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Implantable shunt or catheter enabling gradual delivery of therapeutic agents

A technology of shunts and therapeutic agents, which can be applied to medical devices, wound drainage devices, and other medical devices, and can solve problems such as infection, obstruction or blockage of the inflow end, and failure of the system to release overpressure, etc.

Inactive Publication Date: 2009-08-19
WYETH LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] A problem encountered with the implantation of such catheters and shunts is that the inflow end of the ventricular catheter may become obstructed or blocked by ingrowth of choroid tissue
This prevented the system from releasing overpressure and required surgery to remove it without tearing brain tissue or causing bleeding
[0006] Another problem is infection

Method used

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  • Implantable shunt or catheter enabling gradual delivery of therapeutic agents
  • Implantable shunt or catheter enabling gradual delivery of therapeutic agents
  • Implantable shunt or catheter enabling gradual delivery of therapeutic agents

Examples

Experimental program
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Embodiment Construction

[0034] The present invention relates to catheters or shunts for implantation in a patient as part of a shunt system that drains fluid between different regions of the patient's body. A shunt system used to treat hydrocephalus provides an example. However, the implantable catheter / shunt of the present invention may be used in other drainage or similar applications.

[0035] The implantable catheter / shunt of the present invention is particularly useful where it is desired to deliver a therapeutic agent, drug, or similar useful substance to the catheter / shunt adjacent to the inner and / or outer surface and / or within the catheter / shunt In the use of the location in the cavity. For example, the catheter / shunt of the present invention can be used to gradually release one or more therapeutic agents that minimize the risk of blockage or obstruction of the lumen of the catheter / shunt or minimize the risk of infection. Of course, the catheter / shunt of the present invention may also be ...

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PUM

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Abstract

An implantable catheter or shunt (24) for draining fluid from a body cavity. The catheter or shunt body has a wall structure (28) that carries one or more therapeutic agents (26) in a manner enabling release of the therapeutic agent from the wall structure in situ after surgical implantation of the catheter or shunt body. The therapeutic agent can be gradually released over time to prevent infection, inhibit tissue ingrowths, and / or provide some other desired medicinal purpose. As an example, the therapeutic agent can be rapamycin or an mTOR inhibitor. According to some contemplated embodiments of the present invention, the therapeutic agent carried by the catheter / shunt is rechargeable or refillable in situ so that the therapeutic agent can be gradually released from the catheter / shunt over the expected useful life of the catheter / shunt.

Description

technical field [0001] The present invention relates generally to surgical devices, such as implantable catheters and shunts, used for draining fluid between different regions in the human body, and more particularly to making blockage and obstruction and and / or catheters and shunts that minimize the risk of infection. Background technique [0002] Shunts and catheters have been used in surgical applications to control the flow of bodily fluids between various regions of the body. For example, implantable shunt systems are used in the treatment of hydrocephalus to overcome or control the lack of free circulation and / or absorption of cerebrospinal fluid within the human brain. [0003] Hydrocephalus is a neurological disorder caused by abnormal accumulation of cerebrospinal fluid in the ventricles or cavities of the brain. Cerebrospinal fluid surrounds the brain and spinal cord and circulates through the ventricular system to provide cushioning for the brain and spinal cord...

Claims

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Application Information

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IPC IPC(8): A61M27/00A61M31/00A61F2/82
CPCA61M27/008A61M27/006A61M27/00A61M31/002A61M31/00A61P43/00
Inventor D·L·德拉古恩J·M·科亨
Owner WYETH LLC
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