Medicament combination for regrouping leech essence
A technology for recombining hirudin and medicines, which is applied in the directions of medicine combinations, medicine formulations, and medical preparations containing active ingredients, and can solve the problems of aggravating HATII and the like
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[0009] The purpose of describing the embodiments of the present invention is to better explain how to implement the present invention. The purpose is only to illustrate, but not to limit the invention in any way.
[0010] 82 patients were divided into 4 groups for prospective multi-center phase III clinical trial. The diagnostic criteria of patients are based on clinical. (eg, in a platelet count drop greater than 30% or less than 10 9 / L, and thromboembolic complications concurrently or solely during heparin administration). Antibodies to HAT are also being studied in trials. Patients need to be 18 years old or older and have a definite need for injection antithrombotic therapy or prevention. The following patients were excluded: if the patient required hemodialysis or filtration due to severe renal failure, had poor compliance, was allergic to recombinant hirudin or was pregnant. Each patient provided informed consent to participate in the trial.
[0011] In the test g...
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