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Medicine for resisting insomnia and preparation method thereof

A technology of medicine and Chinese herbal medicine, applied in the field of effective medicine for treating insomnia and its preparation, can solve the problems of slow onset time, short curative effect time, unclear active ingredients, etc., and achieve the effect of convenient taking and definite curative effect

Inactive Publication Date: 2012-06-13
辽宁省中医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] In summary, it can be seen that there are many medicines for treating insomnia in traditional Chinese medicine, but most of them are pills or pills, with complex prescriptions, unclear active ingredients, large dosage, slow onset time, and short curative effect time. Sleeping traditional Chinese medicine with fast effect and long curative effect is of great significance

Method used

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  • Medicine for resisting insomnia and preparation method thereof
  • Medicine for resisting insomnia and preparation method thereof
  • Medicine for resisting insomnia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] 900 grams of Salvia miltiorrhiza, 900 grams of Corydalis Corydalis, 1800 grams of Jujube Seed, and 900 grams of Schisandra chinensis were made into 1000 capsules. Its concrete preparation process is as follows:

[0047]Extract danshen with water twice, 1 hour each time, filter, combine the filtrates, concentrate to a clear paste with a relative density of 1.00, put it on the styrene-type macroporous adsorption resin of HPD600, elute with 5 times the column volume of water, discard Remove the eluate from water, continue to elute with 8 times the amount of 60% ethanol, collect the eluate, and dry it under reduced pressure; Corydalis Corydalis is broken into powder, extracted with 70% ethanol for 3 times, each time for 3 hours, filtered, Combine the filtrates, recover ethanol to a clear paste with a relative density of 1.12, add an appropriate amount of water, put it on the styrene-type macroporous adsorption resin, elute with 5 times the column volume of water, discard th...

Embodiment 2

[0064] 900 grams of Salvia miltiorrhiza, 900 grams of Corydalis Corydalis, 1800 grams of Jujube Seed, and 900 grams of Schisandra chinensis were made into 1000 capsules. Its concrete preparation process is as follows:

[0065] Extract Danshen with water 3 times, each time for 0.5 hours, filter, combine the filtrates, concentrate to a clear paste with a relative density of 1.08, put it on the styrene-type macroporous adsorption resin of HPD450, elute with 4 times the column volume of water, discard Remove the eluate from water, continue to elute with 5 times the amount of 40% ethanol, collect the eluate, and dry it under reduced pressure; Corydalis Corydalis is crushed into powder, extracted twice with 50% ethanol, each time for 1.5 hours, filtered, Combine the filtrates, recover ethanol to a clear paste with a relative density of 1.02, add an appropriate amount of water, put it on the styrene-type macroporous adsorption resin, elute with 3 times the column volume of water, dis...

Embodiment 3

[0084] 800 grams of Danshen, 800 grams of Corydalis Corydalis, 1600 grams of Jujube Seed, and 800 grams of Schisandra chinensis were made into 1000 capsules. Its concrete preparation process is as follows:

[0085] Extract with water twice, 1.0 hour each time, filter, combine the filtrates, concentrate to a clear paste with a relative density of 1.02, put it on the AB8 macroporous adsorption resin, elute with 3 times the column volume of water, and discard the water for elution solution, continue to elute with 6 times the amount of 60% ethanol, collect the eluate, and dry it under reduced pressure; Corydalis is crushed into powder, and extracted 3 times with 60% ethanol, each time for 1.5 hours, filtered, combined filtrate, and recovered Ethanol to a clear paste with a relative density of 1.02, add an appropriate amount of water, put it on a styrene-type macroporous adsorption resin, elute with 5 times the column volume of water, discard the water eluent, and continue to elute...

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Abstract

The invention relates to a medicine for resisting insomnia, which is characterized by being prepared from the following Chinese herbal medicines in parts by weight: 10-15 parts of radix salviae miltiorrhizae, 10-15 parts of corydalis tuber, 15-30 parts of wild or spiny jujuba seed and 10-15 parts of schisandra fruit. The invention has the functions of nourishing the heart, soothing the nerves andsuppressing the nerve centre, has definite curative effect, is safe and effective and is convenient for patients to take.

Description

technical field [0001] The invention relates to a pure traditional Chinese medicine preparation, and in particular provides an effective medicine for treating insomnia and a preparation method thereof. Background technique [0002] Insomnia, traditional Chinese medicine calls it "insomnia", that is, inability to fall asleep, or intermittent or dreamy, early awakening, or even insomnia all night, generally sleeping less than 6 hours a day for more than 2 consecutive weeks, it is diagnosed as insomnia. In mild cases, dizziness, fatigue, lack of energy, reduced learning and work efficiency. In severe cases, head fullness and headache, palpitation, upset, or irritability, dry mouth, bitter taste, loss of appetite, irregular stool and other systemic symptoms appear, and the patient is very painful. Studies in the past five years have found that there are many pathogenic factors of this disease , involving a variety of physical or mental illnesses. According to statistics in 199...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/725A61K9/48A61P25/20
Inventor 尤献民王玉琢贾东邹桂欣杜佳林姜鸿向绍杰王光函张颖杨明李伟博刘宣
Owner 辽宁省中医药研究院
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