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Chinese medicinal preparation for treating persistent vegetative state (PVS)

A traditional Chinese medicine preparation and continuous technology, applied in the field of traditional Chinese medicine preparations, can solve the problems of PVS awakening and recovery, and achieve the effects of overcoming the inconvenience of decoction, improving hypoxia tolerance and fast absorption.

Active Publication Date: 2012-04-11
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hyperbaric oxygen as the main means, including nutritional support, acupuncture, electrical stimulation and other treatment methods are increasing year by year, and the awakening rate of PVS has also increased. However, the situation of awakening and rehabilitation of PVS is still severe. Finding effective methods and means is the first aid Big questions in medicine and neurology

Method used

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  • Chinese medicinal preparation for treating persistent vegetative state (PVS)
  • Chinese medicinal preparation for treating persistent vegetative state (PVS)
  • Chinese medicinal preparation for treating persistent vegetative state (PVS)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A traditional Chinese medicine preparation for treating persistent vegetative state, comprising the following components in parts by weight: 30g of astragalus, 10g of angelica, 0.05g of musk, 10g of peach kernel, 6g of calamus and 9g of angelica.

[0034] Preparation method: Extract the volatile oil of Acorus calamus, add 12 times the amount of water to take Acorus calamus, soak for 1 hour, extract the volatile oil by distillation, until the volatile oil does not increase, collect the volatile oil for later use; filter the distilled aqueous solution, and collect the filtrate in another device. Take astragalus, angelica, peach kernel, and Angelica dahurica, add water and decoct twice, add 10 times the amount of water for the first time, decoct for 1 hour, add 8 times the amount for the second time and decoct for 0.5 hours, combine the second decoction, filter, and the filtrate Combine with (1) aqueous solution, let it stand, filter, and concentrate the filtrate to a clear...

Embodiment 2

[0037] Prescription: Astragalus 20g, Angelica 12g, Musk 0.05g, Peach Kernel 10g, Shichangpu 10g, Angelica dahurica 10g.

[0038] Preparation method is the same as example 1.

[0039] As determined by high performance liquid chromatography, the content of astragaloside IV in the granules was 0.23 mg / g.

Embodiment 3

[0041] Prescription: Astragalus 20g, Angelica 12g, Musk 0.07g, Peach Kernel 12g, Shichangpu 12g, Angelica dahurica 12g.

[0042] Preparation method is the same as example 1.

[0043] As determined by high performance liquid chromatography, the content of astragaloside IV in the granules was 0.18 mg / g.

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Abstract

The invention discloses a Chinese medicinal preparation for treating persistent vegetative state (PVS), which comprises the following components in part by weight: 20 to 40 parts of astragalus, 9 to 12 parts of Chinese angelica, 0.05 to 0.1 part of musk, 8 to 12 parts of peach seed, 6 to 12 parts of grassleaf sweelflag rhizome and 9 to 12 parts of dahurian angelica root. The Chinese medicinal preparation for treating the persistent vegetative state (PVS) is vitality invigorating and aperture inducing granules and has the effects of improving the PVS marking of prior-treatment and post-treatment patients, promoting the patients to revive, improving cerebral blood supply and the hypoxia tolerant capacity of cerebral cells, exciting cerebral cortical neurons, adjusting the imbalance of intracerebral neurotransmitter dopamine and amino acid, repairing nerve cells. The pure Chinese medicinal preparation in the formulation of the granules maintains the characteristics of quick absorption and response of decoction, and overcomes the defects that the decoction is inconvenient to decoct when in use, large in dose, easy to mildew and deteriorate and the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating persistent vegetative state. Background technique [0002] Persistent vegetative state (PVS) is a special disorder of consciousness, which is characterized by the patient’s eyes open, seemingly awake, but without any conscious activity, lack of consciousness, thinking, emotion, will and other activities, and no spontaneous Language, and can not understand other people's language; lack of awareness of self and surrounding environment, unable to execute instructions; irregular sleep-wake cycle; no purposeful body movements; discontinuous eyeball chasing movements, But it cannot be fixed on a certain target. [0003] With the progress of society, the development and continuous improvement of first aid system, diagnosis and treatment technology and intensive care technology, the mortality rate of emergency patients ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/888A61P25/28A61K35/55
Inventor 奚肇庆周勤妹丰广魁
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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