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Systems and methods for identifying personalized vascular implants from patient-specific anatomic data

a technology of anatomic image data and vascular implants, applied in the field of medical imaging, can solve problems such as heart attack, myocardial infarction, or restricted blood flow to the hear

Active Publication Date: 2019-11-28
HEARTFLOW
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Benefits of technology

The patent text describes a new invention and its technical effects. The technical effects of this patent are not restricted to the specific details mentioned, as they are only intended to explain the invention in a general way. The patent's goal is to enable a reader to understand the invention and its benefits without being limited to the specifics.

Problems solved by technology

As a result, blood flow to the heart may be restricted.
A more severe manifestation of disease may lead to myocardial infarction, or heart attack.

Method used

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  • Systems and methods for identifying personalized vascular implants from patient-specific anatomic data
  • Systems and methods for identifying personalized vascular implants from patient-specific anatomic data

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Embodiment Construction

[0016]Reference will now be made in detail to the exemplary embodiments of the invention, examples of which are illustrated in the accompanying drawings. Wherever possible, the same reference numbers will be used throughout the drawings to refer to the same or like parts.

[0017]A new generation of noninvasive tests have been developed to assess blood flow characteristics. These noninvasive tests use patient imaging (such as CT) to determine a patient-specific geometric model of the blood vessels, which may be used computationally to simulate the blood flow using computational fluid dynamics (CFD) with appropriate physiological boundary conditions and parameters. Examples of inputs to these patient-specific boundary conditions include the patient's blood pressure, blood viscosity and the expected demand of blood from the supplied tissue (derived from scaling laws and a mass estimation of the supplied tissue from the patient imaging).

[0018]The present disclosure is directed to noninvas...

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Abstract

Embodiments include methods of identifying a personalized cardiovascular device based on patient-specific geometrical information, the method comprising acquiring a geometric model of at least a portion of a patient's vascular system; obtaining one or more geometric quantities of one or more blood vessels of the geometric model of the patient's vascular system; determining the presence or absence of a pathology characteristic at a location in the geometric model of the patient's vascular system; generating an objective function defined by a plurality of device variables and a plurality of hemodynamic and solid mechanics characteristics; and optimizing the objective function using computational fluid dynamics and structural mechanics analysis to identify a plurality of device variables that result in desired hemodynamic and solid mechanics characteristics.

Description

PRIORITY[0001]This application claims the benefit of priority from U.S. Provisional Application No. 61 / 866,758, filed Aug. 16, 2013, which is herein incorporated by reference in its entirety.TECHNICAL FIELD[0002]Various embodiments of the present disclosure relate generally to medical imaging and related methods. More specifically, particular embodiments of the present disclosure relate to systems and methods for identifying personalized vascular devices from patient-specific anatomic image data.BACKGROUND[0003]Coronary artery disease may produce coronary lesions in the blood vessels providing blood to the heart, such as a stenosis (abnormal narrowing of a blood vessel). As a result, blood flow to the heart may be restricted. A patient suffering from coronary artery disease may experience chest pain, referred to as chronic stable angina during physical exertion or unstable angina when the patient is at rest. A more severe manifestation of disease may lead to myocardial infarction, o...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61F2/95G16H50/50G16H50/20G06T7/00G06K9/62A61B6/00A61B34/10
CPCA61F2/95G16H50/50G16H50/20G06F17/5009G06K9/6293A61B6/00A61B34/10G06T7/0012A61B2034/105A61B2034/107A61B2034/108A61B2090/3762A61F2002/30943A61F2240/004G06F30/20G06F18/256A61B5/0205A61B5/076A61B2576/023
Inventor GRADY, LEO J.TAYLOR, CHARLES A.CHOI, GILWOOROGERS, CAMPBELL
Owner HEARTFLOW
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