Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Pharmaceutical composition having active ingredient of tamsulosin hydrochloride and finasteride

A technology of tamsulosin hydrochloride and finasteride, applied in the field of medicine, can solve problems such as undetermined exact relationship

Inactive Publication Date: 2008-01-23
BEIJING RUNDEKANG MEDICAL TECH CO LTD
View PDF0 Cites 12 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The occurrence of BPH is affected by many factors, such as smoking, obesity, drinking, race, genetics, hypertension, diabetes, sex life, socioeconomic status, etc. Although there are many studies on various factors, they are related to the occurrence of BPH Exact relationship still undetermined

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1 tamsulosin hydrochloride and finasteride tablet

[0017] prescription:

[0018] components

Dosage

Tamsulosin Hydrochloride

Finasteride

microcrystalline cellulose

CMS-Na

Magnesium stearate

90% ethanol

Co-made

0.2g

5g

88g

4g

3g

Appropriate amount

1000 pieces

[0019] Preparation:

[0020] Pass finasteride and microcrystalline cellulose through an 80-mesh sieve respectively, and mix them uniformly by the method of equal increments, and set aside; add tamsulosin hydrochloride to 90% ethanol, fully stir to dissolve, and set aside; Add the ethanol solution to the mixed powder, make soft material, granulate with a 24-mesh sieve, dry, granulate with a 20-mesh sieve, add magnesium stearate and CMS-Na, mix well, and press a suitable die to form a tablet.

Embodiment 2

[0021] Embodiment 2: Tamsulosin hydrochloride and finasteride capsules

[0022] prescription:

[0023] components

Dosage

Tamsulosin Hydrochloride

finasteride

microcrystalline cellulose

80% ethanol solution

Magnesium stearate

0.2g

5g

90g

Appropriate amount

3g

[0024] Preparation:

[0025] Pass finasteride and microcrystalline cellulose through an 80-mesh sieve respectively, and mix them uniformly by using the method of equal increments, and set aside; add tamsulosin hydrochloride to 80% ethanol, stir fully to dissolve, and set aside; Add the ethanol solution into the mixed powder, make soft material, granulate with a 24-mesh sieve, dry, granulate with a 24-mesh sieve, add magnesium stearate, pack separately, and obtain.

Embodiment 3

[0026] Example 3: Tamsulosin Hydrochloride and Finasteride Chewable Tablets

[0027] prescription:

[0028] components

Dosage

Tamsulosin Hydrochloride

Finasteride

Xylitol

Mannitol

Sweet Orange Flavor

aspartame

2% PVP-k30 ethanol solution

Magnesium stearate

0.4g

10g

500

250

15g

15g

Appropriate amount

10g

[0029] Preparation:

[0030] Pass the raw and auxiliary materials such as finasteride through an 80-mesh sieve respectively, and mix them uniformly by the method of equal increments, and set aside; add tamsulosin hydrochloride to 2% PVP-k30 ethanol solution, stir well to dissolve, and set aside; Add the binder solution into the mixed powder, make soft material, granulate with 16 mesh sieve, dry, granulate with 20 mesh sieve, add other correctives, sweeteners, glidants and mix evenly, tablet, that is have to.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a drug compound that takes tamsulosin hydrochloride and finasteride as its active ingredients as well as its preparation method and purpose. The invention, which takes tamsulosin hydrochloride and finasteride as its active ingredients and forms drug compound by mixing pharmaceutically acceptable supplementary materials, can be applied for the treatment of benign hyperplasia of prostate. The invention takes tamsulosin hydrochloride and finasteride as its active ingredients and adds the supplementary materials with certain portion and sorts, then develop them into tablet, capsule, dispersible tablet, chewable tablet, toroches and pill via the preparation technology in the invention.

Description

technical field [0001] The invention relates to a pharmaceutical composition with tamsulosin hydrochloride and finasteride as active components, a preparation method and application thereof, and belongs to the technical field of medicine. Background technique [0002] BPH is a common disease in elderly men, and the incidence rate increases with age, but there may not be clinical symptoms when there are hyperplastic lesions. The occurrence of BPH is affected by many factors, such as smoking, obesity, drinking, race, genetics, hypertension, diabetes, sex life, socioeconomic status, etc. Although there are many studies on various factors, they are related to the occurrence of BPH The exact relationship has yet to be determined. The incidence of BPH mainly comes from autopsy data, 40% of men aged 50, and 90% of men aged 80 have BPI-I histological changes. In the United States, about 1.7 million BPH patients go to outpatient clinics every year, about 300,000 people undergo pros...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/145A61K31/58A61P13/08
Inventor 陈瑞晶
Owner BEIJING RUNDEKANG MEDICAL TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com