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Woven artificial blood vessel in double layer structure

A technology of artificial blood vessels with a double-layer structure, applied in the direction of catheters, etc., can solve the problems that the smooth growth of cells and tissues cannot be realized at the same time, and blood seepage from the vessel wall.

Inactive Publication Date: 2011-04-27
DONGHUA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to provide a textile artificial blood vessel with a double-layer structure, so as to solve the defects in the prior art that the prevention of bleeding from the vessel wall during surgery and the smooth growth of cells and tissues cannot be realized at the same time.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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  • Woven artificial blood vessel in double layer structure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Use 300dtex / 250f polyester fiber filaments as warp yarns, 300dtex / 250f polyester fiber filaments as weft yarns, and the twist of warp yarns and weft yarns is 100 twists / m. The fabric weave is 3 / 1 twill, the warp density of the fabric is 400 threads / 10cm, and the weft density is 350 threads / 10cm. Woven tubular fabrics are manufactured on shuttle looms. The water permeability of the tubular fabric after getting off the machine is 1100ml / cm 2 · min · 16kPa.

[0020] The PEO resin (Mw=900,000) was dissolved in a solvent (water) to prepare a spinning solution with a resin ratio of 3 wt%.

[0021] Put the tubular fabric on the collection roller, apply an electrostatic voltage of 11kV between the spinning head and the collection roller, spin the spinning solution on the electrostatic spinning device to spin nanofibers, and rotate the collection roller at a constant speed to make the nanofibers evenly Lay on the surface of the tubular fabric. After the spinning is finished,...

Embodiment 2

[0024] Use 110dtex polyester fiber filaments with a twist of 120 twists / m to weave tubular fabrics on a double needle bed warp knitting machine. . The water seepage of the tubular fabric after getting off the machine is 2000ml / cm 2 · min · 16kPa.

[0025] The PVA resin is melted with a solvent (water) to prepare a spinning solution with a resin ratio of 3 wt%.

[0026] Put the tubular fabric on the collection roller, apply an electrostatic voltage of 11kV between the spinning head and the collection roller, spin the spinning solution on the electrostatic spinning device to spin nanofibers, and rotate the collection roller at a constant speed to lay the nanofibers evenly on the surface of the tube fabric. After spinning, the inside and outside of the tube are turned over, so that the nanofiber layer condensed on the outer layer is turned over to the inner layer of the tube fabric, and a tubular fabric with a double-layer structure tube wall is made.

[0027] The artificial ...

Embodiment 3

[0029] Use 110dtex polyester filaments with a twist of 120 twists / m to weave tubular fabrics on a double needle bed warp knitting machine. . The water seepage of the tubular fabric after getting off the machine is 3000ml / cm 2 · min · 16kPa.

[0030] The PVA resin is melted with a solvent (water) to prepare a spinning solution with a resin ratio of 3 wt%.

[0031] Put the tubular fabric on the collection roller, apply an electrostatic voltage of 11kV between the spinning head and the collection roller, spin the spinning solution on the electrostatic spinning device to spin nanofibers, and rotate the collection roller at a constant speed to lay the nanofibers evenly on the surface of the tube fabric. After spinning, the inside and outside of the tube are turned over, so that the nanofiber layer condensed on the outer layer is turned over to the inner layer of the tube fabric, and a tubular fabric with a double-layer structure tube wall is made.

[0032] The artificial blood ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Abstract

The present invention provides one kind of woven artificial blood vessel in double layer structure. The woven artificial blood vessel includes one woven outer layer and one inner layer of nanometer fiber. The woven artificial blood vessel can prevent blood permeation during surgical operation, is favorable to smooth growth of cell tissue to its inside after operation, and has high mechanical strength enough for being crinkled and being handled in operation.

Description

technical field [0001] The invention relates to an artificial blood vessel, in particular to a textile artificial blood vessel with a double-layer wall structure. Background technique [0002] In the 1950s, since the phenomenon of cells growing on silk soaked in blood was observed, the history of fabricating artificial blood vessels began. Since then, the selection of suitable fiber materials and ideal fabric structures has become the focus of artificial blood vessel research. Today, more than 50 years later, textile artificial blood vessels have been widely used in clinics to replace damaged blood vessels in the human body, and have achieved good clinical results. However, although textile artificial blood vessels have been widely used clinically, due to the function of promoting cell tissue growth and avoiding blood leakage during surgery, it is necessary to look for a textile artificial blood vessel with an ideal textile structure to obtain suitable wall pores. It is st...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L29/06
Inventor 丁辛李毓陵汪凌王璐杨旭东
Owner DONGHUA UNIV
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