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Use of medicinal fatheadtree leaf in the preparation of antimicrobial anti-inflammation medicament

A kind of antibacterial and anti-inflammatory technology, bile tree leaves, applied in the anti-inflammatory and anti-inflammatory drugs, preparation of anti-bacterial and anti-inflammatory, bile wood leaves in the field of preparation of anti-bacterial and anti-inflammatory

Inactive Publication Date: 2008-03-12
邓世明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] "Danmuye" is a new medicinal part of the original plant of the traditional Chinese medicine "Danmu", its chemical composition and pharmacological effects have not been reported in any literature, especially "Danmuye" has antibacterial, anti-inflammatory, The pharmacological activity of swelling and pain relief has not been seen in any literature reports and patent publications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Grind 5000g of the medicinal material of gallbladder leaves into coarse powder, add 10, 8, and 8 times the amount of water, decoct and extract 3 times, filter the extract, combine the filtrates, pass through the macroporous adsorption resin column, wash the column with water, and then wash with 95% ethanol column, the ethanol eluent was concentrated under reduced pressure, dried in vacuum, crushed into fine powder, added appropriate amount of starch, mixed evenly, made into granules, dried, sized, packed into capsules, made into 1000 granules, and obtained.

Embodiment 2

[0013] Grind 2,500 g of the medicinal material of the gallbladder leaves into coarse powder, add 8, 6, and 6 times the amount of 60% ethanol, extract 3 times under hot reflux, filter the extract, combine the filtrates, concentrate under reduced pressure, dry in vacuum, grind into fine powder, add appropriate amount Mix polyvinylpyrrolidone, sodium carboxymethyl starch, and pregelatinized starch, sieve, granulate, dry, add appropriate amount of magnesium stearate, granulate, press into 1000 tablets, and coat with film.

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PUM

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Abstract

The present invention relates to a new medicinal part of Chinese medicine, namely, the purpose of biliary konoha in preparing antibacterial, anti-inflammatory and analgesic drugs. Studies show that biliary konoha includes alkaloid and flavonoid similar to konoha and these two ingredients have similar antibacterial, anti-inflammatory and analgesic pharmacological activity. The biliary konoha is extracted by water or ethanol of appropriate concentration; the extracted liquid is merged and filtered; the ethanol is washed through a macroporous resin column and the eluate is decompressed, concentrated and dried to obtain the biliary konoha extract including alkaloid and glycoside compounds. The extract mixed with an appropriate number of pharmaceutical auxiliary materials can be manufactured into oral solid dosage such tablet, capsule, granule and pill according to the conventional preparation process; or injection dosage such as water injection and powder injection according to the conventional injection preparation process.

Description

technical field [0001] The invention relates to the use of a new medicinal part of a Chinese medicinal material in the preparation of antibacterial, anti-inflammation, swelling and pain-relieving medicines, specifically the use of birch leaves in the preparation of anti-bacterial, anti-inflammation, swelling and pain-relieving medicines, which belongs to the field of traditional Chinese medicines. Background technique [0002] "Banmu" is a traditional Chinese medicinal material recorded in the 1977 edition of "Chinese Pharmacopoeia". It is the dry stem and root of the plant Nauclea officinalis in Rubiaceae. Efficacy, used for cold and fever, sore throat, boils of external auditory canal, acute conjunctivitis and skin boils. At present, there are two traditional Chinese medicine preparations in China, "Danmu Injection" and "Danmu Extract Tablet", which have been clinically used in upper respiratory tract infection, acute tonsillitis, acute pharyngitis, acute conjunctivitis an...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61P31/04A61P29/00A61K127/00
Inventor 邓世明杨先会
Owner 邓世明
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