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Aerial fog disinfectant and preparation method thereof

A disinfectant and aerosol technology, applied in the directions of disinfectant, aerosol delivery, botanical equipment and methods, etc., can solve the problems of poor use effect, inconvenience, and limited bactericidal ability of chlorhexidine acetate, To achieve the effect of good disinfection and convenient operation

Inactive Publication Date: 2010-12-15
JIANGSU AITEFU 84
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Disinfection and washing of the surface of human skin and objects has always been a topic of concern to ordinary people and professionals. The traditional method is to directly immerse the target skin or object in a disinfection solution or wipe it with a cotton swab to achieve the purpose of disinfection. The method can achieve reliable effect on relatively small disinfection area or small-volume objects, but for the disinfection work of large disinfection area or surface of objects with a certain height, it is unbearable and difficult to rely on manual smearing. high quality finish
In addition, soaking and smearing are not very convenient for use under certain conditions, especially for non-professionals. What they need is a ready-to-use disinfectant that can be used quickly and without smearing. Of course, for the operation process of medical staff There is also a need for a more convenient and practical disinfectant
In actual use, people also use manual air sprays, such as bactericidal sprays containing alcohol and chlorhexidine acetate, but the atomization effect of this dosage form is poor, and it cannot be sprayed evenly. In addition, the bactericidal ability of chlorhexidine acetate is limited. So the overall effect is not very good

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The aerosol disinfectant is filled in a pressure container and is made up of disinfectant and propellant in proportion, and the propellant propylene butane is 5.0% of the mass of the disinfectant; the mass percentage of each component in the disinfectant is: polyhexamethylene 0.1% biguanide hydrochloride, 0.1% dimethyl bisdecyl ammonium hexachloride, 1.0% propylene glycol, 5.0% ethanol, 0.05% disodium edetate, 0.05% fragrance, 93.7% deionized water.

[0025] The aerosol disinfectant is prepared in two steps. The first step is the preparation of the disinfectant solution: (1), adding accurately measured deionized water into the reactor, adding disodium edetate and stirring to raise the temperature to 40°C; ( 2), under stirring, accurately metered propylene glycol and ethanol are added into the reactor; (3), while stirring, add accurately metered polyhexamethylene biguanide hydrochloride and dimethyl bisdecyl ammonium hexachloride, so that It completely dissolves and disp...

Embodiment 2

[0027] The preparation method of this aerosol disinfectant is the same as that of Example 1. The aerosol disinfectant is filled in a 500ml, 0.45mpa pressure vessel, and is made in proportion by disinfectant and propellant, and the propellant dimethyl ether is 22.5% of the disinfectant quality. %; the mass percent of each component in the disinfectant is: polyhexamethylene biguanide hydrochloride 4.05%, dimethyl bisdecyl ammonium hexachloride 2.55%, propylene glycol 5.5%, ethanol 12.5%, ethylenediaminetetraacetic acid Disodium 0.275%, fragrance 0.525%, deionized water 74.6%.

Embodiment 3

[0029] The preparation method of this aerosol disinfectant is the same as in Example 1. The aerosol disinfectant is filled in a 1000ml, 0.6mpa pressure container, and is made up in proportion by disinfectant and propellant, and the compressed air of the propellant is 40.0% of the disinfectant quality. ; The mass percent of each component in the disinfectant is: polyhexamethylene biguanide hydrochloride 8.0%, dimethyl bisdecyl ammonium hexachloride 5.0%, propylene glycol 10.0%, ethanol 20.0%, ethylenediaminetetraacetic acid di Sodium 0.5%, Fragrance 1.0%, Deionized Water 55.5%.

[0030] The sample of Example 1 was tested by the provincial health department, sprayed and disinfected for 0.5 minutes, and the log value of killing Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, and Candida albicans artificially contaminated on the cloth sheet was greater than 3.

[0031] The sample of Example 2 is sprayed on hands and skin for 1 minute, and the logarithmic value of ...

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Abstract

The invention discloses an aerial fog disinfectant and a preparation method thereof. The preparation method mainly comprises the steps of preparing poly(hexamethylene biguanide) hydrochloride as a disinfection factor, dimethyl didecyl ammonium sulfide, propylene glycol as a solvent, ethanol, and the like into liquid disinfectant through a certain process and sealing the liquid disinfectant in a pressure-proof vessel and then filling a certain amount of propellant to ensure that the disinfectant is dispersed on the surface of an object in the form of fog. The invention is mainly used for spraying and disinfecting surfaces of hands, skin and ordinary objects to achieve convenient and rapid disinfection effect.

Description

technical field [0001] The invention relates to a disinfectant and a preparation method, in particular to an aerosol disinfectant and a preparation method. Background technique [0002] Disinfection and washing of the surface of human skin and objects has always been a topic of concern to ordinary people and professionals. The traditional method is to directly immerse the target skin or object in a disinfection solution or wipe it with a cotton swab to achieve the purpose of disinfection. The method can achieve reliable effect on relatively small disinfection area or small-volume objects, but for the disinfection work of large disinfection area or surface of objects with a certain height, it is unbearable and difficult to rely on manual smearing. High quality finish. In addition, soaking and smearing are not very convenient for use under certain conditions, especially for non-professionals. What they need is a ready-to-use disinfectant that can be used quickly and without s...

Claims

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Application Information

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IPC IPC(8): A61K31/785A61K31/14A61K9/12A61P31/04A01N47/44A01N33/12A01N25/06A01P1/00
Inventor 赵建洲
Owner JIANGSU AITEFU 84
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