30 results about "Hyperplasia Suppressor Gene" patented technology

The invention relates to the molecular biology and medicine field, in particular to a method for detecting essential hypertension susceptibility, which comprises the following steps of detecting the genotype at a site of rs3753579 of an individual mitochondrion fusion gene 2 (Mfn2) / hyperplasia suppressor gene (HSG), and thus judging whether the risk of the individual to suffer from essential hypertension is larger than that of common people. The invention also discloses a corresponding detection kit. By detecting the genotype at the site of rs3753579, the method is simple, practicable, fast, high efficient and low-cost, and provides a new short-cut way to the diagnosis and the treatment of hypertension.

The invention belongs to the fields of molecular biology and medicine and relates to a method for detecting hypertension susceptibility genes and a detection kit thereof. The method for detecting the essential hypertension susceptibility genes comprises the step of detecting the gene type of the locus rs873457 of mitochondria fusion genes 2 (Mfn2) / hyperplasia suppressor genes (HSG) People having the locus rs873457 of the C gene type are more susceptible to the hypertension than the common crowd. The invention also discloses a relevant detection kit containing primers for amplifying the locus rs873457 and primers for amplifying a zone containing the locus rs873457 in the intron No.2 of the Mfn2 genes. The method is easy to operate, can be used for quickly and effectively detecting the genetype of the locus rs873457 and has low cost, thereby being a simple new method for diagnosing and treating the hypertension..

The invention belongs to the field of molecular biology and medicine, relating to a method for detecting a hypertension susceptibility gene and a detection kit thereof. The method for detecting a primary hypertension susceptibility gene comprises the following step of: detecting the genotype of the rs4846085 locus of a mitochondrion fusion gene 2(Mfn2) / a hyperplasia suppressor gene (HSG). The hypertension susceptibility of an rs4846085 individual with a genotype T is remarkably higher than that of the general public. The invention also discloses the corresponding detection kit. The detection kit contains a primer for amplifying the rs4846085 locus and can also contain the primer for amplifying a region comprising the rs4846085 locus in a third intron of the Mfn2 gene. The genotype of the rs4846085 locus is detected by adopting the method. The invention has simple and easy method, quick speed and high efficiency and low cost and provides a novel shortcut approach for diagnosing and treating hypertension.

The invention belongs to the field of molecular biology and medicine and relates to a method and a kit for detecting a susceptibility gene of hypertension. The invention provides a method for detecting a susceptibility gene of essential hypertension. The method comprises a step of detecting the gene type of a mitochondria fusion gene 2 (Mfn2) / hyperplasia suppressor gene (HSG) rs2878677 locus, wherein the hypertension susceptibility of an individual of which the rs2878677 locus carries a T gene type is obviously higher than that of common people. The invention also discloses a corresponding kit for detecting the susceptibility gene of hypertension. The kit comprises a primer for amplifying the rs2878677 locus and a primer for amplifying an area comprising the rs2878677 locus in the No.2 intron of Mfn2 gene. When used for detecting the gene type of the rs2878677 locus, the method is simple and is easy to implement, is fast and efficient, and has low cost and provides a simple and direct new way for the diagnosis and treatment of hypertension.

The invention belongs to the molecular biology and medicine field and relates to a method for detecting a susceptibility gene of hypertension and a detection kit thereof. The invention provides a method for detecting a susceptibility gene of essential hypertension, comprising the step of detecting the genetype of a mitochondrion fusion gene 2(Mfn2) / hyperplasia suppressor gene (HSG) locus rs2336384. The individual, rs2336384 of which carries the G genetype has obviously higher susceptibility of hypertension than the common people. The invention also discloses the corresponding detection kit which contains a primer amplifying the locus rs2336384 and a primer amplifying the region of the locus rs2336384 contained in the No.2 intron of the Mfn2 gene. Being used for detecting the genetype of the locus rs2336384, the method is simple and practicable, fast and efficient and low in cost and provides a simple and direct new way for hypertension diagnosis and treatment.

The invention belongs to the field of molecular biology and medicine and relates to a method for detecting susceptibility of essential hypertension and a kit thereof. The method for detecting the susceptibility of the essential hypertension comprises a step of detecting genotypes of mitochondrion fusion gene 2 (Mfn2) / hyperplasia suppressor gene (HSG) rs4240897 sites of an individual. For an individual of which the rs4240897 carries a G genotype, the susceptibility of hypertension of is obviously higher than that of general people. The invention further discloses a corresponding detection kit which contains a primer of which a No.2 amplification Mfn2 gene comprises a sub-area. By using the invention to detect the genotypes of the rs4240897 sites, the method is simple and easy, has a high speed, high efficiency and a low cost, and provides a new simple approach for hypertension diagnosis and treatment.

The invention belongs to the fields of molecular biology and medicine and relates to a method for detecting hypertension susceptibility genes and a detection kit thereof. The method for detecting the essential hypertension susceptibility genes comprises the step of detecting the gene type of the locus rs2236058 of mitochondria fusion genes 2 (Mfn2) / hyperplasia suppressor genes (HSG). People having the locus rs2236058 of the C gene type are more susceptible to the hypertension than the common crowd. The invention also discloses a relevant detection kit containing primers for amplifying the locus rs2236058 and primers for amplifying a zone containing the locus rs2236058 in the intron No.11 of the Mfn2 genes. The method is easy to operate, can be used for quickly and effectively detecting the gene type of the locus rs2236058 and has low cost, thereby being a simple new method for diagnosing and treating the hypertension.

The invention belongs to the molecular biology and medicine field and relates to a method for detecting a susceptibility gene of hypertension and a detection kit thereof. The invention provides a method for detecting a susceptibility gene of essential hypertension, comprising the step of detecting the genetype of a mitochondrion fusion gene 2(Mfn2) / hyperplasia suppressor gene (HSG) locus rs7550536. The individual, rs7550536 of which carries the T genetype has obviously higher susceptibility of hypertension than the common people. The invention also discloses the corresponding detection kit which contains a primer amplifying the locus rs7550536 and a primer amplifying the region of the locus rs7550536 contained in the No.14 intron of the Mfn2 gene. Being used for detecting the genetype of the locus rs7550536, the method is simple and practicable, fast and efficient and low in cost and provides a simple and direct new way for hypertension diagnosis and treatment.