Partition method for crossing-overlapped chromosome
A chromosome and intersection technology, applied in the segmentation of overlapping and overlapping chromosomes, can solve the problems of segmentation errors, misjudgment of concave points, and consumption, and achieve the effect of high accuracy and efficiency improvement.
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Embodiment 1
[0042] The technical solution in this embodiment is to segment cross-overlapping chromosomes based on the measurement of the length of normal line segments. Among them, specifically include the following steps:
[0043] Step 1, the overlapping area of the first chromosome and the second chromosome is the central area; draw a line segment along the skeleton direction of the first chromosome in the central area according to the received line drawing instruction, and the length of the line segment is greater than the width of the second chromosome. Before performing this step, it is generally necessary to perform some preprocessing and edge detection on the images of crossed and overlapping chromosomes. This step is the same as the preprocessing and edge detection steps of chromosome analysis in the prior art. Firstly, the chromosome image is preprocessed by removing miscellaneous information, noise and increasing image contrast; then, edge detection is performed on the chromos...
Embodiment 2
[0063] The technical solution in this embodiment is to segment cross-overlapping chromosomes based on the length measurement of parallel line segments. Among them, specifically include the following steps:
[0064] Step 1, the overlapping area of the first chromosome and the second chromosome is the central area; draw a line segment in the central area along the skeleton direction of the first chromosome after receiving a line drawing instruction, and the length of the line segment is greater than the width of the second chromosome. Similarly, before performing this step, it is necessary to perform preprocessing on the chromosome image to remove miscellaneous information, noise points and increase image contrast; then use the differential operator to perform edge detection on the chromosome image.
[0065] Step 2, calculate the slope of the line segment and its normal slope, and obtain the calculation result.
[0066] The above two steps are the same as the corresponding st...
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