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Soft capsule containing extract of tree peony bar and cape jasmine and its preparation method

A technology for extracts and soft capsules is applied in the field of soft capsules containing Danzhi extract and its preparation, which can solve the problems of long-term retention, inconvenience in taking, old dosage forms, etc., and prevent volatile oils from being lost, carried and used. Convenient, full and long-lasting results

Active Publication Date: 2009-06-10
JILIN JINBAO PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the old dosage form and the original production process, there are problems such as large dosage, inconvenient taking, long disintegration time, slow absorption, and easy to be eaten by insects, which is not conducive to taking, storing and carrying.
[0003] In recent years, people in the industry have successively developed oral dosage forms such as tablets, hard capsules, and granules. Although some shortcomings of water pills have been overcome, the above-mentioned pills, tablets, and hard capsules cannot Oral dosage forms such as granules, granules, etc., often under natural conditions, the active ingredients of volatile oils will be lost with time, and cannot be retained for a long time, which affects the quality and curative effect of the drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Component Quantity (g / granule)

[0067] Extract 0.28

[0068] Salad oil 0.23

[0069] Beeswax 0.018

[0070] Palm oil 0.044

[0071] Soybean phospholipids 0.024

[0072] Gelatin 0.15

[0073] water 0.14

[0074] Glycerin 0.06

[0075] Methylparaben 0.004

Embodiment 2

[0077] Component Quantity (g / granule)

[0078] Extract 0.12

[0079] soybean oil 0.15

[0080] Wax 0.04

[0081] Palm oil 0.07

[0082] Hydrogenated palm oil 0.05

[0083] Gelatin 0.12

[0084] water 0.12

[0085] Glycerin 0.046

[0086] Methylparaben 0.0029

[0087] Ethyl p-hydroxybenzoate 0.0001

Embodiment 3

[0089] Component Quantity (g / granule)

[0090] Extract 0.46

[0091] Propylene glycol 0.038

[0092] Polyethylene glycol 0.16

[0093] a-tocopherol 0.001

[0094] Methylcellulose 0.002

[0095] Gelatin 0.16

[0096] water 0.15

[0097] Glycerin 0.06

[0098] Methylparaben 0.004

[0099] The preparation process of the soft capsule preparation containing Danzhi extract in the above-mentioned 1-3 embodiments is specifically as follows: (1) take gelatin, pure water, stir until dissolved, add glycerin and an appropriate amount of preservative, stir evenly, after vacuuming and degassing, Keep warm.

[0100] (2) Weigh the extract and volatile oil according to the prescription amount, mix with pharmaceutical excipients, stir evenly to make a suspension, and let stand at room temperature.

[0101] (3) Pour the prepared medicinal liquid into the medicinal liquid hopper, and press it into a soft capsule with a mold. After setting the shape, drying, selecting pills, washing the c...

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PUM

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Abstract

The invention relates to a soft capsule containing Danzhi extract and method of preparation, wherein the soft capsule comprises medicinal soup and capsule shells, the medicinal soup includes Danzhi extract and medicinal adjuvant, while the wherein the capsule shell comprises gelatine, water, glycerine and preservative agent. Each tablet of the capsule contains Danzhi extract 50-1000mg.

Description

technical field [0001] The invention relates to a traditional Chinese medicine oral preparation, in particular to a soft capsule containing an extract of danzhi and a preparation method thereof. Background technique [0002] The soft capsule prescription containing Danzhi extract of the present invention comes from Jiawei Xiaoyao Pills, also known as Danzhi Xiaoyao Pills. It is a classic prescription of traditional Chinese medicine, which is recorded in the first part of the Chinese Pharmacopoeia 2000 edition. It is made of crushing and mixing 9 Chinese medicinal materials such as Bupleurum, Moutan, Gardenia, and white peony, and taking ginger decoction and pan pills. It has the functions of soothing the liver and clearing away heat, invigorating the spleen and nourishing blood. Indications of liver depression and blood deficiency, disharmony between liver and spleen. Pain in both hypochondriacs, dizziness, fatigue, lack of food, irregular menstruation. Umbilical abdomina...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K36/9068A61K36/744A61K36/71A61K36/534A61K36/484A61P1/14A61P43/00
Inventor 于丽云白雪
Owner JILIN JINBAO PHARM CO LTD
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