34 results about "Cheyne-stokes breathing" patented technology

The present invention relates to a device and method for monitoring for sleep disordered breathing or other types of disordered breathing such as Cheyne-Stokes breathing. More specifically, a device and method for detecting disordered breathing is provided that monitors a physiological parameter, which becomes cyclical due to apnea-hyperpnea (or arousal) alternation and provides the basis for the determination of a number of breathing disorder metrics.

Method and apparatus for the treatment of cardiac failure, Cheyne Stokes breathing or central sleep apnea are disclosed. A subject is provided with ventilatory support, for example positive pressure ventilatory support using a blower and mask. Respiratory airflow is determined. From the respiratory airflow are derived a measure of instantaneous ventilation (for example half the absolute value of the respiratory airflow) and a measure of longterm average ventilation (for example the instantaneous ventilation low pass filtered with a 100 second time constant). A target ventilation is taken as 95% of the longterm average ventilation. The instantaneous ventilation is fed as the input signal to a clipped integral controller, with the target ventilation as the reference signal. The output of the controller determines the degree of ventilatory support. Clipping is typically to between half and double the degree of support that would do all the respiratory work. A third measure of ventilation, for example instantaneous ventilation low pass filtered with a time constant of 5 seconds, is calculated. Ventilatory support is in phase with the subject's respiratory airflow to the fuzzy extent that this ventilation is above target, and at a preset rate conversely.

Techniques are provided for treating periodic breathing, such as Cheyne-Stokes Respiration, using an implantable medical system. In one technique, diaphragmatic stimulation is delivered during a hyperpnea phase of periodic breathing via electrical stimulation of the phrenic nerves. Diaphragmatic stimulation is synchronized with intrinsic inspiration so as to increase the amplitude of diaphragmatic contraction during inspiration. This tends to decrease intrathoracic pressure leading to occlusion of the respiratory airway. Occlusion reduces actual ventilation during hyperpnea, thus reducing the cyclic blood chemistry imbalance that sustains periodic breathing so as to either mitigate periodic breathing or eliminate it completely. In another technique, respiration is instead inhibited during the hyperpnea phase of periodic breathing by blocking phrenic nerve signals to the extent necessary to reduce ventilation to terminate periodic breathing or at least mitigate its severity. Techniques are also described for controlling the type of therapy applied in response to periodic breathing.

A signal representative of a patient's respiration is split into equal length epochs. A primary feature is extracted from each epoch that acts as a compressed representation of the signal events. Statistics are applied to the primary feature to produce one or more secondary features that represent the entire epoch. Each secondary feature is grouped with one or more other features that are extracted from the entire epoch rather than selected epoch events. This grouping is the epoch pattern. The pattern is manipulated with suitable classifier algorithm to produce a probability for each class within the algorithm, that the signal may be representative of a disease state (Cheyne-Stokes, OSA etc). The epoch is assigned to the class with the highest probability. Also defined are methods of detecting Cheyne-Stokes breathing by analyzing a signal to detect one or regions of hyperpnoea and if the length of a hyperpnoea exceeds a parameter, Cheyne-Stokes is present.

The invention relates to a method and a device for treating Cheyne-Stokes respiration, periodic respiration and central or mixed apnea. If the respiration waxes and wanes periodically, there is pressure support in phases of periodic respiration, taking into account the natural patient respiration.