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New use of loquat flower and its extract

The technology of extract and loquat flower is applied in the field of preparation of medicines for treating pharyngitis, which can solve the problems of complex and diverse clinical manifestations, and achieve the effect of clear medicinal effect and strong controllability.

Active Publication Date: 2009-02-18
CHENGDU QINGSHAN LIKANG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] In summary, although it is disclosed that loquat flower has antitussive, expectorant, antibacterial, and anti-inflammatory effects, but due to the complex and diverse etiology, pathogenesis, and clinical manifestations of pharyngitis, it is used for antitussive, expectorant, and antibacterial effects. Drugs may not necessarily be used to treat pharyngitis, there is no corresponding relationship between them

Method used

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  • New use of loquat flower and its extract
  • New use of loquat flower and its extract
  • New use of loquat flower and its extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 The preparation of medicine of the present invention

[0027] Weigh about 100g of dried loquat flower, first use 90% ethanol as the extraction solvent, the solid-to-liquid ratio is 1:6, and the temperature is 90°C, extract until no ursolic acid and oleanolic acid are detected; then use 40% ethanol as the extraction solvent Extraction solvent, solid-to-liquid ratio 1:12, temperature 90°C, extract until no total flavonoids are detected. After extraction, the extract is filtered, concentrated to a specific gravity of about 1.22, and dried to obtain the loquat flower extract.

Embodiment 2

[0028] Embodiment 2 Preparation of the extract of the present invention

[0029] Weigh about 100g of dried loquat flowers, first use 80% ethanol as the extraction solvent, the solid-to-liquid ratio is 1:12, and the temperature is 100°C, extract until no ursolic acid and oleanolic acid are detected; then use 40% ethanol as the extraction solvent Extraction solvent, solid-to-liquid ratio 1:6, temperature 100°C, extract until no total flavonoids are detected. After extraction, the extract is filtered, concentrated to a specific gravity of about 1.45, and dried to obtain the loquat flower extract.

Embodiment 3

[0030] Embodiment 3 Preparation of the extract of the present invention

[0031] Weigh about 100g of dried loquat flower, first use 95% ethanol as the extraction solvent, the solid-to-liquid ratio is 1:8, and the temperature is 60°C, extract until no ursolic acid and oleanolic acid are detected; the residue is then used as the extraction solvent with 65% ethanol Extraction solvent, solid-to-liquid ratio 1:12, temperature 80°C, extract until no total flavonoids are detected. After extraction, the extract is filtered, concentrated to a specific gravity of about 1.05, and dried to obtain the loquat flower extract.

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PUM

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Abstract

The invention provides application of Eriobotrya japonica Lindl and extract thereof to the preparation of medicines for treating pharyngitis. The invention also provides a pharmaceutical composition for treating pharyngitis and a preparation method thereof. The invention uses the Eriobotrya japonica Lindl and the extract thereof to treat pharyngitis, in particular to chronic pharyngitis, with definite drug effect. With the pharmaceutical composition prepared by the method, the drug effect is obviously superior to the prior medicine, the controllability is strong, and a new choice for clinic is provided.

Description

technical field [0001] The present invention relates to the new application of loquat flower Eriobotrya japonica Lindl and its extract, specifically, the application in preparing medicine for treating pharyngitis. Background technique [0002] Loquat, scientific name Eriobotrya japonica (Thunb.) Lindl, Rosaceae. The fruit, seed, flower, leaf, skin and root of loquat can be used as medicine. Loquat flower has the effect of treating common cold, coughing with phlegm and blood, moistening throat and relieving cough (see Jiangsu New Medical College edit, "Chinese Medicine Encyclopedia" first edition volume 1977, Shanghai Science and Technology Press, page 1250). Application number: 200610022453.X, title of invention: a loquat flower extract, a composition containing the extract and its application. The present invention relates to a loquat flower extract, which is made of the flower, flower bud and receptacle of loquat Eriobotrya japonica Lindl as raw materials , prepared by a...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P11/04A61K133/00
Inventor 张宏张晓喻陶宗娅崔盛黄洪
Owner CHENGDU QINGSHAN LIKANG PHARMA CO LTD
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