'Baidai Shenfang' oral preparation and preparation thereof

A technology of oral preparations and magic formulas, applied in the field of medicine, can solve the problems of inaccurate dosage, inability to commercialize, and large dosage of traditional Chinese medicine decoction.

Inactive Publication Date: 2008-09-17
BEIJING JINFANGHUA MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The ancient "leucorrhea formula" does not only have decoction, but it needs to be decocted and taken after purchasing decoction pieces. It is very inconvenient to carry and take it. After research, we have made modern oral preparations of traditional Chinese medicine through quantitative control of index components. The product dosage is accurate and the quality is stable. , easy to take, suitable for large-scale commercial production, overcomes the shortcomings of traditional Chinese medicine decoctions such as large dosage, inaccurate dosage, inconvenient carrying and taking, and inability to commercialize, and is convenient for clinical treatment and home use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Example 1: Preparation method of "White Belt Shen Fang" extract 1 (extract and volatile oil)

[0045] Prescription: Dongzhu 15g, Poria 10g, Red Celosia 10g, Plantago 15g.

[0046] Preparation method: cleanly select various medicinal materials for the prescription, weigh each medicinal material according to the prescription amount, add 6 to 15 times the amount of water to soak for 2-10 hours, heat and slightly boil for extraction 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was allowed to stand for 12-48 hours, filtered to take the supernatant, concentrated under reduced pressure to obtain an extract of about 16.2 g of water extract and about 1 mg of volatile oil.

Embodiment 2

[0047] Embodiment two: "Leucorrhizae shenfang" extract 2 (dry powder and volatile oil) preparation method

[0048] Prescription:: Dongzhu 15g, Poria cocos 9g, red cockscomb 9g, psyllium 4.5g.

[0049] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8 to 10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, the supernatant was collected by filtration, concentrated under reduced pressure, and spray-dried to obtain a dry powder of about 8.75 g of water extract and about 1 mg of volatile oil.

Embodiment 3

[0050] Embodiment three: preparation method of oral solid preparation of "White Belt God Prescription"

[0051] (1) Preparation of "White Belt God Prescription" Granules

[0052] prescription:

[0053] "Leucorrhea Shenfang" Extract 1 10-90%

[0054] Starch 5.0-70%

[0055] Dextrin 2.0-20%

[0056] Xylitol 5.0-20%

[0057] Methyl sorbate 0.001-2.0%

[0058] Preferred Prescription:

[0059] "White Belt Shen Fang" Extract 1 17.2g

[0060] Starch 3.0g

[0061] Dextrin 8.0g

[0062] Xylitol 2.0g

[0063] Methyl sorbate 0.002g

[0064] Preparation method: Prepare the extract of "White Belt God Prescription" powder according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dissolve the volatile oil with an appropriate amount of ethanol, spray evenly on the granules, dry at low temperature, pack and make become.

[0065] (2) Preparation of "White Belt God Prescription" tablet:

[0066] (1...

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PUM

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Abstract

The invention relates to a fabulous oral preparation for curing leucorrhea syndrome of women and the preparation method, which comprises largehead atractylodes rhizome and other three Chinese herbal medicines. The preparation is prepared using the mixed extract of largehead atractylodes rhizome, poria cocos, cockcomb flower and plantain seed as material, pharmaceutically acceptable carrier as matrix, and excipient according to conventional process. The preparation has the advantages of strengthening the spleen, clearing away heat, removing dampness through diuresis, curing leucorrhea syndrome of women, and effectively curing the colpitis and cervicitis according to long-term clinical application.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an oral preparation for mainly treating leucorrhea of ​​women and a preparation method thereof, in particular to an oral preparation using the extract of the traditional Chinese medicine prescription of leucorrhea shenfang as the active ingredient. Background technique [0002] "White Belt God Prescription" was created by Hua Tuo in the "Hua Tuo Review Secret Biography" in the late Han Dynasty. It has always been used as a common prescription for spleen deficiency and humid tropics. , heat-clearing, damp-damp effect, attending women leucorrhea syndrome. The long-term clinical application of the prescription shows that it has good curative effect on treating vaginitis, cervicitis, etc., and has wide application, and no obvious toxic and side effects have been found. [0003] The sources of Chinese herbal medicines in "White Belt God Prescription" are as follows: [...

Claims

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Application Information

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IPC IPC(8): A61K36/68A61K9/48A61K9/20A61K9/16A61K9/10A61K9/28A61K9/46A61K47/38A61K47/34A61K47/32A61P15/00A61P15/02A61K47/10A61K47/26A61K47/44
Inventor 张文芳
Owner BEIJING JINFANGHUA MEDICAL SCI TECH
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