Application of Chinese medicine balloonflower as in-vitro spermaticide and method for preparing the medicament

Abstract

The invention discloses an application of the traditional Chinese medicine platycodon grandiflorum as an in vitro spermicidal medicine and a method for preparing the medicine. The Chinese medicine platycodon grandiflorum is used as a raw material for in vitro spermicidal medicine, and its extract is prepared into an emulsion or a suppository for vaginal contraceptive medicine. The preparation method of the medicine is to grind the bellflower raw material of traditional Chinese medicine, soak it in 0.9% normal saline, the ratio of the bellflower raw material to the normal saline is 100 grams: 900-1200 milliliters, place it in a metal bath at 100°C and heat it, take it out After filtering to remove slag, the extract of Platycodon grandiflora is obtained, and the extract of Platycodon grandiflorum is made into emulsion or suppository, which is used for killing sperm in vitro. Experiments of the present invention show that the extract of Platycodon grandiflorum has no stimulation and burning phenomenon on the vaginal mucosa, and has no destructive effect on the vaginal flora, is absorbed by the human body through the vaginal mucosa without any toxic and side effects on human organs, can be used for a long time, and has the advantages of convenient use Advantages, provide a non-toxic, cheap, easy to use, reliable contraceptive effect informed choice method for family planning.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, which is an application of the traditional Chinese medicine platycodon grandiflorum as an in vitro spermicide and a method for preparing the medicine. Background technique [0002] Among the contraceptive measures, intrauterine device, tubal ligation and vasectomy will all cause harm to the human body. For this reason, people use condoms or oral contraceptives to minimize the damage. However, long-term oral contraceptives will cause harm to the human body. Produce bigger side effect, and the use of condom still has certain probability of conception except that sensory property is poor, so this area is trying hard to study the medicine of in vitro spermicide again in recent years. The drugs used to kill sperm in vitro were the first to use imported drugs, and later more varieties were launched in China. Since the main ingredients of the drugs are all western medicines, it was found during use that...

AI Technical Summary

Problems solved by technology

In response to this situation, there are many reports on the spermicidal drugs of traditional Chinese medicine compositions, but due to the uncertainty of its toxic and side effects, and many reasons such as low spermicidal efficacy, it cannot be widely used so far.

Some compounds have been reported to kill sperm, but because these contraceptives have multiple functions such as bactericidal, virucidal, and spermicidal, and are suitable for areas where sexually transmitted diseases and AIDS are common, there are still toxic and side effects for contraceptives that are purely spermicidal