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Application of thalictrum foeniculaceum extract in preparation of medicaments for treating blood diseases

A technology of Tangsongcao silk leaf and blood diseases, which is applied to the use and preparation field of Tangsongsi silk leaf extract in the preparation of medicines for blood diseases, can solve the problems that Tangsongsi silk leaf is not recognized by people, and achieve good results. Healing effect, obvious therapeutic effect, and easy-to-obtain raw materials

Active Publication Date: 2012-07-11
SHANGHAI UPPER BIO TECH PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For a long time, Siye Tangsongcao has not been recognized by people, and it has been used as feed for cattle and sheep in large quantities and has not been developed and utilized as a Chinese herbal medicine.

Method used

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  • Application of thalictrum foeniculaceum extract in preparation of medicaments for treating blood diseases
  • Application of thalictrum foeniculaceum extract in preparation of medicaments for treating blood diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Dry the silk-leaved pine grass at a low temperature in a drying oven at 30°C to 40°C. After crushing, add water to decoct in a ratio of 1:10, decoct twice, each time for 2 to 3 hours, combine the extracts and filter with a 50-mesh sieve, and concentrate the filtrate at 60°C under reduced pressure to form a clear paste. In the stirring state, add 90% ethanol to the clear paste to make the alcohol content in the mixture to 75%, let it stand for 1-3 hours, take the supernatant and refrigerate it at 0-2°C for 48-72 hours and then cool it at 60 ℃ decompression distillation to remove ethanol, filter with a 60 mesh sieve and concentrate the filtrate under reduced pressure at 60 ℃ to obtain a purified clear paste with a concentration of 7.6 mg / ml; cool the purified clear paste to room temperature, dry it, grind it into a fine powder, and prepare get the extract.

[0030] The obtained extract is added to starch, fully mixed, granulated, dried, granulated, and compressed into 50...

Embodiment 2

[0032] Dry the silk-leaved pine grass with a drying oven at 40°C-50°C at low temperature, crush it, add water to decoct it at a ratio of 1:10, decoct 3 times, each time for 1-2 hours, combine the extracts and filter through a 30-mesh sieve , The filtrate was concentrated under reduced pressure at 50°C to a clear paste. In the state of stirring, add 90% ethanol to the clear paste to make the alcohol content in the mixture reach 70%, let it stand for 1 to 3 hours, take the supernatant and refrigerate it at 2 to 3°C for 10 to 20 hours and then cool it at 50 The ethanol was distilled off under reduced pressure at ℃. Filter with a 50-mesh sieve, and under stirring, add 90% ethanol to the clear paste to make the alcohol content in the mixture reach 85%, let stand for 1-3 hours, take the supernatant and refrigerate at 2-3°C After 20-30 hours, ethanol was distilled off under reduced pressure at 40°C. Filter with a 60-mesh sieve, and concentrate the filtrate under reduced pressure at...

Embodiment 3

[0034]Dry the silk-leaved pine grass with a drying oven at 50°C-60°C at low temperature, crush it and add water to decoct it at a ratio of 1:10, decoct 3 times, each time for 1-2 hours, combine the extracts and filter through a 40-mesh sieve , The filtrate was concentrated under reduced pressure at 50°C to a clear paste. In the state of stirring, add 90% ethanol to the clear paste to make the alcohol content in the mixture reach 75%, let it stand for 1-3 hours, take the supernatant and refrigerate it at 3-5°C for 10-20 hours and then cool it at 50 The ethanol was distilled off under reduced pressure at ℃. Filter with a 50-mesh sieve, and under stirring, add ethanol with a concentration of 90% to the clear paste to make the alcohol content in the mixture reach 80%, let it stand for 1-3 hours, take the supernatant and refrigerate at 3-5°C After 20-30 hours, ethanol was distilled off under reduced pressure at 50°C. Filter with a 60-mesh sieve, and under stirring, add 90% ethano...

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Abstract

The invention relates to an application of a plant extract, in particular to an application of a thalictrum foeniculaceum extract in the preparation of medicaments for treating blood diseases and a preparation method of the thalictrum foeniculaceum extract. The thalictrum foeniculaceum extract has the advantages that raw materials are available, pharmaceutical cost is low, dosage is little, preparation is convenient, and treatment effects on various symptoms, such as anemia, primary thrombocytopenia, secondary thrombocytopenia, aplastic anemia, leukaemia and the like, are obvious. Clinical tests show that the thalictrum foeniculaceum extract causes no obvious adverse reaction. Besides, the external application of the thalictrum foeniculaceum extract has favorable curing effects on symptoms, such as the situations that skin is injured and wound can not be healed for a long time and the like. The effective rate of treatment is more than 70%.

Description

technical field [0001] The present invention relates to the use of a plant extract, in particular to the use of a tang pine grass extract in the preparation of medicines for blood diseases and a preparation method thereof. Background technique [0002] Tangsongcao belongs to the Ranunculaceae plant, which is a unique medicinal plant in my country. It generally has anti-cancer, antibacterial and anti-inflammatory, anti-virus, blood pressure-lowering, heat-clearing and detoxifying, and analgesic effects. Currently, the recorded Tangsongcao has more than 60 species. species, mainly concentrated in the southwest region. Thalictrum foeniculaceum Bunge (Thalictrum foeniculaceum Bunge) is a special species of Tang pine grass, which was included in "Flora of China" in 2010. According to the investigation, this variety has rich wild resources and strong vitality, which is convenient for artificial large-scale planting. cultivation. For a long time, Siye Tangsongcao has not been reco...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A23L1/30A61P7/00A61P35/02A23L33/105
Inventor 王德记王光峰
Owner SHANGHAI UPPER BIO TECH PHARMA
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