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Pellet for oral administration and external use and preparation process thereof

A preparation process and a technology for pellets, which are applied in the field of preparation of pellet preparations, can solve problems such as inability to be taken orally, and achieve the effects of moisturizing effect, unique anti-inflammatory effect, and good clinical treatment effect.

Active Publication Date: 2012-10-03
楚雄老拨云堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] As a traditional prescription in Yunnan, Poyun Tablet has been used for many years, and its curative effect and safety have been well verified. However, as a traditional dosage form, Poyun Tablet is generally used in combination with lozenges and eye drops, and is limited to external use. Not to be taken internally

Method used

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  • Pellet for oral administration and external use and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The micropill that can be taken orally and externally used according to the present invention is formed by the medicine combination of following components:

[0035] Calamine (calcined) 60g, borneol 20g, gentian extract 60g, myrrh (made) 3g, musk 6g, borax (calcined) 15g, mirabilite 3g, xuanming powder 3g, frankincense (made) 3g, alum (calcined) 10g. The concentration of ethanol is 40%-90%, the amount of ethanol is 45-90ml, MCC is 35g-146g, and micronized silica gel is 3.5g-14.6g.

[0036] The micropill that can be taken orally and externally of the present invention, its preparation process is:

[0037] a. Extract gentian extract: Put the rinsed gentian into the extraction tank, add 5-7 times the amount of water, soak at room temperature for 1-2 hours, heat and keep boiling for 30-60 minutes, pass through 80-200 mesh stainless steel Filter through a screen; add 4-6 times the amount of water to the filter residue, heat and keep boiling for 30-60 minutes, and filter; a...

Embodiment 2

[0045] The micropill that can be taken orally and externally used according to the present invention is formed by the medicine combination of following components:

[0046] Calamine (calcined) 20g, borneol 30g, gentian extract 35g, myrrh (made) 4g, musk 3g, borax (calcined) 20g, mirabilite 1g, xuanming powder 4g, frankincense (made) 1g, alum (calcined) 15g. The concentration of ethanol is 40%, the amount of ethanol is 90ml, MCC is 35g, and micronized silica gel is 14.6g.

[0047] The micropill that can be taken orally and externally of the present invention, its preparation process is:

[0048] a. extract gentian extract: put the gentian after rinsing into the extraction tank, add 5 times the amount of water, soak for 1 hour at room temperature, heat and keep boiling for 60 minutes, filter through an 80-mesh stainless steel screen; add 4 Double the amount of water, heat and keep boiling for 60 minutes, filter; add 3 times the amount of water to the filter residue, heat and k...

Embodiment 3

[0056] The micropill that can be taken orally and externally used according to the present invention is formed by the medicine combination of following components:

[0057] Calamine (calcined) 90g, borneol 6g, gentian extract 90g, myrrh (made) 1g, musk 8g, borax (calcined) 4g, mirabilite 4g, xuanming powder 1g, frankincense (made) 4g, alum (calcined) 5g. The concentration of ethanol is 90%, the amount of ethanol is 45ml, MCC is 146g, and micronized silica gel is 3.5g.

[0058] The micropill that can be taken orally and externally of the present invention, its preparation process is:

[0059] a. extract gentian extract: put the gentian extract after rinsing into the extraction tank, add 5 times the amount of water, soak for 2 hours at room temperature, heat and keep boiling for 30 minutes, filter through a 200-mesh stainless steel screen; add 6 Double the amount of water, heat and keep boiling for 30 minutes, filter; add 5 times the amount of water to the filter residue, heat...

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Abstract

The invention provides a pellet for oral administration and external use, and relates to a pharmaceutical preparation, in particular to a pellet preparation for both oral administration and external use. The invention also relates to a preparation method of the pellet preparation. The pellet preparation is prepared by the combination of the following pharmaceutical components: 20-90g of calamine (calcined), 6-30g of borneol, 35-90g of gentian extract, 1-4g of myrrh (prepared), 3-8g of musk, 4-20g of borax (calcined), 1-4g of mirabilite, 1-4g of natrii sulfas exsiccatus, 1-4g of mastic (prepared), 5-15g of alumen (calcined), 40-90% ethanol, 35-146g of MCC and 3.5-14.6g of micronized silica gel. The pellet preparation is a Chinese patent preparation for both oral administration and externaluse, is generally for external use in ophthalmology, and has curative effects of improving symptoms and traditional Chinese medical syndromes on viral keratitis (punctate keratitis), pterygium, acuteand chronic catarrhal conjuntivitis and trachoma, thereby being an effective and safe traditional Chinese medicine preparation.

Description

technical field [0001] The invention relates to a pharmaceutical preparation, in particular to a pellet preparation which can be taken internally or externally, and also relates to a preparation method of the pellet preparation. Background technique [0002] As a traditional prescription in Yunnan, Poyun Tablet has been used for many years, and its curative effect and safety have been well verified. However, as a traditional dosage form, Poyun Tablet is generally used in combination with lozenges and eye drops, and is limited to external use. Not to be taken internally. Only external use is used for eye diseases, the onset is slow, and no fundamental treatment can be obtained. Generally, doctors add other internal medicines during treatment, so as to continue the therapeutic effect. Contents of the invention [0003] The purpose of the present invention is to overcome the defects of the prior art, and to provide a pellet preparation that can be taken orally or externally....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/515A61K9/16A61P27/02A61P31/12A61P31/22A61P1/02A61P11/04A61P27/12A61K31/045A61K33/04A61K33/06A61K33/22A61K33/30A61K35/55
Inventor 殷亦坚曲颖邝云仙
Owner 楚雄老拨云堂药业有限公司
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