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Pharmaceutical combination for preventing birth defect and improving anamnesis

A technology for improving memory and birth defects. It is applied in drug combinations, active ingredients of heterocyclic compounds, and pharmaceutical formulations. It can solve the problems of few targets and lack of links, and achieve the effects of low cost, sufficient sources, and no side effects

Inactive Publication Date: 2008-10-29
BEIJING GUANWUZHOU BIOSCIENCE INSTITUTION (CN)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

No drug labels for preventing birth defects have been seen, only reports about folic acid being used for preventing neural tube defects; there are few targets and links, which need to be improved
However, the effect of preventing birth defects and improving memory and intelligence has not been seen in the same drug.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] formula:

[0027] Atractylodes macrocephala 5000mg (calculated as the whole natural medicinal material),

[0028] Cistanche cistanche 500mg (calculated based on the whole natural medicinal material),

[0029] Vitamin B 1 2mg,

[0030] Vitamin B 6 1.5mg,

[0031] Vitamin B 12 0.003mg,

[0032] Folic acid 0.6mg.

[0033] The above components are further uniformly mixed with appropriate amounts of additives such as magnesium aluminosilicate, polysolvate 60 and propylene glycol. The folic acid is first coated with microcapsules, and the resulting mixture is uniformly filled into capsules to obtain 9 capsules, each 3 times a day, 3 capsules each time.

Embodiment 2

[0035] formula:

[0036] Atractylodes macrocephala 600mg (calculated as the whole natural medicinal material),

[0037] Cistanche cistanche 500mg (calculated based on the whole natural medicinal material),

[0038] Vitamin B 6 2mg,

[0039] Vitamin B 12 0.008mg,

[0040] Folic acid 0.8mg.

[0041] The above components are further uniformly mixed with appropriate amounts of additives such as mannitol, hydroxypropyl cellulose, magnesium aluminosilicate and flavoring agents, wherein the folic acid is first coated with microcapsules, and then 3 packets of granules are made. Take 3 times a day, one sachet each time.

Embodiment 3

[0043] formula:

[0044] Atractylodes macrocephala 5000mg (calculated as the whole natural medicinal material),

[0045] Cistanche cistanche 500mg (calculated based on the whole natural medicinal material),

[0046] Vitamin B 1 1.8mg,

[0047] Vitamin B 6 0.8mg,

[0048] Vitamin B 12 0.01mg,

[0049] Folic acid 0.9mg,

[0050] Zinc citrate 20mg (calculated as elemental zinc),

[0051] Selenomethionine 0.05mg (calculated as elemental selenium).

[0052] Mix Atractylodes and Cistanche with appropriate amount of additives such as sodium citrate, malic acid, sucrose, benzoic acid and flavoring agent, and then make 3 packets of granules; firstly, folic acid is coated with microcapsules, and then with vitamin B 1 , B 6 , B 12 , Zinc, selenium and appropriate amount of starch, polyvinyl pyrrolidone, light anhydrous silicic acid, polyethylene glycol and flavoring agents are uniformly mixed to make 9 individual tablets; take 3 times a day, 1 packet each time, tablet 3 slices.

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PUM

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Abstract

The invention relates to a pharmaceutical composition for preventing birth defects and improving memory and intelligence, and the pharmaceutical composition comprises largehead atractylodes rhizome, desertliving cistanche, compound vitamin B and trace elements of zinc and selenium, the pharmaceutical composition is mainly applicable to pre-pregnancy women, pregnant women and lactating mothers and can effectively prevent the birth defects and improve the memory and the intelligence; furthermore, the pharmaceutical composition has the effects of health care and invigoration and does not have any side effects even in long-term application.

Description

Technical field: [0001] The invention relates to the technical field of medicines and health products. In particular, it is a pharmaceutical composition for preventing birth defects and improving memory and intelligence. Background technique: [0002] Birth defects refer to the developmental disorders of embryos and larvae caused by various factors in the process of fetal formation in the mother's body and organs after birth, including abnormal morphology, physiological and metabolic dysfunction, congenital mental retardation, and intrauterine growth retardation. 4 Kind of type. The incidence of birth defects in my country is as high as about 5% of the total number of births. Every year, children with congenital malformations and infants with defects that only appear several months after birth, and children with congenital disabilities are as high as about 1 million. It has a significant impact on the quality of the population and a heavy burden on families and society. It has be...

Claims

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Application Information

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IPC IPC(8): A61K36/64A61P3/02A61P25/00A61K31/194A61K31/198A61K31/4415A61K31/51A61K31/519A61K31/714
Inventor 朱炜
Owner BEIJING GUANWUZHOU BIOSCIENCE INSTITUTION (CN)
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