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Method for preparing traditional Chinese medicinal composition for postoperative recovery in concurrent chemoradiotherapy

A composition, radiotherapy and chemotherapy technology, applied in the field of medicine, can solve problems such as electrolyte and acid-base balance disorder, gastrointestinal mucosal damage, treatment failure, etc., and achieve the effect of improving the body's immunity

Inactive Publication Date: 2011-01-19
彭军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] ②Gastrointestinal adverse reactions: Radiotherapy and chemotherapy can cause damage to the gastrointestinal mucosa. In mild cases, stomach discomfort, nausea and vomiting, and loss of appetite; Electrolyte and acid-base balance disorders, severe malnutrition, etc., thereby reducing the patient's quality of life
[0009] As mentioned above, the adverse reactions caused by radiotherapy and chemotherapy not only affect the quality of life of patients, but also make many cancer patients unable to bear their pain and give up treatment, leading to treatment failure and ultimately shortening the survival period of patients

Method used

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  • Method for preparing traditional Chinese medicinal composition for postoperative recovery in concurrent chemoradiotherapy
  • Method for preparing traditional Chinese medicinal composition for postoperative recovery in concurrent chemoradiotherapy
  • Method for preparing traditional Chinese medicinal composition for postoperative recovery in concurrent chemoradiotherapy

Examples

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Effect test

Embodiment 1

[0070] 2 parts of Astragalus, 3 parts of Codonopsis pilosula, 1 part of white peony root, 3 parts of Atractylodes macrocephala, 2 parts of epimedium, 1 part of psoralen, 3 parts of licorice;

[0071] (1) Take the above-mentioned medicinal materials in proportion, add 6 times the amount of 50% ethanol of the medicinal materials, carry out reflux extraction twice, each time for 1 hour, combine the ethanol extracts, recover the ethanol until it has no alcohol smell, and obtain the extract;

[0072] (2) Take the dregs extracted by ethanol, add 4 times the amount of water to decoct twice, each time for 1 hour, combine the decoction, and concentrate (the relative density is 1.10 when measured at 60°C);

[0073] (3) combine (1), (2) obtained ointment, concentrate under reduced pressure and become thick ointment (measure relative density at 60 ℃ and be 1.25)

[0074] (4) Add available pharmaceutical excipients to the thick paste, mix evenly, granulate, dry, and fill capsules to prepar...

Embodiment 2

[0076] 6 parts of Astragalus, 7 parts of Codonopsis, 4 parts of Paeoniae Alba, 7 parts of Atractylodes macrocephala, 6 parts of Epimedium, 4 parts of psoralen, 7 parts of licorice;

[0077] (1) Take the above-mentioned medicinal materials in proportion, add 10 times the amount of 85% ethanol of the medicinal materials to carry out reflux extraction for 4 times, each time for 3 hours, combine the ethanol extracts, recover the ethanol until it has no alcohol smell, and obtain the extract;

[0078] (2) Take the dregs extracted by ethanol, add 6 times the amount of water to decoct 4 times, each time for 3 hours, combine the decoction, and concentrate (the relative density is 1.10 when measured at 60°C);

[0079] (3) combine (1), (2) obtained ointment, concentrate under reduced pressure and become thick ointment (measure relative density at 60 ℃ and be 1.25)

[0080] (4) Add available pharmaceutical excipients to the thick paste, mix evenly, granulate, dry, and compress into tablet...

Embodiment 3

[0082] 3 parts of Astragalus, 4 parts of Codonopsis, 2 parts of Paeoniae Alba, 4 parts of Atractylodes macrocephala, 3 parts of Epimedium, 2 parts of psoralen, 4 parts of licorice;

[0083] (1) Take the above-mentioned medicinal materials in proportion, add 8 times the amount of 70% ethanol of the medicinal materials to carry out reflux extraction for 3 times, each time for 2 hours, combine the ethanol extracts, recover the ethanol until it has no alcohol smell, and obtain the extract;

[0084] (2) Take the dregs extracted by ethanol, add 5 times the amount of water to decoct 3 times, each time for 2 hours, combine the decoction, and concentrate (the relative density is 1.10 when measured at 60°C);

[0085] (3) combine (1), (2) obtained ointment, concentrate under reduced pressure and become thick ointment (measure relative density at 60 ℃ and be 1.25)

[0086] (4) Add available pharmaceutical excipients to the thick paste, mix well, granulate, sieve, and make granules.

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Abstract

The invention relates to a method for preparing a traditional Chinese medicinal composition for postoperative recovery in concurrent chemoradiotherapy. The preparation method disclosed by the invention comprises: weighing medicinal materials in proportion, and adding 50 to 85 percent ethanol in an amount which is 6 to 10 times the weight of the medicinal materials to perform refluxing extraction for 2 to 4 times and 1 to 3 hours each time, mixing ethanol extracts, reclaiming ethanol till ethanol flavor disappears completely and obtaining the extracts; decocting medicinal slag in water in an amount which is 4 to 6 times the weight of the medicinal slag for 2 to 4 times and 1 to 3 hours each time, mixing decoctions and concentrating; and mixing medicinal extracts, concentrating the extracts under reduced pressure to obtain thick extracts, and adding available pharmaceutical auxiliary materials into the thick extracts to obtain clinically usable preparations. The traditional Chinese medicinal composition is used for the postoperative recovery in the concurrent chemoradiotherapy and can improve the immunity of organisms. Years of clinical uses shows that the treatment effect of the traditional Chinese medicinal composition is remarkable.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition used for recovery after radiotherapy and chemotherapy, more specifically, it has the functions of invigorating the kidney, replenishing qi, and invigorating the spleen; it is used for the treatment of the recovery period after radiotherapy and chemotherapy, and improves the health of the human body. The invention relates to a preparation method of a traditional Chinese medicine composition with immune ability, which belongs to the technical field of medicine. Background technique [0002] At present, most of the means of treating cancer are surgery, radiotherapy, chemotherapy, etc., but radiotherapy and chemotherapy can cause various side effects such as weakness of the human body; in recent years, Chinese medicine has made gratifying achievements in the treatment of cancer. Cancer emphasizes the overall treatment plan, implements dialectical treatment, adopts t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P1/14A61P37/04
Inventor 彭军胡碧泉
Owner 彭军
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