134results about How to "Rapid reversible binding reaction" patented technology

The invention relates to a dual-driving coupling operated multichannel micro-fluidic chip device used for cholera diagnosis and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for cholera diagnosis. But there exist a series of problems. The scheme aims to solve the series of problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure are intercoupling with each other and operate collaboratively. Then, the problems are solved.

The invention relates to a cholera diagnosis microfluidic device with a chip using a strong hydrophobic substrate and belongs to the field of analysis and testing. At present, there are practical problems in preparation of a microfluidic chip substrate for diagnosing cholera from cheap and easily processed polydimethylsiloxane PDMS. The PDMS has the strongly hydrophobic surface and the specifically improved or modified surface has no lasting effect. The hydrophobic substrate-containing multi-channel microfluidic chip device solves the above problem. PDMS with the original ecological surface is selected as a substrate, a hinge fixture with a micro-ultrasonic transducer is manually fastened to a position close to a test sample liquid flow terminal of the microfluidic chip, a sample feeding end of the microfluidic chip is provided with an ultrasonic attenuator for fast degression of ultrasonic intensity in a short distance so that two ends of the chip form interfacial tension difference and the sample liquid flows to the terminal along a hydrophobic capillary channel direction.

The invention relates to a multichannel and dual-driving coupling operated micro-fluidic chip device used for cholera diagnosis and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for diagnosis of cholera. But there exist a series of problems. The scheme aims to solve the series of problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure operate collaboratively. Thus, the series of problems are solved.

The invention relates to a subtype swine influenza detection device with an easy-to-remove liquid driving component, and belongs to the field of analytical testing. The subtype swine influenza detection device aims to solve related problems that various obstacles exist when cheap and easy-to-process polydimethylsiloxane (PDMS) is utilized to prepare a substrate of a micro-fluidic chip for subtype swine influenza diagnosis, and the effect of targeted surface modification or surface finish is difficult to last due to strong hydrophobicity of the surface of a PDMS material. The subtype swine influenza detection device is characterized in that the substrate adopts the PDMS with an original surface, an elastic clamp with clamping arms equipped with attached miniature ultrasonic transducers is elastically snapped and located in the position adjacent to a sample liquid flow terminal of the micro-fluidic chip, an ultrasonic attenuator is installed in the sample feeding end of the micro-fluidic chip to achieve rapid ultrasonic intensity decrease in a short distance, so that interfacial tension difference is formed at two ends of the chip, and the sample liquid flow is enabled to flow in a direction of the terminal along a capillary channel.

The invention relates to a cheap micro-fluidic device for diagnosis of cholera and with a specific liquid flow transmission manner, belonging to the field of analysis and testing. A series of obstacles exist in preparation of a substrate for a cholera diagnosis micro-fluidic chip from cheap and easily workable polydimethylsiloxane (PDMS); a PDMS material has a strongly hydrophobic surface and the effect of targeted surface modification cannot last for a long time; and the invention aims to overcome a series of such problem. According to main points of a technical scheme in the invention, PDMS with an original surface is selected as a substrate; a minisized ultrasonic transducer is arranged at a position close to a sample liquid flow terminal of a micro-fluidic chip in an adhesion manner, and an ultrasonic wave reducing device is arranged on the sample introduction terminal of the micro-fluidic chip, so the intensity of ultrasonic waves rapidly and progressively decreases in a short distance; thus, difference of interfacial tension at the two terminals of the chip is formed, which leads to formation of pressure difference between the two terminals, and the pressure difference drives sample liquid flow to flow towards the sample liquid flow terminal along a capillary channel.

The invention relates to a cholera diagnosis microfluidic device with a fast-to-remove liquid flow driving accessory, and belongs to the field of analytical testing. The cholera diagnosis microfluidic device with the fast-to-remove liquid flow driving accessory aims to solve related problems that a series of difficulties actually exist when cheap and easy-to-process polydimethylsiloxane (PDMS) is utilized to prepare a substrate of a micro-fluidic chip for cholera diagnosis, and the effect of targeted surface modification or surface finish is difficult to last due to strong hydrophobicity of the surface of a PDMS material. Main points of the cholera diagnosis microfluidic device with the fast-to-remove liquid flow driving accessory are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along a capillary channel to the direction of the terminal.

The invention relates to an AIDS diagnosis device with an easy-to-remove liquid flow driving component, and belongs to the field of analytical testing. A technical obstacle exists in the manufacture of a substrate of an AIDS-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane (PDMS), the surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the AIDS diagnosis device with the easy-to-remove liquid flow driving component aims to solve the series of relevant problems. Main points of the AIDS diagnosis device with the easy-to-remove liquid flow driving component are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

The invention relates to a dual-driving coupled micro-fluidic chip device for simultaneous detection of various subtype swine influenzas and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for diagnosis of subtype swine influenzas. In fact, there exist a series of problems. The scheme aims to solve the problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure support each other, are intercoupling with each other, adjust and adapt mutually, and operate collaboratively.

The invention relates to a dual-driving coupling operated micro-fluidic chip device used for syphilis diagnosis and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for syphilis diagnosis. But there exist some problems. The scheme aims to solve the problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure support each other, are intercoupling with each other, adjust and adapt mutually, and operate collaboratively.

The invention relates to a multi-channel micro-fluidic chip device for simultaneously detecting various kinds of subtype swine flu and belongs to the field of analytical testing. When polydimethylsiloxane, namely PDMS, which is cheap and extremely easy to process is used for making a substrate of a micro-fluidic chip for diagnosing subtype swine flu, many obstacles exist; the surface of a PDMS material is strongly hydrophobic, while the effect of specific surface modification cannot last. According to the scheme, the multi-channel micro-fluidic chip device aims at solving the series of related problems, and is characterized in that PDMS with an original surface is selected as a substrate, a miniature ultrasonic transducer is attached to and arranged at the position close to the sample liquid flow terminal of a micro-fluidic chip, and interfacial tension is reduced with ultrasonic waves; meanwhile, the strong absorption capability of PDMS to ultrasonic waves is utilized for quickly reducing the intensity of the ultrasonic waves gradually in a short distance, an interfacial tension difference is formed at the two ends of the chip accordingly, a pressure difference is formed between the two ends, and the sample liquid flow is driven to flow towards the terminal along capillary channels by the pressure difference.

The invention relates to a syphilis diagnosis microfluidic device with an easy-to-remove additional liquid flow driving component, and belongs to the field of analytical testing. A technical target is manufacture of a substrate of a syphilis-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane (PDMS), the surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the syphilis diagnosis microfluidic device with the easy-to-remove additional liquid flow driving component aims to solve the series of relevant problems. Main points of the syphilis diagnosis microfluidic device with the easy-to-remove additional liquid flow driving component are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

The invention relates to a syphilis diagnosis device with an easy-to-remove additional sample driving component, and belongs to the field of analytical testing. A series of problems exist in manufacture of a substrate of a syphilis-diagnosis microfluidic chip using cheap and easy-to-process polydimethylsiloxane (PDMS), the surface of the PDMS is strongly-hydrophobic, the effect of targeted surface modification or surface finish is difficult to last, and the syphilis diagnosis device with the easy-to-remove additional sample driving component aims to solve the series of relevant problems. Main points of the syphilis diagnosis device with the easy-to-remove additional sample driving component are as follows: the PDMS with an original ecological surface is selected as the substrate, an elastic force clip is elastically snapped and positioned in a position near a sample liquid flow terminal of the microfluidic chip, wherein miniature ultrasonic transducers are attached to clamping arms of the elastic force clip, meanwhile an ultrasonic attenuator is installed at the sample feeding end of the microfluidic chip so as to achieve a rapid ultrasonic wave intensity decline in a short distance, so that an interfacial tension difference can be formed at both ends of the chip, and a sample flow is facilitated to flow along an originally-hydrophobic capillary channel to the direction of the terminal.

The invention relates to a simple disassembled and assembled chip device for combined detection of typical tumor markers, which belongs to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for multi-channel joint detection of typical tumor markers. It has advantages and a series of problems that need to be solved; this case is aimed at this series of problems. The gist of this case is that the substrate is selected from PDMS with an original ecological surface, and the hinged fixture with a micro-ultrasonic transducer is manually fastened and positioned in the vicinity of the sample liquid flow terminal of the microfluidic chip, so as to Ultrasound reduces the interfacial tension, which greatly increases the interfacial compatibility between the relevant solid-liquid two phases. At the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves within a short distance, thereby forming an interface at both ends of the chip. The difference in tension thereby facilitates the flow of the sample fluid toward the terminal along the originally hydrophobic capillary channel. The device does not require a micropump.

The invention relates to an easily-dismountable multichannel device for cholera diagnosis and belongs to the field of analysis and testing. By using cheap and easily-processable polydimethylsiloxane,namely PDMS for manufacturing a substrate of a microfluidic chip for cholera diagnosis, a series of problems exist. The surface of the PDMS material is strongly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, a chain-ring electromagnetic fixture attached with a miniature ultrasonic transducer is in cup joint to be positioned near the terminal of a sample liquid fluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacial tension differencebetween two ends of the chip. Thereby, the sample liquid fluid is driven to flow along an originally hydrophobic capillary channel towards the terminal.

The invention relates to an AIDS diagnosing device having an easily removably functional member used for driving an additionally added sample liquid, and belongs to the field of analysis testing. A technical objective is to prepare substrates of micro-fluidic chips used for AIDS diagnosis by utilizing polydimethylsiloxane, namely PDMS that is cheap and easy to process, but the PDMS material has a strongly hydrophobic surface, and targeted surface modification or surface decoration fails to achieve durable effects. The objective of the device is to overcome the series of problems. The device is characterized in that PDMS having an original surface is adopted as a substrate, a chain-ring type electromagnetic clamp equipped with a minitype ultrasonic transducer is positioned at a position near a sample liquid stream terminal of a micro-fluidic chip in a sleeve joint manner, and an ultrasonic attenuator is mounted at a feeding end of the micro-fluidic chip to achieve rapid ultrasonic wave intensity attenuation in a short distance, and therefore an interfacial tension difference is formed between the two ends of the chip, thus allowing the sample liquid stream to flow along originally hydrophobic capillary channels towards the terminal direction.

The invention relates to an acquired immunodeficiency syndrome diagnosis apparatus adopting a hydrophobic material as the substrate of a microfluidic chip, and belongs to the field of analysis testing. According to the present invention, the use of inexpensive and easily-processed polydimethylsiloxane (PDMS) to produce the substrate of a microfluidic chip for diagnosing acquired immunodeficiency syndrome is a technical target, but the surface of the PDMS material is strongly hydrophobic and the effect of the targeted surface modification or surface modifying is difficult to lasting, and a purpose of the present invention is to solve the series of the related problems; and the apparatus is characterized in that the substrate selects the PDMS having an original ecological surface, a hinge type fixture provided with a miniature ultrasonic wave transducer is manually fastened and positioned at a position close to the sample liquid fluid terminal end of the microfluidic chip so as to reduce the interfacial tension through the ultrasonic wave, and the strong absorption capacity of the PDMS on the ultrasonic wave is used to rapidly decrease the intensity of the ultrasonic wave within a short distance, such that the interfacial tension difference is formed on both ends of the chip so as to promote the sample liquid fluid to flow to the terminal direction along the originally-hydrophobic capillary channel.

The invention relates to a six-channel micro-fluidic chip device for combined detection of abridged tumor markers, belonging to the field of analytical testing. The micro-fluidic chip device used for producing a substrate of the micro-fluidic chip for combined detection of classic tumor markers prepared from PDMS (polydimethylsiloxane) has advantages and a series of difficulties; and the invention aims at solving the series of difficulties. The invention is mainly characterized in that PDMS with originally ecological surface is selected as the substrate, a chain ring type electromagnetic clamp with a minitype ultrasonic energy transducer is sheathed at and positioned at a position close to the liquid flow end of a test sample of the micro-fluidic chip, the interfacial tension is reduced ultrasonically, so that the interfacial compatibility between the solid and liquid phases is greatly increased, the ultrasonic intensity is rapidly decreased progressively within short distance by utilizing the strong absorption capability of PDMS to ultrasonic wave, so that the interfacial tension difference is formed at the two ends of the chip, therefore, the liquid flow of the test sample is driven to flow to the end along the direction of originally hydrophobic capillary channel. The device does not use a micropump.

The invention relates to a micro-fluidic chip device for combined detection of multiple female classic tumor markers, belonging to the field of analytical testing. The micro-fluidic chip device used for producing a substrate of the micro-fluidic chip for combined detection of eight female classic tumor markers through PDMS (polydimethylsiloxane) has both price and technology advantages and difficulties. The invention aims at solving the difficulties. The invention has the characteristics that PDMS with originally ecological surface is selected as the substrate, a chain ring type electromagnetic clamp with a minitype ultrasonic energy transducer is sheathed at and positioned at a position close to the liquid flow end of a test sample of the micro-fluidic chip, the interfacial tension is reduced ultrasonically, so that the interfacial compatibility between the solid and liquid phases is greatly increased, the ultrasonic intensity is rapidly decreased progressively within short distance by utilizing the strong absorption capability of PDMS to ultrasonic wave, so that the interfacial tension difference is formed at the two ends of the chip, therefore, the liquid flow of the test sample is driven to flow to the end along the direction of originally hydrophobic capillary channel. The device does not use a micropump.

The invention relates to an easily disassembled chip device for joint detection of typical male tumor markers, which belongs to the field of analysis and testing. Polydimethylsiloxane, or PDMS, is used to make the substrate of a microfluidic chip for the joint detection of seven typical tumor markers in men. It has many advantages, but there are also a series of problems; this case is aimed at this series of problems. The gist of this case is that the substrate is selected from PDMS with an original ecological surface, and the hinged fixture with a micro-ultrasonic transducer is manually fastened and positioned at the position adjacent to the sample liquid flow terminal of the microfluidic chip, so as to Ultrasound reduces the interfacial tension and greatly increases the interfacial compatibility between solid and liquid phases. At the same time, the strong absorption ability of PDMS to ultrasonic waves is used to achieve a rapid decrease in the intensity of ultrasonic waves within a short distance, thereby forming a difference in interfacial tension at both ends of the chip. , thereby promoting the flow of the sample liquid to flow toward the terminal along the originally hydrophobic capillary channel. The device does not require the use of micropumps.

The invention relates to a micro-fluidic chip device with a dual driving coupling mode and used for diagnosis of AIDS and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for diagnosis of AIDS. But there exist a series of problems. The scheme aims to solve the series of problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure support each other and operate collaboratively. Thus, the problems are solved.

The invention relates to a cheap micro-fluidic device used for diagnosis of syphilis and realizing liquid flow transmission via interfacial characteristics, belonging to the field of analysis and testing. A few problems exists in preparation of a substrate used for syphilis diagnosis micro-fluidic chips from cheap and easily workable polydimethylsiloxane, i.e., PDMS; a PDMS material has a strongly hydrophobic surface and the effect of targeted surface modification cannot last for a long time; and the invention aims to overcome a series of such problems. According to main points of a technical scheme in the invention, PDMS with an original surface is selected as a substrate; a minisized ultrasonic transducer is arranged at a position close to a sample liquid flow terminal of a micro-fluidic chip in an adhesion manner, and an ultrasonic wave reducing device is arranged on the sample introduction terminal of the micro-fluidic chip, so the intensity of ultrasonic waves rapidly and progressively decreases in a short distance; thus, difference of interfacial tension at the two terminals of the chip is formed, which leads to formation of pressure difference between the two terminals, and the pressure difference drives sample liquid flow to flow towards the sample liquid flow terminal along a capillary channel.

The invention relates to an acquired immune deficiency syndrome diagnosis micro-fluidic chip device adopting a dual drive coupling mode, and belongs to the field of analytical testing. When cheap polydimethylsiloxane, namely, PDMS easy to process is used for manufacturing a substrate of a micro-fluidic chip for acquired immune deficiency syndrome diagnosis, a series of problems exist. The scheme aims at the series of problems. According to the scheme, the PDMS with an original ecological surface is selected in the substrate, a micro ultrasonic transducer is fixedly installed at the position close to a sample liquid flow terminal of the micro-fluidic chip, interfacial tension is reduced through ultrasonic waves, meanwhile, the high absorption capacity of PDMS to the ultrasonic waves is utilized, the ultrasonic intensity is fast reduced within a short distance, and therefore an interfacial tension difference is formed between the two ends of the chip. Power for driving sample liquid flow to flow along a hydrophobic capillary channel in the terminal direction is provided through the difference, the power and the mechanical pumping power of a micropump included in the structure support each other and collaboratively operate, and the series of problems are all solved through the scheme.

The invention relates to an AIDS diagnosis device with an easily-detachable component used for driving a to-be-tested sample liquid, belonging to the fields of analysis and testing. The invention aimsto solve a series of related problems that manufacturing of a substrate of a microfluidic chip used for AIDS diagnosis from cheap and easily-processed polydimethylsiloxane (PDMS) has a technical obstacle; and the PDMS material has highly-hydrophobic surface and is difficult to obtain lasting effects through targeted surface modification or surface decoration. The invention has the following mainpoints: PDMS with original ecological surface is selected as the substrate; a link type electromagnetic fixture equipped with a miniature ultrasonic transducer is in sleeve connection with and is positioned at a position close to the terminal of a sample liquid flow of the microfluidic chip; ultrasonic wave is used to reduce the interfacial tension; meanwhile, strong absorption capacity of the PDMS to the ultrasonic wave is utilized, so rapid decrease of ultrasonic intensity in a short distance is realized, and an interfacial tension difference between two terminals of the chip is formed; thus, the sample liquid flow is driven to flow to the terminal direction along original hydrophobic capillary channels.

The invention relates to a cheap microfluidic device with specific liquid flow transmission mode and for cholera diagnosis and belongs to the field of analysis and testing. By using cheap and easily-processable polydimethylsiloxane, namely PDMS for manufacturing a substrate of a microfluidic chip for cholera diagnosis, a series of problems exist. The surface of the PDMS material is strongly hydrophobic. Through targeted surface modification, the effect is hard to last. The scheme aims to solve the series of related problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, a miniature ultrasonic transducer is arranged near the terminal of a sample liquid fluid of the microfluidic chip, interfacial tension is reduced by ultrasonic wave, and by PDMS's strong absorption of ultrasonic wave, ultrasonic intensity is rapidly decreased progressively in a short distance to form interfacial tension difference between two ends of the chip. The interfacial tension difference leads to formation of pressure difference between the two ends, and the pressure difference drives the sample liquid fluid to flow along the capillary channel towards the terminal.

The invention relates to a micro-fluidic chip device used for diagnosis of AIDS and based on a dual-driving coupling operation mode and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for diagnosis of AIDS. But there exist a series of problems. The scheme aims to solve the series of problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force and a mechanical pumping force of a micropump contained in the structure are intercoupling with each other. Thus, the problems are solved.

The invention relates to a syphilis diagnosis micro-fluidic apparatus with a liquid flow driving additional member being easy to detach and belongs to the field of analysis and test. In the prior art, a process of producing a substrate of a syphilis diagnosis micro-fluidic chip with polydimethylsiloxane (PDMS), which is low in cost and is easy to process, becomes a technical target. The PDMS has an intensive hydrophobic surface, and effects of specific surface modification and the like cannot be maintained durably, so that the invention aims to solve the related problems. In the embodiment, PDMS having an original ecological surface is employed as the substrate, wherein an elastic clamp, of which a clamping arm is equipped with a micro-ultrasonic transducer, clamps and is located on a position nearby a terminal of a test sample fluid in the micro-fluidic chip through elasticity, so that ultrasonic wave reduces interface tension; and meanwhile, with the strong absorption capability of the PDMS to the ultrasonic wave, quick attenuation of intensity of the ultrasonic wave in a short distance is achieved, thus forming difference between the interface tensions at the two ends of the chip, so that the test sample fluid flows to the direction of the terminal along a capillary path which is originally hydrophobic.

The invention relates to a multichannel cholera diagnosis micro-fluidic chip device operating in a double-drive coupling mode, and belongs to the field of analytical tests. A series of problems exist if polydimethylsiloxane, namely, PDMS which is cheap and very easy to process is used for manufacturing a substrate of a cholera diagnosis micro-fluidic chip, and the micro-fluidic chip device aims at solving the series of problems. The micro-fluidic chip device is characterized in that PDMS with an original surface is selected as a substrate, a micro ultrasonic transducer is fixedly installed at the position close to a sample liquid flow terminal of the micro-fluidic chip to reduce the interfacial tension with ultrasonic waves, meanwhile, the strong absorption capability of PDMS on ultrasonic waves is utilized to rapidly reduce the ultrasonic wave intensity within a short distance, and thus an interface tension difference is formed between the two ends of the chip; the difference provides a force driving sample liquid flow to flow towards the terminal along a hydrophobic capillary channel, and meanwhile the force cooperates with the mechanical pumping force of a micropump included in the structure. Thus, the series of problems are overall solved.

The invention relates to a micro-fluidic chip device used for syphilis diagnosis and based on dual driving coupling operation principle and belongs to the field of analytical testing. Cheap and easily-processed polydimethylsiloxane, namely PDMS is used for manufacturing a substrate of a micro-fluidic chip for syphilis diagnosis. In fact, there exist a series of problems. The scheme aims to solve the series of problems. According to main points of the scheme, PDMS with primitive surface is selected as the substrate, and a miniature ultrasonic transducer is fixedly installed at the position near a sample fluid terminal of the micro-fluidic chip. Meanwhile, an ultrasonic attenuator is arranged at a sampling end of the micro-fluidic chip so as to rapidly decrease ultrasonic intensity progressively in a short distance. Therefore, interfacial tension difference is formed between two ends of the chip. The different provides a force for driving the sample fluid to flow along a hydrophobic capillary channel towards the terminal. The force is coupled with mechanical pumping force of a micropump contained in the structure. Thus, the series of problems are solved.

The invention relates to a multichannel micro-fluidic chip device capable of simultaneously detecting multiple swine influenza virus subtypes, belonging to the field of analysis and testing. A series of obstacles practically exist in preparation of a substrate for a swine influenza virus subtype diagnosis micro-fluidic chip from cheap and easily workable polydimethylsiloxane (PDMS); and a PDMS material has a strongly hydrophobic surface; and the effect of targeted surface modification cannot last for a long time. The objective of the invention is to overcome the above problems. According to main points of a technical scheme in the invention, PDMS with an original surface is selected as a substrate; a minisized ultrasonic transducer is arranged at a position close to a sample liquid flow terminal of a micro-fluidic chip in an adhesion manner, and an ultrasonic wave reducing device is arranged on the sample introduction terminal of the micro-fluidic chip, so the intensity of ultrasonic waves rapidly and progressively decreases in a short distance; thus, difference of interfacial tension at the two terminals of the chip is formed, which leads to formation of pressure difference between the two terminals, and the pressure difference drives sample liquid flow to flow towards the sample liquid flow terminal along a capillary channel.

The invention relates to a syphilis diagnosis apparatus used for sample driving and capable of rapidly removing an attached member, belonging to the field of analysis and testing. A substrate used for preparation of syphilis diagnosis micro-fluidic chips and prepared from cheap and easily workable polydimethylsiloxane, i.e., PDMS, have the problems that the PDMS material has a strongly hydrophobic surface; and the effect of directed surface modification cannot last for a long time. The objective of the invention is to overcome the problems. According to main points of a technical scheme in the invention, PDMS with an original surface is selected as a substrate; an elastic clamp, additionally provided with a minisized ultrasonic transducer, of a clamping arm of the substrate is positioned at a position close to a sample liquid flow terminal of a micro-fluidic chip in the manner of elastic occlusion, and ultrasonic waves are used for reducing interfacial tension; meanwhile, in virtue of strong ultrasonic wave absorption capacity of PDMS, rapid and progressive decrease of ultrasonic intensity is realized in a short distance; thus, difference of interfacial tension at two ends of the chip is formed, and sample liquid flow is allowed to flow towards the terminal along an originally-hydrophobic capillary channel.