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Extraction method of arca extract freeze-drying powder

An extraction method and extraction technology, which is applied in the field of extraction of cockles extract freeze-dried powder, can solve the problems that have not been reported, and achieve the effect of simple and effective extraction process, prolonging the survival period and improving the quality of life

Inactive Publication Date: 2009-04-29
青岛海生肿瘤医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] So far, there have been no reports abroad about extracting effective pharmaceutical ingredients from marine cockles

Method used

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  • Extraction method of arca extract freeze-drying powder
  • Extraction method of arca extract freeze-drying powder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take 400Kg of fresh cockles, wash them repeatedly with drinking water until there is no mud on the surface of the shells, and then wash them three times with purified water, remove the shells and take soft tissues, wash them with purified water until there is no blood stain, drain the water to get the net material and weigh it. Crush with a masher, the particle size is 0.3cm, add purified water at a weight ratio (w / w) of 1:1.5, stir and extract with a mixer at a slow speed (60r / min) for 4 hours at 0-10°C, the extraction device GQ105 high-speed tube Type centrifuge (20000r / min) centrifugal deslagging, carry out freeze-drying, obtain freeze-dried powder raw material, mix evenly, vacuum-pack, put in refrigerator, the result is as follows:

[0027] Table 1

[0028]

[0029]

Embodiment 2-3

[0031] The manufacturing steps of Example 2-3 are the same as those of Example 1, except that the extraction process is listed in Table 1 above.

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Abstract

The invention relates to a method for extracting a clam extract freeze-dried powder. The method is characterized by comprising the following steps: cleaning: fresh marine organism clams are cleaned to remove sludge, shells are removed, soft bodies are taken out and cleaned until no bloodiness is left and then drained, thus obtaining a clean material; mashing: particle size is between 0.2cm and 0.4cm; extracting: the clean material mashed is mixed with water by a ratio of 1:1 to 1:2 in an extraction plant for extraction for 2 hours to 6 hours at temperature between 0 DEG C and 10 DEG C, separation, centrifugation and deslagging are conducted, thus obtaining a centrifugate; and freeze-drying: the clam extract freeze-dried powder is obtained through pre-freezing and first phase and second phase of sublimation. The extraction method is simple and effective, has effective components with the high content of bioactive proteins and is used for producing clam extract enteric-coated capsules to treat early, intermediate stage and terminal cancer patients such as lung cancer, liver cancer, renal carcinoma, carcinoma ventriculi, cervical carcinoma patients and the like.

Description

technical field [0001] The invention relates to the field of marine organism extraction, in particular to a method for extracting clam extract freeze-dried powder of marine organism cockle extract. Background technique [0002] The ocean covers 71% of the earth's surface area, and the total volume of seawater accounts for 97% of the total water volume of the earth. The effective area of ​​the unused ocean and coast is 5 to 10 times larger than that of the land. There are a lot of marine life in the ocean, and the resources are extremely rich. Moreover, marine organisms survive and develop in a specific environment of high salinity in the ocean. Compared with terrestrial organisms, they have unique characteristics and pharmacological activities. They are currently less polluted biological resources in the world and are new resources for obtaining biologically active substances. The development of marine biological drugs is more and more important. It has attracted more and mo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/56A61P35/00A61K35/618
Inventor 韩彦弢王春波陈守国
Owner 青岛海生肿瘤医院
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