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Capsules for treating peptic ulcer and preparation method thereof

The technology of capsules and sea octopus is applied in the field of capsules for treating peptic ulcers and the field of preparation thereof, and achieves the effects of no toxic side effects, short course of treatment and clear mechanism.

Active Publication Date: 2008-12-24
LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, peptic ulcer of spleen and stomach deficiency and cold type is a common disease. The symptoms of this disease include epigastric pain, warm and pressing, severe pain when hungry, or pain at night, pantothenic acid and bitter vomiting. Treatment drugs that are particularly effective or have been patented

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A traditional Chinese medicine compound preparation for treating peptic ulcer, the raw material formula is as follows:

[0026] Astragalus 100g Paeoniae Alba 100g Angelica 60g

[0027]Guizhi 60 Sea Cuttlefish 60g Fritillaria 60g

[0028] Yinxingcao 60g Coptidis 10g Licorice 60g

[0029] Preparation:

[0030] Pulverize sea octopus into fine powder; add 10 times the amount of water to angelica, cinnamon twigs, and yinxingcao, soak for 12 hours, steam distill to extract the volatile oil for 6 hours, collect the distilled aqueous solution in another device, and set aside; use 10 times the amount of β for volatile oil -Cyclodextrin, use saturated aqueous solution method to clathrate at 50°C for 2 hours, refrigerate, filter with suction, dry below 40°C, grind finely, and set aside; distilled medicinal residues and astragalus plus 10 times the amount of water are decocted 3 times, each 2 hours each time, filter the decoction, and use the filtrate for later use; use 8 times ...

Embodiment 2

[0032] A traditional Chinese medicine compound preparation for treating peptic ulcer, the raw material formula is as follows:

[0033] Astragalus 300g White peony 300g Angelica 120g

[0034] Guizhi 120 Sea Cuttlefish 120g Fritillaria 150g

[0035] Yinxingcao 150g Coptidis 60g Licorice 120g

[0036] Preparation:

[0037] Pulverize squid and octopus into fine powder; add 12 times the amount of water to angelica, cassia twigs, and yinxingcao, soak for 12 hours, steam distill to extract the volatile oil for 8 hours, collect the distilled aqueous solution in another device, and set aside; use 20 times the amount of β for volatile oil -Cyclodextrin, using saturated aqueous solution method for inclusion at 30°C for 3 hours, refrigerated, suction filtered, dried below 40°C, finely ground, and set aside; the distilled medicinal dregs and astragalus plus 8 times the amount of water were decocted 3 times, each 2 hours each time, filter the decoction, and use the filtrate for later use...

Embodiment 3

[0039] A traditional Chinese medicine compound preparation for treating peptic ulcer, the raw material formula is as follows:

[0040] Astragalus 150g White peony 150g Angelica 150g

[0041] Guizhi 120 Sea Cuttlefish 150g Fritillaria 120g

[0042] Yinxingcao 120g Coptidis 60g Licorice 120g

[0043] Preparation:

[0044] Pulverize squid and octopus into fine powder; add 14 times the amount of water to angelica, cinnamon twigs, and yinxingcao, soak for 12 hours, steam distill to extract the volatile oil for 10 hours, collect the distilled aqueous solution in another device, and set aside; use 15 times the amount of β for volatile oil -Cyclodextrin, use saturated aqueous solution method for inclusion at 40°C for 1 hour, refrigerate, suction filter, dry below 40°C, grind finely, and set aside; distilled medicinal residues and astragalus plus 15 times the amount of water are decocted twice, each 2 hours each time, filter the decoction, and use the filtrate for later use; use 10 ...

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PUM

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Abstract

The invention discloses a capsule for remedying peptic ulcer and a preparation method thereof. The capsule takes Chinese medicinal plants of astragalus, white peony root, angelica, cassia twig, cuttlebone, fritillary bulb, siphonostegia chinensis, coptis chinensis, liquorices and so on as raw materials. The cuttlebone is crushed. The volatile oil is extracted from angelica, cassia twig and siphonostegia chinensis. The volatile oil is packed by beta-cylodextrin. The astragalus is extracted by water. The white peony root, fritillary bulb, coptis chinensis and liquorices are extracted by alcohol. The extracting solutions is made into fine power after being condensed and processed by spray drying. The capsule is made by publicly known capsule technology and the weight of each capsule is 0.3g. The capsule has efficacy of nourishing the essential Qi, warning the stomach, inhibiting acid, stopping pain, activating blood, remedying ulcer and preventing recurrence. The capsule mainly cures peptic ulcer of deficiency cold of spleen and stomach type, and the symptoms of the disease are that the stomach is pain and is indulging in warm and press or pains at night with pantothenic acid and vomiting bitter.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a capsule for treating peptic ulcer and a preparation method thereof. Background technique [0002] Peptic ulcer is a common and frequently-occurring disease in clinical practice, and it is distributed globally. Hypersecretion of gastric acid, Helicobacter pylori infection and weakened protective effect of gastric mucosa are the main factors causing peptic ulcer. Factors and mental factors, etc., are closely related to the occurrence of peptic ulcer. Based on the research on the etiology of peptic ulcer, the current Western medicines for the treatment of peptic ulcer mainly include antacids, gastric acid secretion inhibitors, proton pump inhibitors, gastrin receptor antagonists, drugs for the eradication of Helicobacter pylori, and gastric mucoprotection. agent. However, the etiology of peptic ulcer is complicated, and none of the western medicines curr...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K9/48A61P1/04A61K35/56A61K35/618
Inventor 师彦平陈娟刘霞
Owner LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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