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Use and application of a pharmaceutical composition containing a mixture of natural- origin heterocyclical guanidine, for cosmetology, wound healing, focal dystonia and muscular spasm- related clinical pathologies

a technology of heterocyclic guanidine and composition, which is applied in the field of pharmaceutical compositions containing heterocyclic guanidinetype compounds, can solve the problems of social groups judging the appearance of wrinkles on the neck and face of people as negative, complicated use and handling, and less desirable effects

Inactive Publication Date: 2006-06-08
PHYTOTOX LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0011]FIG. 1 is an illustration of an application pattern for the treatment of a human face.

Problems solved by technology

The presence of wrinkles in the neck and face of people are seen as negative aesthetic effects by social groups.
While Botulin A toxin is effective as a facial rejuvenate, it is an enzyme that is inherently unstable.
This instability makes its use and handling complicated and less desirable.
In fact, it requires freezing before using and must be used within four hours of opening the container.
In addition, its results are delayed 7-10 days, which is undesirable for patients wanting an immediate result.

Method used

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  • Use and application of a pharmaceutical composition containing a mixture of natural- origin heterocyclical guanidine, for cosmetology, wound healing, focal dystonia and muscular spasm- related clinical pathologies
  • Use and application of a pharmaceutical composition containing a mixture of natural- origin heterocyclical guanidine, for cosmetology, wound healing, focal dystonia and muscular spasm- related clinical pathologies

Examples

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example

[0022] Before the application, a photographic record is made of the person to be treated, first with her face resting and relaxed, and then, frowning and producing a maximum facial contraction. The person then places ice on their forehead and on the two lateral zones where the preparation is to be injected. With reference to FIG. 2, the application should follow a specific pattern. A volume is injected alongside each black-dot injection point shown in FIG. 2. A pharmaceutical composition comprising a (2:1:1 volume / volume) mixture of Gonyautoxin 2, Gonyautoxin 3 and Saxitoxin mixture is applied at a dose of 40 units / milliliter. Each injection is made with a 1 milliliter, tuberculin-type disposable syringe with a 27-30 gauge needle. After injecting, the point of injection is disinfected with a gauze soaked in bi-alcohol or in any other disinfectant. The total amount required to complete the face treatment is 1.7 milliliters.

[0023] The expected result is an immediate inability to frow...

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Abstract

Pharmaceutical compositions comprising tricyclic 3,4-propinoperhydropurines and uses thereof for blocking neuronal transmission are provided.

Description

CROSS REFERENCE TO RELATED APPLICATIONS [0001] This application claims priority under the Paris Convention for the Protection of Industrial Property to Chilean Patent Application Number 2764-2001, filed on Nov. 15, 2001 in the Department of Industrial Property in the Republic of Chile. STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT [0002] Not applicable. REFERENCE TO MICROFICHE APPENDIX [0003] Not applicable. FIELD OF THE INVENTION [0004] This invention relates to pharmaceutical compositions containing heterocyclic guanidine-type compounds and uses thereof for blocking neuronal transmission. More specifically, this invention relates to tricyclic 3,4-propinoperhydropurines and uses thereof for blocking neuronal transmission. BACKGROUND OF THE INVENTION [0005] The presence of wrinkles in the neck and face of people are seen as negative aesthetic effects by social groups. These marks reflect face aging and increase the subjective awareness of the age of people. Since t...

Claims

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Application Information

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IPC IPC(8): A61K31/519A61KC07D473/32A61K9/08A61K9/10A61K31/505A61K31/52A61K35/74A61K38/00A61K38/48A61K47/04A61K47/12A61P17/00A61P21/02A61P25/00C07D
CPCA61K31/519A61K31/52A61K38/4886A61K2300/00A61K31/495A61K31/40A61K31/4168A61P1/00A61P13/10A61P17/00A61P17/02A61P21/00A61P21/02A61P25/00A61P27/02A61P29/00
Inventor WILSON, NESTOR ANTONIO LAGOS
Owner PHYTOTOX LTD
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