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Quality control method for Chinese medicinal capsule for treating anemofrigid cold

A quality control method and technology of traditional Chinese medicine capsules, which are applied in the quality control of traditional Chinese medicine capsules and the field of traditional Chinese medicine compositions for treating colds, and can solve problems such as difficulty in ensuring the curative effect and quality stability of medicines

Active Publication Date: 2009-11-11
BEIJING ASIA EAST BIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although Chinese patent medicines have few side effects and can achieve the goal of treating both symptoms and root causes, it is difficult to ensure the stability of the efficacy and quality of medicines due to the one-sidedness of quality control methods

Method used

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  • Quality control method for Chinese medicinal capsule for treating anemofrigid cold
  • Quality control method for Chinese medicinal capsule for treating anemofrigid cold
  • Quality control method for Chinese medicinal capsule for treating anemofrigid cold

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0227] Nepeta panicle 800g, Mint 75g, Fangfeng 500g, Bupleurum 400g, Perilla leaf 200g, Pueraria 150g, Campanulaceae 300g, Bitter almond 400g, Angelica dahurica 125g, Kudiding 300g, Reed root 400g.

[0228] For the above eleven flavors, add 10 times the amount of water to the ears of Nepeta chinensis, extract the volatile oil for 4 hours, collect the distilled aqueous solution in another device, add water to decoct the medicinal residues and other ten flavors such as Fangfeng twice, and add water to 8 times, 6 Double the amount, 1.5 hours each time, combine the decoction, filter, combine the filtrate with the above aqueous solution, concentrate to a relative density of 1.30 (50°C), dry, grind into fine powder, sieve, add the above nepeta panicle volatile oil, and mix well , put into capsules, make 1000 capsules, and get ready.

[0229] (1) Take 5g of the content of this product, add petroleum ether (30-60°C) 20ml, soak for 1 hour, filter, take the filtrate and evaporate to 0.5...

Embodiment 2

[0239] Nepeta panicle 800g, mulberry leaves 75g, Fangfeng 500g, Bupleurum 400g, Notopterygium 200g, Pueraria 150g, Bellflower 300g, Bitter almond 400g, Angelica dahurica 125g, Kudiding 300g, Reed rhizome 400g.

[0240] For the above eleven flavors, take Nepeta ear, mint, and perilla leaves, add 10 times the amount of water, extract the volatile oil for 4 hours, collect the distilled aqueous solution in another device, add water to decoct the medicinal residues and other eight flavors such as Fangfeng twice, and add water respectively. 8 times the amount, 6 times the amount, 1.5 hours each time, combine the decoction, filter, combine the filtrate with the above aqueous solution, concentrate to a relative density of 1.30 (50°C), dry, grind into fine powder, sieve, add the above The mustard ear and other volatile oils are mixed evenly, put into capsules, and made into 1000 capsules, and the product is ready.

[0241] (1) Take 5g of the content of this product, add petroleum ether...

Embodiment 3

[0248] Nepeta panicle 800g, Arctium 75g, Fangfeng 500g, Bupleurum 400g, Ligusticum 200g, Pueraria 150g, Campanulaceae 300g, Bitter almond 400g, Angelica dahurica 125g, Kudiding 300g, Bamboo leaves 400g.

[0249] For the above eleven flavors, add 10 times the amount of water to the ears of Nepeta chinensis, extract the volatile oil for 4 hours, collect the distilled aqueous solution in another device, add water to decoct the medicinal residues and other ten flavors such as Fangfeng twice, and add water to 8 times, 6 Double the amount, 1.5 hours each time, combine the decoction, filter, combine the filtrate with the above aqueous solution, concentrate to a relative density of 1.30 (50°C), dry, grind into fine powder, sieve, add the above nepeta panicle volatile oil, and mix well , put into capsules, make 1000 capsules, and get ready.

[0250] (1) Determination according to high-performance liquid chromatography: chromatographic conditions and system suitability test, using octad...

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Abstract

The invention provides a quality control method for a Chinese medicinal capsule for treating anemofrigid cold. The Chinese medicinal capsule is prepared from bulk drugs such as schizonepeta spike, mulberry leaf, divaricate saposhnikovia root, radix bupleuri, incised notopterygium rhizome, kudzuvine root, platycodon root, bitter apricot seed, dahurian angelica root, bunge corydalis, reed rhizome and the like, and can be prepared by adding accessories according to a conventional process. The quality control method for the Chinese medicinal composition comprises thin layer qualitative check for the schizonepeta spike, the kudzuvine root, the bunge corydalis, the radix bupleuri, the divaricate saposhnikovia root and the platycodon root, and quantitative detection for puerarin, cimiside and 4'-O-glucopyranosyl-5-O-methylvisamminol. The Chinese medicinal composition has obvious effect of treating the anemofrigid cold.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating colds, in particular to a quality control method of traditional Chinese medicine capsules for treating wind-cold colds, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] Cold is a common exogenous disease in four seasons, especially in winter and spring. Many families have Chinese patent medicines for treating colds. Some people have taken a lot of medicines after suffering from colds, but the symptoms have not been relieved. The key is that there is no medicine based on syndrome differentiation. Chinese medicine believes that colds can generally be divided into two categories: wind-cold cold and wind-heat cold. The etiology and pathogenesis, symptoms, treatment principles and medication of these two kinds of colds are very different. [0003] Traditional Chinese medicine often uses ephedra, Nepeta, Fangfeng, Su Ye and oth...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K36/736A61K9/48A61P31/00A61P29/00A61P11/00G01N30/90G01N30/26G01N30/36
Inventor 付立家付建家
Owner BEIJING ASIA EAST BIO PHARMA CO LTD
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