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Micro-current controlled cell chip

A cell chip and microfluidic technology, which can be used in tissue cell/virus culture devices, enzymology/microbiology devices, biochemical instruments, etc., and can solve problems such as inability to meet cell research.

Inactive Publication Date: 2008-09-24
SHENZHEN INST OF ADVANCED TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] Obviously, the current microfluidic cell chip cannot meet the requirements of this type of suspension culture cell research.

Method used

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Embodiment Construction

[0031] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0032] see figure 2 , is a schematic diagram of a microfluidic cell chip provided by an embodiment of the present invention. The microfluidic cell chip is a microfluidic cell chip in which adherent cultured cells and suspension cultured cells coexist.

[0033] The microfluidic cell chip has several cell culture units 210 . The several cell culture units 210 are arranged in an array.

[0034] Each cell culture unit 210 has a cell culture area 211 , a cell microchannel 212 and a drug microchannel 213 . Each cell microchannel has a cell microvalve 212a, and each drug microchannel 213 has a drug microvalve 213a.

[0035] The cell culture zone 220 has an inlet 220a and an outlet 220b.

[0036] One end of the cell microchannel 212 communicates with the inlet 220 a of the cell culture area 220 to transport the cell culture solution into the ce...

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Abstract

The invention provides a microflow control cell chip, which is provided with a plurality of cell culture units. Each cell culture unit is provided with a cell culture area, a cell microflow passage and a medicine microflow passage. The cell culture area is provided with an inlet and an outlet. The cell microflow passage is communicated with the inlet of the cell culture area to deliver cell culture medium to the cell culture area. The medicine microflow passage is communicated with the inlet of the cell culture area to feed medicine solution to the cell culture area. The cell culture area of the microflow control cell chip is provided with the inlet and the outlet, and the cell solution and the medicine solution are delivered through the inlet and the outlet so that the delivery direction of the cell culture medium is the same with the delivery direction of the medicine solution, thus preventing the medicine solution from carrying away the cells in the cell culture area.

Description

technical field [0001] The invention relates to the technical field of biochips, in particular to microfluidic cell chips in the field. Background technique [0002] The development of modern micro-manufacturing technology has driven a branch of the development of modern biology, which is the field of biochips. Biochip mainly refers to the integration of tens of thousands of densely arranged molecular arrays on a solid-state chip through microprocessing technology and microelectronics technology. The sample passes through the biochip, and the biological information in the sample can be quickly and accurately obtained. The efficiency is traditional. Detection means hundreds of times. [0003] The microfluidic cell chip is a kind of biochip. Cells are pre-cultured on a cell culture unit with a microfluidic channel, and a microvalve is made on the microfluidic channel, which can handle nanoliter (10 -9 L) or picoliters (10 -12 L) level of liquid flow control. The size of th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/02C12M3/04C12M1/36
Inventor 王站会
Owner SHENZHEN INST OF ADVANCED TECH
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