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Novel purposes of ferulic acid

A ferulic acid, daily-use technology, applied to ferulic acid and its preparations, in the field of treatment of bone marrow hematopoietic dysfunction caused by low-dose radiation, to achieve the effect of high bioavailability and significant therapeutic effect

Active Publication Date: 2010-09-22
INST OF RADIATION MEDICINE ACAD OF MILITARY MEDICAL SCI OF THE PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are no reports about the use of ferulic acid in the treatment of low-dose radiation

Method used

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  • Novel purposes of ferulic acid
  • Novel purposes of ferulic acid
  • Novel purposes of ferulic acid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Embodiment 1: the preparation of tablet

[0069] According to conventional technology, ferulic acid is extracted from Siwu Tang water decoction, and conventional auxiliary materials are added to make ferulic acid tablets, which are used to treat bone marrow hematopoietic dysfunction caused by low-dose radiation. The daily dose contains ferulic acid 20mg / kg.

Embodiment 2

[0070] Embodiment 2: the preparation of capsule

[0071] According to the conventional process, ferulic acid was extracted from Siwu Decoction, and ferulic acid capsules were made by adding conventional auxiliary materials to treat bone marrow hematopoietic dysfunction caused by low-dose radiation. The daily dose contained ferulic acid 40mg / kg.

Embodiment 3

[0072] Embodiment 3: the preparation of pill

[0073] According to conventional technology, extract ferulic acid from angelica, add conventional excipients, and make ferulic acid pills to treat bone marrow hematopoietic dysfunction caused by low-dose radiation. The daily dose contains ferulic acid 80mg / kg.

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PUM

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Abstract

The invention discloses the novel purposes of a ferulic acid and a preparation thereof in curing medullary hematopoiesis dysfunction caused by low-dose radiation; the action mechanism increases visible components in peripheral blood by promoting medullary hematopoiesis, plays a significant role in curing the medullary dysfunction caused by low-dose radiation, and can provide clinical medicine with definite efficacy and high bioavailability for clinically curing low-dose radiation.

Description

field of invention [0001] The invention relates to a new application of ferulic acid, in particular to a new application of ferulic acid and its preparation in treating bone marrow hematopoietic dysfunction caused by low-dose radiation. Background technique [0002] Compared with the occurrence of large-dose exposure events or accidents, the population and probability of exposure to low-dose radiation are greater. In addition to being exposed to natural background radiation, members of the public may also suffer from frequent flight activities, medical examinations, and inappropriate living environments. , as well as occupational exposure, space activities and other ways or means, are exposed to small doses of radiation. Due to the special environment of military operations, the nature of long-term low-dose radiation exposure of officers and soldiers is often complicated. Therefore, the development of new anti-radiation damage drugs that have little or no obvious side effec...

Claims

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Application Information

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IPC IPC(8): A61K31/192A61P39/00A61P7/00
Inventor 高月马增春谭红玲洪倩梁乾德肖成荣王宇光刘明
Owner INST OF RADIATION MEDICINE ACAD OF MILITARY MEDICAL SCI OF THE PLA
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