Wound healing composition and method for use thereof

Abstract

A method for reducing or preventing the formation of scar tissue is disclosed. The method comprises applying a pharmacologically effective amount of a composition comprising about 5.0% by weight of ovalbumin, about 1.0% phenoxyethanol, about 0.5% carbomer, and about 0.3% triethanolamine. A method for stimulating fibroblast production is also disclosed. The method comprises applying a pharmacologically effective amount of a composition comprising about 5.0% by weight of ovalbumin, about 1.0% phenoxyethanol, about 0.5% carbomer, and about 0.3% triethanolamine.

Description

FIELD OF THE INVENTION [0001] This invention pertains to wound healing compositions and, particularly, to such a composition comprising of a growth hormone and growth factor in a balanced mixture that will deliver the maximum therapeutic results with non-healing wounds, burns, trauma, and certain dermatological disorders. BACKGROUND OF THE INVENTION [0002] 1. Overview of the Invention [0003] There have been recent dramatic strides with the discovery of growth factors as wound healing agents. Indeed, the discovery of growth factors has triggered great optimism into the possibility of mastering the art of wound healing and intense effort has been launched on the part of medical researchers and pharmaceutical companies to procure, characterize, and harvest these healing enhancement agents. Because it is believed that administering growth factors to patients with dermal and subdermal wounds enhances the speed by which wounds heal, as discussed in greater detail below, it is the object o...

AI Technical Summary

Benefits of technology

[0016] In accordance with the present invention, it has now been discovered that wounds may be effectively treated with the growth factors that are contained in egg whites of hens. Specifically, topically administered growth factors in pharmacologically effective amounts are useful for increasing the local activity of the body's wound healing process. Accordingly, the present invention is a low cost, over-the-counter, composition containing growth factors isolated from a naturally occurring source—egg whites. The composition may be used to treat any disease state where growth factors play a role including diabetic ulcers, nonhealing wounds, burns, osteomyelitis, trauma wounds, subcutaneous trauma and various forms of dermatitis.

[0020] It is another object of the present invention to treat wounds with a topical agent that is easily administered, economical and well-tolerated by patients.

Problems solved by technology

Studies have shown that fluid factors isolated from chronic wounds lack the presence of growth factors.

In contrast, the addition of partially purified PDGF results in significant dose-dependent increases in the width of the newly synthesized connective tissue and epidermal layers.

Further, the addition of partially purified PDGF results in significant increases in the rate of protein and DNA synthesis and the total content of these components in biopsies taken from the wound site.