Film coating agent for extract medicament solid preparation and preparation method thereof
A technology of film coating agent and solid preparation, which is applied in pharmaceutical formulations, medical preparations with inactive ingredients, inactive ingredients of oil/fat/wax, etc. Strong flexibility, high production efficiency, and the effect of increasing mass transfer resistance
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Embodiment 1
[0028] A kind of film coating agent for the solid preparation of extract class medicine, its component and the weight of each component are:
[0029] 50 grams of hydroxypropyl methylcellulose;
[0030] 30 grams of diethyl phthalate;
[0031] Stearic acid 20 grams.
[0032] The steps of the above-mentioned preparation method for the film coating agent of extract class medicine solid preparation are:
[0033] (1) Take by weighing 50 grams of hydroxypropyl methylcellulose, 30 grams of diethyl phthalate, and 20 grams of stearic acid;
[0034] (2) Add the weighed hydroxypropyl methylcellulose, diethyl phthalate, and stearic acid into a high-speed shearing machine, and mix the materials evenly at a speed of 350 rpm to obtain a coating agent The finished product has high production efficiency and low energy consumption.
[0035] In this embodiment, no coloring agent is used, a transparent film can be formed, and the original appearance characteristics of the product can be reflec...
Embodiment 2
[0038] A kind of film coating agent for the solid preparation of extract class medicine, its component and the weight of each component are:
[0039] 30 grams of hydroxypropyl methylcellulose;
[0040] Polyethylene glycol 5 grams;
[0041] 30 grams of stearic acid;
[0042] 35 grams of titanium dioxide.
[0043] The steps of the above-mentioned preparation method for the film coating agent of extract class medicine solid preparation are:
[0044] (1) Take by weighing 30 grams of hydroxypropyl methylcellulose, 5 grams of polyethylene glycol, 30 grams of stearic acid, and 35 grams of titanium dioxide;
[0045] (2) The hydroxypropyl methylcellulose, polyethylene glycol, stearic acid, titanium dioxide that weighed are added in the high-speed shearing machine, make material mix evenly with the speed of 500 rev / mins;
[0046] (3) Increase the speed of the high-speed shearing machine to 900 rpm, the particle size of the titanium dioxide is 10-20 μm, and the colorant is fully disp...
Embodiment 3
[0049] A kind of film coating agent for the solid preparation of extract class medicine, its component and the weight of each component are:
[0050] 60 grams of hydroxypropyl methylcellulose;
[0051] castor oil 15 grams;
[0052] Stearic acid 2 grams;
[0053] Color lake 23 grams.
[0054] The steps of the above-mentioned preparation method for the film coating agent of extract class medicine solid preparation are:
[0055] (1) Take by weighing 60 grams of hydroxypropyl methylcellulose, 15 grams of castor oil, 2 grams of stearic acid, and 23 grams of color lake;
[0056] (2) the hydroxypropyl methyl cellulose, castor oil, stearic acid, color lake that take by weighing are added in the high-speed shearing machine, make material mix homogeneously with the speed of 500 rev / mins;
[0057](3) The speed of the high-speed shearing machine is increased to 1000 rpm, the particle size of the color lake is 1-10 μm, the colorant is fully dispersed, and a finished coating agent with ...
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