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Traditional Chinese medicine composition for treating primary dysmenorrheal and preparation method thereof

A technology of primary dysmenorrhea and composition, applied in the field of traditional Chinese medicine, can solve the problems of patients with primary dysmenorrhea, blood deficiency symptoms, large dosage, etc., and achieve the solution of primary dysmenorrhea of ​​Qi stagnation and blood stasis, Smooth flow of Qi and blood and good clinical results

Active Publication Date: 2010-09-15
北京创立科创医药技术开发有限公司
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Tongjingbao granule is aimed at dysmenorrhea of ​​cold-condensed and stagnant qi. The prescription uses a large number of blood-breaking drugs, which can easily lead to blood deficiency symptoms in patients during treatment.
Tongjingling Granules are mainly aimed at dysmenorrhea caused by qi stagnation and blood stasis, but the prescription has many medicinal flavors and the dosage is large
Huahong tablets are mainly suitable for secondary dysmenorrhea, and cannot meet the needs of patients with primary dysmenorrhea

Method used

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  • Traditional Chinese medicine composition for treating primary dysmenorrheal and preparation method thereof
  • Traditional Chinese medicine composition for treating primary dysmenorrheal and preparation method thereof
  • Traditional Chinese medicine composition for treating primary dysmenorrheal and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: Granule preparation

[0029] 1. Prescription

[0030] Angelica 10kg, Chuanxiong 5kg, Rhizoma Cyperus 5kg, Wuyao 5kg

[0031] Curcuma 5kg, Yanhusuo 5kg, Sichuan Achyranthes bidentata 5kg.

[0032] Two. Method

[0033] Take the above seven flavors, take angelica, chuanxiong, vinegar cyperus, black medicine and zedoary and grind them into the coarsest powder, add 6 times the amount of water, soak for 0.5 hours, extract the volatile oil by water distillation, the extraction time is 3 hours, collect the volatile oil, and distill the aqueous solution Collect in another device; add 6 times the amount of dregs to decoct with water for 0.5 hours, filter, combine the filtrate with the above aqueous solution, and concentrate the filtrate to a relative density of 1.00-1.30 (70°C); add 6 times the amount of 60% Reflux extraction with ethanol three times, each time for 0.5 hours, filter, combine the filtrate, recover ethanol, combine with the above concentrate, conce...

Embodiment 2

[0034] Embodiment 2: Granule preparation

[0035] 1. Prescription

[0036] Angelica 20kg, Chuanxiong 15kg, Cyperus cyperi 15kg, Wuyao 10kg

[0037] Curcuma 15kg, Yanhusuo 10kg, Sichuan Achyranthes bidentata 15kg.

[0038] Two. Method

[0039]Take the above seven flavors, take angelica, chuanxiong, vinegar cyperus, black medicine and zedoary and grind them into the coarsest powder, add 10 times the amount of water, soak for 3 hours, extract the volatile oil by water distillation, the extraction time is 6 hours, collect the volatile oil, and distill the aqueous solution Collect in another device; add 10 times the amount of water to the dregs and decoct for 2 hours, filter, combine the filtrate with the above aqueous solution, and concentrate the filtrate to a relative density of 1.05-1.20 (70°C); add 10 times the amount of 75% Reflux extraction with ethanol three times, each time for 2 hours, filter, combine the filtrate, recover ethanol, combine with the above concentrate, c...

Embodiment 3

[0040] Embodiment 3: Granule preparation

[0041] 1. Prescription

[0042] Angelica 15kg, Chuanxiong 10kg, Rhizoma Cyperus 10kg, Wuyao 7kg

[0043] Curcuma 7kg Yanhusuo 7kg Sichuan Achyranthes bidentata 10kg

[0044] Two. Method

[0045] Take the above seven flavors, take angelica, chuanxiong, vinegar cyperus, black medicine and zedoary and grind them into the coarsest powder, add 8 times the amount of water, soak for 2 hours, extract the volatile oil by water distillation, the extraction time is 6 hours, collect the volatile oil, and distill the aqueous solution Collect in another device; add 8 times the amount of dregs to decoct in water for 1 hour, filter, combine the filtrate with the above aqueous solution, and concentrate the filtrate to a relative density of 1.10-1.35 (70°C); add 8 times the amount of 70% Reflux extraction with ethanol three times, each time for 1 hour, filter, combine the filtrate, recover ethanol, combine with the above concentrate, concentrate und...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating primary dysmenorrheal, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine composition for treating primary dysmenorrheal is prepared from active components comprising the following materials in parts by weight: 10-20 parts of Chinese angelica, 5-15 parts of rhizome of chuanxiong, 1-15 parts of nutgrass galingale rhizome, 5-10 parts of roots of three-nerved spicebush, 5-15 parts of curcuma zedoary, 5-10 parts of corydalis tubers and 5-15 parts of medicinal cyathula roots. The invention has the advantage that: with setting up a project for the really selected topic of the primary dysmenorrheal with more diseased symptoms and specificity shortage of therapeutic medicaments at present and making a law on the basis of the pathogenesis of main therapeutic symptoms, the invention not only takes the formation mechanism of qi depression to blood stasis into account, but also considers pathological results caused by the qi depression to blood stasis. Prescription formulation for medicine selection accords with the theories of traditional Chinese medicine, the traditional Chinese medicine composition has definite functional main treatment and symptom types of mainly treated diseases, the theories of traditional Chinese medicine science think that Chong-Ren disharmony and uterus qi and blood stases are caused by Chong and conception channel and qi-blood disharmony and pathogenic factor interference, qi and blood stases make women feel painful, which is the pathogenesis changes of dysmenorrheal, and the traditional Chinese medicine composition achieves the functions of removing stases and stopping pains through promoting flow of qi and blood circulation and has the advantages of principal and secondary treatment of diseases, definite therapeutic effect, rapid effect, favorable clinical effect and long-term and repeated application.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating primary dysmenorrhea and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. Background technique [0002] Dysmenorrhea refers to the menstrual cycle accompanied by cramping abdominal pain, which can be divided into two types: primary and secondary. Primary dysmenorrhea refers to dysmenorrhea without organic lesions in genital organs; while secondary dysmenorrhea is mostly caused by organic lesions in genital organs. [0003] According to a sample survey, primary dysmenorrhea is more likely to occur in adolescent women aged 15-25 and within 6 months to 2 years after menarche. The incidence rate is about 50%-90%, and 37%-55% of patients affect life and study. and activities. [0004] In 2004, according to a survey report by a British medical authority, 80% of women in the world have different degrees of dysmenorrhea; [0005] ...

Claims

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Application Information

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IPC IPC(8): A61K36/906A61K9/16A61P15/00
Inventor 骆春秀
Owner 北京创立科创医药技术开发有限公司
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