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Pulsation circulation type transdermal experiment instrument

An experimental instrument and cyclic technology, which is applied in the field of experimental instruments with transdermal properties, can solve the problems of poor transdermal effect and large gap in physiological characteristics, and achieve the effect of good transdermal effect.

Inactive Publication Date: 2008-07-16
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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AI Technical Summary

Problems solved by technology

[0004] The present invention aims to solve the shortcomings of the existing transdermal device and the human body in the physiological characteristics of the absorption of externally applied drugs, and the shortcomings of the poor transdermal effect, and provide a drug that is closer to the physiological characteristics of the human body and can more objectively reflect the transdermal preparation Transdermal Experimental Apparatus for Release Process

Method used

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  • Pulsation circulation type transdermal experiment instrument
  • Pulsation circulation type transdermal experiment instrument
  • Pulsation circulation type transdermal experiment instrument

Examples

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Embodiment Construction

[0016] Refer to the accompanying drawings: 1. Transdermal pool 2. Temperature sensor 3. Gland 4. Upper cover plate 5. Fastening screws and nuts 6. Upper sealing ring 7. Lower sealing ring 8. Experimental drug 9. Animal cortex 10. Bottom plate 11. Inlet channel 12. Outlet channel 13. Heat transfer aluminum plate 14. Asbestos plate 15. Heating box 16. Heating wire 17. XMT7110 micro temperature controller

[0017] The pulsating circulation type transdermal test apparatus of the present invention comprises a transdermal pool 1 filled with transdermal fluid, an animal skin 9 sealed on the transdermal pool, and a constant temperature heat source is installed under the transdermal pool 1 . Constant temperature heat source comprises heating box 15, and heating wire 16 is arranged in heating box 15, and asbestos board 14 is housed outside heating box 15, also has temperature display device, temperature control device, and temperature control device selects commercially available XMT7110...

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Abstract

A pulse circulation type transdermal testing apparatus including a transdermal pool with a transdermal liquid and an animal skin sealed on the transdermal pool. A homothermal heat source is arranged below the transdermal pool. A bottom plate of the transdermal pool is tightly stuck on the homothermal heat source. The transdermal pool is provided with a liquid inlet tube and a liquid discharging tube. The liquid inlet tube and the liquid discharging tube form a circulation loop of simulated blood in an organism tissue by a pulse liquid source.

Description

(1) Technical field [0001] The invention relates to a medicine experiment instrument, especially an experiment instrument for measuring the transdermal property of medicine in vitro. (2) Background technology [0002] The development of drugs for external use is very rapid in recent years, and the variety and quantity are increasing day by day, and have been welcomed by doctors and patients. Measuring the transdermal properties of drugs in vitro has certain significance for the design of drugs for external use and the prediction of release characteristics. Therefore, drug transdermal experiments have been concerned by many researchers in the medical field in recent years. Drug transdermal testing is necessary in many cases. Especially in the research of new drugs, external drugs, especially plaster drugs, can only be absorbed by the tissue through the dermis, so as to play a medicinal role. However, there are differences in the transdermal rate of different drug ingredien...

Claims

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Application Information

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IPC IPC(8): G01N33/15A61K49/00
Inventor 葛尔宁
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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