Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Tissue-adhesive materials

A tissue and adhesive sheet technology, applied in the field of flexible sheets, can solve the problems of difficult operation, expensive, time-consuming, etc., and achieve the effects of improved flexibility, good adhesion, and excellent stickiness

Active Publication Date: 2013-01-23
TISSUEMED LTD
View PDF0 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such energy sources can be expensive and difficult to handle, especially within the confines of an operating room or similar environment
Furthermore, using external energy for attachment can be time-consuming and (in some cases) requires very careful judgment by the surgeon to assess when enough energy has been delivered to achieve attachment without damaging the underlying tissue energy of
[0006] A disadvantage of sheet-type products for the above applications is that they may lack the softness that is necessary or desirable for many applications

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Tissue-adhesive materials
  • Tissue-adhesive materials

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0021] abbreviation

[0022] AAc acrylic acid

[0023] AIBN azoisobutyronitrile

[0024] DCC Dicyclohexylcarbodiimide

[0025] DCM dichloromethane

[0026] DCU Dicyclohexylurea

[0027] DMF Dimethylformamide

[0028] DMSO Dimethyl Sulfoxide

[0029] DPBS Dulbecco's Phosphate Buffered Saline

[0030] ENT Ear, Nose and Throat

[0031] HPC Hydroxypropyl Cellulose

[0032] IPA isopropyl alcohol

[0033] m n Number average molecular weight

[0034] m w Weight average molecular weight

[0035]MeOH Methanol

[0036] NHS N-Hydroxysuccinimide

[0037] NVP N-Vinylpyrrolidone

[0038] PEG polyethylene glycol

[0039] PLG DL-lactide-glycolide copolymer

[0040] (poly(DL-lactide-co-glycolide))

[0041] Poly(VP-AAc) Copolymer of Vinylpyrrolidone and Acrylic Acid

[0042] Copolymer of poly(VP-AAc(NHS)) vinylpyrrolidone and NHS acrylate

[0043] Poly(VP-AAc-AAc(NHS)) vinylpyrrolidone, acrylic acid and NHS acrylate

[0044] ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to View More

Abstract

A multi-lamellar tissue-adhesive sheet comprises a structural layer or laminate conjoined to a tissue-contacting layer. The structural layer or laminate comprises one or more synthetic polymers having film-forming properties, and the tissue- contacting layer of material contains tissue-reactive groups. The synthetic polymers having film-forming properties are preferably biodegradable polyesters, and the tissue-reactive groups are most preferably NHS-ester groups.

Description

field of invention [0001] The present invention relates to a flexible sheet suitable for use as a tissue adhesive sealant intended for topical application to internal and external surfaces of the body for therapeutic purposes. The invention also relates to methods for preparing such tablets and methods of using such tablets. In particular, the present invention relates to self-adhesive, biocompatible, and hydratable polymer sheets that can be used for therapeutic purposes such as wound healing, bonding, sealing, and strengthening weakened tissues, and for delivering therapeutic agent, and the invention relates to methods for preparing such tablets and methods of using such tablets. The invention further relates to an implantable medical device coated with a material similar to that of said sheet. Background of the invention [0002] The use of materials that adhere to biological tissue is of considerable interest in many surgical or other therapeutic applications, for exam...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L31/04A61L31/10A61L31/14C08L39/06
Inventor 格莱姆・凯特维尔大卫・曼德勒大卫・弗特恩伊恩・汤普森黛安・莫里斯
Owner TISSUEMED LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com