight: 1 part of Chinese gall, 1-5 parts of garden burnet root, 4-12 parts of humifuse euphorbia herb and 1-8 parts of fructus forsythiae. The composition can effectively inhibit pathogenic aeromonas veronii and be further used for preventing and treating bacterial diseases of fish caused by the bacteria. The invention further provides an application of the pharmaceutical composition in the preparation of drug for inhibiting the aeromonas veronii.

Description

technical field [0001] The present invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for antibacterial, a preparation method and application thereof. Background technique [0002] Sturgeon is the oldest and most primitive ray-finned fish on the earth. It is not only a high-quality and rare fish with economic value, but also has important scientific research value. The Siberian sturgeon (Acipenser baerii) belongs to the family Acipenserdae and belongs to the genus Acipanser. It is one of the 26 existing species of sturgeon. It is mainly distributed in Siberia between the Jabi River in the west of Russia and the Kolyma River in the east. among the rivers. Siberian sturgeon has the advantages of fast growth, strong adaptability, good meat quality, and high-quality caviar. Since it was first introduced to China in 1996, its breeding volume currently ranks second in China's sturgeon breeding output. ...

Claims

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Application Information

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IPC IPC(8): A61K36/739A61P31/04A61K35/64
Inventor 马志宏罗琳李铁梁姜娜邢薇
Owner 中科鑫洋(江苏)生物技术有限公司
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