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Method for preparing Chinese traditional medicine combination for curing gynecopathy

A technology for gynecological diseases and compositions is applied in the field of preparation of traditional Chinese medicine compositions, which can solve the problems of low drug loading, inconvenience for patients to carry and take, and long time consumption.

Inactive Publication Date: 2007-09-19
RENHE GRP DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The above methods have the following disadvantages: the extraction efficiency of the percolation method is low and time-consuming, and one process will affect the progress of the entire extraction process; the degree of refinement is low, the drug loading is low, and it has bad smell, which is inconvenient for patients to carry and take. have certain side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0115] prescription:

[0116] Licorice 5kg, Daqingye 15kg, Dandelion 15kg, Moutan Bark 15kg, Corydalis 15kg, Paeoniae Rubra 15kg, Rhubarb 10kg, Lonicera vine 50kg, Sargassum 50kg, Toosendan 15kg.

[0117] Preparation:

[0118] a. Take licorice, Folium Folium, Dandelion, Cortex Moutan, Corydalis Corydalis, Radix Paeoniae Rubra and Rheum officinalis, heat and reflux twice with 70% ethanol by volume, 2 hours each time, combine the extracts, filter, and recycle the ethanol from the filtrate to No alcohol smell, let stand for 24 hours, filter to obtain filtrate A; wherein the weight of the ethanol solution is 8 times the total weight of licorice, Folium Folium, Dandelion, Moutan bark, Corydalis Corydalis, Radix Paeoniae Rubra and Rhubarb;

[0119] b. Decoct Lonicera vine, Sargentine vine, and Toosendan with water twice, the first time is 2 hours, the second time is 1 hour, combine the decoctions, filter, and the relative density of the filtrate is 1.15 when concentrated to 60°C T...

Embodiment 2

[0123] prescription:

[0124] Licorice 3kg, Daqingye 20kg, Dandelion 10kg, Moutan Bark 14.9kg, Corydalis Corydalis 18kg, Radix Paeoniae Rubra 10kg, Rhubarb 8kg, Lonicera vine 49.9kg, Sargentina 55kg, Toosendan 18kg.

[0125] Preparation:

[0126] a. Take licorice, big green leaf, dandelion, Moutan cortex, Corydalis corydalis, Radix Paeoniae Rubra and rhubarb and heat reflux 3 times in 60% ethanol by volume, 2 hours for the first time, 1 hour for the second time, 1.5 for the third time hours, combined the extracts, filtered, and the filtrate reclaimed ethanol until there was no alcohol smell, left it for 48 hours, filtered, and obtained the filtrate A; wherein the weight of the ethanol solution was respectively licorice, Folium Isatidis, dandelion, Moutan bark, corydalis, 10, 8, and 6 times the total weight of Radix Paeoniae Rubra and Radix Rhubarb;

[0127] b. Decoct Lonicera vine, Sargentine vine, and Toosendan 2 times with water, the first time for 1 hour, and the second t...

Embodiment 3

[0131] prescription:

[0132] Licorice 7kg, Daqingye 10kg, Dandelion 18kg, Moutan Bark 10kg, Corydalis 15.1kg, Paeoniae Rubra 14.9kg, Rhubarb 15kg, Lonicera vine 50.1kg, Sargassum 55kg, Toosendan 14.9kg.

[0133] Preparation:

[0134] a. Take licorice, Folium Folium, Dandelion, Cortex Moutan, Corydalis corydalis, Radix Paeoniae Rubra and Rheum officinalis, heat and reflux twice in 80% ethanol by volume percentage, each time for 1.5 hours, combine the extracts, filter, and recycle the ethanol from the filtrate to No alcohol smell, let stand for 30 hours, filter to obtain filtrate A; the weight of the ethanol solution is respectively 6 and 9 times the total weight of licorice, Folium Isatidis, dandelion, Moutan bark, made Corydalis Corydalis, Radix Paeoniae Rubra and rhubarb;

[0135] b. Decoct Lonicerae vine, Sargentine vine, and Toosendan 3 times with water, for 1.5 hours for the first time, 1 hour for the second time, and 2 hours for the third time, combine the decoctions, f...

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Abstract

The invention discloses a method for preparing a traditional Chinese medicine composition in such a way that: alcohol extract of liquorice, dyers woad leaf, dandelion, cortex moutan radicis, prepared fumitory, red paeonia and prepared rhubarb is mixed uniformly with water extract of honey-suckle stem, sargentg loryvine and toosendan fruit, drying the same to form fine powder which is then added with pharmaceutic adjuvant in an acceptable quantity in medical science, accordingly, the preparation is produced. The preparation formed by the method of the invention has advantages of low toxic and side effect, simple extracting process, low production cost, large drug-loading rate, high purifying degree and manageable dosage, which is applicable to treat diseases of leukorrhea, celialgia and the like caused by pelvic inflammation, appendagitis, endometritis, etc.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition, in particular to a preparation method of a traditional Chinese medicine composition for treating gynecological diseases such as vaginal discharge and abdominal pain caused by pelvic inflammatory disease, adnexitis and endometritis. Background technique [0002] At present, there is a Chinese patent medicine "Fule Granule" in the market, which is used to treat leukorrhagia and abdominal pain caused by pelvic inflammatory disease, adnexitis, endometritis, etc., and the clinical application effect of the drug is good. The preparation method is as follows: take rhubarb and pulverize it into coarse powder, use 60% ethanol as a solvent according to the percolation method under the item of liquid extract and extract, use 60% ethanol as a solvent, carry out percolation after soaking for 24 hours, collect the percolation liquid, filter, reduce Concentrate under pressure...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K9/20A61K9/48A61P15/00
Inventor 杨文龙曾雄辉
Owner RENHE GRP DEV CO LTD
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