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Method for preparing Xinnaokang capsules

A technology of Xinnaokang and capsules, applied in the field of medicine, can solve the problems of low bioavailability, difficult to cover up the bad taste of traditional Chinese medicine, affecting the curative effect, etc.

Inactive Publication Date: 2011-04-06
杨凌无为制药集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In solid preparations, the disintegration time of tablets is long and the bioavailability is low; powders and granules are not easy to cover the bad taste of traditional Chinese medicine; and they are easy to absorb moisture and difficult to store, which affects the curative effect and cannot meet the needs of the majority of patients.

Method used

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  • Method for preparing Xinnaokang capsules
  • Method for preparing Xinnaokang capsules
  • Method for preparing Xinnaokang capsules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] (1) Take 55g of Salvia miltiorrhiza, 35g of red peony root, 35g of Polygonum multiflorum, 35g of medlar, 35g of Pueraria lobata, 35g of Chuanxiong, 15g of safflower, 35g of Alisma, 35g of Achyranthes bidentata, 35g of earthworm, 3.5g of turmeric, 35g honey-roasted polygala, 35g Jiujie calamus, 15g fried jujube kernels, 35g deer heart powder, 15g licorice;

[0045] (2) Grind Chuanxiong, safflower, Alisma, Achyranthes bidentata, turmeric, honey-roasted polygala, calamus jiujie, fried jujube seed, and licorice described in step (1), pass through a 100-mesh sieve, and mix well ;

[0046] (3) Combine the six medicinal materials of Danshen, Radix Paeoniae Rubra, Radix Polygoni Multiflori, Lycium barbarum, Radix Puerariae, and Earthworm described in step (1), add water and decoct three times, the amount of water added for the first time is 10 times the total weight of the raw medicinal materials to be decocted , the decocting time is 3 hours, the amount of water added for the...

Embodiment 2

[0049] The preparation method of this example is the same as that of Example 1, except that the raw materials used are 105g of Salvia miltiorrhiza, 85g of Radix Paeoniae Rubra, 85g of Radix Polygoni Multiflori, 85g of Lycium barbarum, 85g of Pueraria lobata, 85g of Rhizoma Chuanxiong, 65g of safflower, Alisma 85g, Achyranthes bidentata 85g, earthworm 85g, turmeric 8.5g, honey-roasted polygala 85g, calamus jiujie 85g, fried jujube kernel 65g, deer heart powder 85g, licorice 65g.

Embodiment 3

[0051] The preparation method of this example is the same as that of Example 1, except that the raw materials used are 70g of Salvia miltiorrhiza, 50g of Radix Paeoniae Rubra, 50g of Radix Polygoni Multiflori, 50g of Lycium barbarum, 50g of Pueraria lobata, 50g of Rhizoma Chuanxiong, 30g of safflower, Alisma 50g, Achyranthes bidentata 50g, Dilong 50g, Curcuma 5g, Honey-burned Polygala 50g, Iris calamus 50g, Fried Suanzaoren 30g, Deer Heart Powder 50g, Licorice 30g.

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Abstract

The invention discloses a method for preparing Xinnaokang capsules, which comprises the following steps of: crushing nine medicinal materials, namely Sichuan lovage rhizome, red flower, rhizoma alismatis, root of bidentate achyranthes, curcumae, polygala root, irkutsk anemone rhizome, spina date seed and liquorice, screening by using a 100-mesh screen and uniformly mixing; combining six medicinalmaterials of salvia miltiorrhiza, root of common peony, prepared tuber of multiflower knotweed, fruit of Chinese wolfberry, root of kudzu vine and earthworm and adding water and decocting for three times; combining the decoction, filtering, concentrating the filtrate into thick paste with the relative density of 1.35 at the temperature of 50 DEG C, adding the screened medicinal materials into thethick paste, uniformly mixing, drying, crushing and screening by using the 100-mesh screen; and adding deer heart powder, uniformly mixing and filling into capsules and obtaining the Xinnaokang capsules. The technology is simple, and the prepared Xinnaokang capsules mask the bitter taste of the medicaments, improve the medicinal stability and bioavailability, and are beautiful in appearance, convenient to take, carry and store, and accurate in dosage.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a preparation method of Xinnaokang capsules. Background technique [0002] Coronary heart disease and angina pectoris are clinical syndromes characterized by episodic chest pain or chest discomfort caused by transient myocardial ischemia and hypoxia caused by coronary atherosclerosis and coronary artery functional changes (spasm). Coronary heart disease is also called ischemic heart disease or coronary atherosclerotic heart disease. According to its symptoms, it should belong to the category of diseases such as thoracic obstruction and heartache in traditional Chinese medicine. Cerebral arteriosclerosis is inevitable in most patients with coronary atherosclerosis. At present, there is a shortage of highly targeted therapeutic drugs, and Xinnaokang Capsules were developed under such circumstances. [0003] In solid preparations, the disintegration time of tablets ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/48A61P9/10A61K35/34A61K35/64A61K35/62
Inventor 尹子郡
Owner 杨凌无为制药集团有限公司
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