Acorus calamus curcuma aromatica oral preparation and preparation thereof

A calamus turmeric and oral preparation technology, applied in the field of medicine, can solve the problems of large dosage of traditional Chinese medicine decoction, inaccurate dosage, inconvenient carrying and taking, etc.

Inactive Publication Date: 2008-08-13
张文芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The ancient "Calamus Yujin Decoction" only has decoctions, which need to be decocted and taken after purchasing decoction pieces. It is very inconvenient to carry and take. After research, we have made modern oral preparations of traditional Chinese medicine through quantitative control of index components. The product dosage is accurate and the quality is stable. It is convenient to take and is suitable for large-scale commercial production. It overcomes the shortcomings of traditional Chinese medicine decoctions such as large dosage, inaccurate dosage, inconvenient carrying and taking, and inability to commercialize. It is convenient for clinical treatment and home use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment one: "calamus turmeric" extract 1 (extract and volatile oil) preparation method

[0047] Prescription: Acorus calamus 9g, turmeric 6g, fried gardenia 9g, fresh bamboo leaves 9g, peony bark 9g, forsythia 6g, rush grass 6g, akebia 5.0g, bamboo leek 15g, Zijin slice 2.0g

[0048] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 6-15 times the amount of water to soak for 2-10 hours, heat and boil for 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to get the supernatant, concentrated under reduced pressure to obtain a medicinal extract of about 15.2 g of water extract and about 0.05 g of volatile oil.

Embodiment 2

[0049] Embodiment two: "calamus turmeric" extract 2 (dry powder and volatile oil) preparation method

[0050] Prescription: Calamus calamus 9g, turmeric 6g, fried gardenia 9g, fresh bamboo leaves 9g, peony bark 9g, forsythia 6g, rush grass 6g, akebia 4.5g, bamboo leek 15g, Zijin slice 1.5g

[0051] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8-10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts, collect volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to take the supernatant, concentrated under reduced pressure, and spray-dried to obtain a dry powder of about 14.6g of water extract; about 0.04g of volatile oil.

Embodiment 3

[0052] Embodiment three: "Calamus turmeric" oral solid preparation preparation method

[0053] (1) Preparation of "calamus turmeric" granules

[0054] prescription:

[0055] "Calamus turmeric" extract 1 10-90%

[0056] Starch 5.0-70%

[0057] Dextrin 2.0-20%

[0058] Xylitol 5.0-20%

[0059] Methyl sorbate 0.001-2.0%

[0060] Preferred Prescription:

[0061] "Calamus turmeric" extract 1 15.2g

[0062] Starch 3.0g

[0063] Dextrin 3.0g

[0064] Xylitol 2.0g

[0065] Methyl sorbate 0.002g

[0066] Preparation method: Prepare the extract of "Calamus turmeric" according to the method in Example 1, add the prescription amount of auxiliary materials to make granules according to the conventional method, dissolve the volatile oil with an appropriate amount of ethanol, spray evenly on the granules, dry at low temperature, and pack to make Two bags, each bag 12.6g.

[0067] (2) Preparation of "calamus turmeric" tablet:

[0068] (1) Ordinary tablet prescription:

[0069]...

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PUM

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Abstract

The present invention relates to an oral medicine preparation and a method for preparing the same, which is prepared from 10 Chinese traditional medicines mixed extract (extractum or dry powder and volatile oil) including glass leaved sweetflag rhizome, curcuma, fried gardenia, fresh bamboo leaf, paeony peel, forsythia, rush, mu tong, bamboo vinegar, zijinpian as raw materials, and acceptable carrier or excipient as substrate in medicine by conventional process. The medicine preparation has effects of clearing heat and promoting diuresis, eliminating phlegm for resuscitation, and is main used for treating damp-heat phlegm stagnation, beclouding pericardium, body heat and discomfortable, coma and delirium etc.

Description

technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to an oral preparation for mainly treating damp-heat phlegm turbidity, pericardium blindness, lack of body heat, coma and delirium and a preparation method thereof, in particular to an extract of a traditional Chinese medicine prescription of Calamus Yujin Decoction as the medicinal activity Composition of oral formulations. Background technique [0002] "Calamus turmeric soup" was created in "Went Disease Tiaodian" written by Wu Tang in the Qing Dynasty. It has always been used as a good prescription for clearing camp heat. Composed of forsythia, rushes, akebia, bamboo leek, and Zijin tablets, it has the functions of clearing heat and dampness, resolving phlegm and resuscitating, and it is mainly used to treat syndromes such as damp heat and turbid phlegm, blinded pericardium, lack of body heat, coma and delirium. The long-term clinical application of this prescription...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61K47/36A61K47/40A61K47/44A61P9/10A61P29/00
Inventor 张文芳曹世栋
Owner 张文芳
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