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Traditional Chinese medicine oral liquid for treating damnification of immunity function after chemotherapy of cancer of the esophagus cancer patient

A traditional Chinese medicine oral liquid, immune function technology, applied in antitumor drugs, drug combinations, pharmaceutical formulations, etc., can solve problems such as malnutrition, immune function damage, body damage, etc., achieve obvious curative effect, no toxic side effects, and reduce treatment costs Effect

Inactive Publication Date: 2010-01-27
杨文锋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] During the process of radiotherapy and chemotherapy, the drug lacks specific selection for tumor cells, and while killing cancer cells, it also damages normal cells to varying degrees. Almost all patients will experience varying degrees of toxic and side effects, such as: Loss of appetite, nausea, vomiting, fatigue, fatigue, decreased blood picture, anemia, etc., leading to body damage, physical weakness, malnutrition, immune function damage, and even some patients cannot adhere to treatment

Method used

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  • Traditional Chinese medicine oral liquid for treating damnification of immunity function after chemotherapy of cancer of the esophagus cancer patient
  • Traditional Chinese medicine oral liquid for treating damnification of immunity function after chemotherapy of cancer of the esophagus cancer patient
  • Traditional Chinese medicine oral liquid for treating damnification of immunity function after chemotherapy of cancer of the esophagus cancer patient

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Weigh 1000g of ginseng, 2000g of astragalus, 900g of Cordyceps, 1000g of Atractylodes macrocephala, 1500g of Poria cocos, 900g of licorice, 1200g of Chinese angelica, and 1500g of Chinese wolfberry. 450g half of licorice is roasted, and the other 450g is raw licorice. Mix the above drug materials, put them in a jacketed pot, add water over the surface of the drug for 2cm, soak for 10 minutes, heat and boil for 1.5 hours, cool and filter, add water to the filter residue and boil for 1 hour, filter, and combine the filtrate; the filter residue is soaked in 70% ethanol After 4 hours, squeeze and filter, combine the filtrates, then heat and distill to no alcohol, concentrate to 1ml liquid medicine containing 2g of native medicine, cool and filter, put in a 250ml bottle, seal, and steam at 100℃ After 30 minutes of inoculation, the traditional Chinese medicine oral liquid is obtained and ready to be taken.

[0042] Typical trial case: Li Haixia, one day before the start of chem...

Embodiment 2

[0045] Weigh 1100g of ginseng, 2100g of astragalus, 800g of Cordyceps, 900g of Atractylodes macrocephalae, 1600g of Poria cocos, 1000g of licorice, 1100g of angelica, and 1400g of Chinese wolfberry. 500g half of licorice is roasted. The preparation steps are the same as in Example 1. The method of administration is the same as in Example 1.

[0046] Typical trial case: Xie Fengxian, male, started 1 day before esophageal cancer surgical resection and chemotherapy, and took this formula of traditional Chinese medicine oral liquid according to this plan. 2 days before chemotherapy, peripheral blood IgG 12.13g / L, IgA2.45g / L, IgM 1.84 g / L; IL-2 is 1267g / L, IL-6 is 476g / L; Hb 131.2g / L, WBC 6.56×10 9 / L, PLT 213.4×10 9 / L. On the first day after chemotherapy, IgG 6.31g / L, IgA 1.37g / L, IgM 1.39g / L; IL-2 was 868g / L, IL-6 was 284g / L; Hb 102.3g / L, WBC 3.21×10 9 / L, PLT173.5×10 9 / L.

[0047] It improved significantly on the 7th day after chemotherapy, respectively, IgG 8.57g / L, IgA 1.74g / ...

Embodiment 3

[0049] Weigh 900g of ginseng, 1800g of astragalus, 1000g of Cordyceps, 1100g of Atractylodes macrocephala, 1400g of Poria cocos, 1000g of licorice, 1300g of Chinese angelica, and 1500g of Chinese wolfberry. 500g half of licorice is roasted. The preparation steps are the same as in Example 1.

[0050] Typical trial case: Han Ling, female, started to take the oral Chinese medicine of this formula one day before esophageal cancer resection and chemotherapy. Two days before chemotherapy, peripheral blood IgG 11.56g / L, IgA2.12g / L, IgM 1.67g / L; IL-2 was 1176g / L, IL-6 was 478g / L; Hb121.3g / L, WBC 6.54× 10 9 / L, PLT 243.4×10 9 / L. On the first day after chemotherapy, IgG 6.01g / L, IgA1.31g / L, IgM 1.35g / L; IL-2 was 812g / L, IL-6 was 259g / L; Hb 98.4g / L, WBC 3.06×10 9 / L, PLT 167.9×10 9 / L.

[0051] On the 7th day after the chemotherapy, it improved significantly, respectively, IgG 8.95g / L, IgA1.68g / L, IgM 1.59g / L, IL-2 was 987g / L, IL-6 was 384g / L, and Hb110.3g / L, WBC 3.72×10 9 / L, PLT 183...

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Abstract

The invention discloses a Chinese medicinal oral liquid for treating immunological function damage for patients of esophagus cancer after chemotherapy, wherein the oral liquid is prepared from the following raw materials (by weight proportion): ginseng 9-11%, astragalus root 18-22%, fine Chinese caterpillar fungus 8-10%, white atractylodes rhizome 9-11%, poria cocos wolf 14-16%, licorice root 8-10%, Chinese angelica root 11-13% and wolfberry fruit 14-16%.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine oral liquid for treating esophageal cancer patients with immune function damage after chemotherapy. Background technique [0002] Esophageal cancer is one of the most common malignant tumors in my country and the world. In recent years, the incidence rate has increased year by year. Its clinical manifestations are mainly progressive dysphagia, accompanied by pain behind the sternum or under the xiphoid process, etc., mostly The category of "choking" in Chinese medicine. The pathogenesis of esophageal cancer has not been fully elucidated so far. TCM believes that the main cause of tumors is stagnation of qi and blood stasis, phlegm dampness condensation, accumulation of evil toxins, insufficient righteousness, weakness of qi and blood, etc., which lead to dysfunction of viscera, and even stasis and phlegm It is caused by the accumulation of to...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61P37/02A61P35/00
Inventor 杨文锋王家林董传海宋晓娟
Owner 杨文锋
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