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Moisturizing eye drop and preparation process therof

A preparation process, a technology for moisturizing eye lotion, applied in sensory diseases, pharmaceutical formulations, drug combinations, etc., can solve problems such as inability to achieve prevention and good preventive effects, promote vascular endothelial growth, avoid secondary pollution, and strengthen. moisturizing effect

Inactive Publication Date: 2007-05-23
SHANGHAI QISHENG BIOLOGICAL PREPARATION CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these are very necessary, they cannot achieve prevention and a good preventive effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0031] The preparation process of a Yanshukang moisturizing eye liquid preparation is all operated under the local class 100 condition of a 10,000-class clean room, and the process is as follows:

[0032] The first step. Add 98.535 parts of water for injection in the container, and its preparation concentration is 0.7 part of sodium chloride, 0.015 part of sodium dihydrogen phosphate, and 0.2 part of disodium hydrogen phosphate, and prepares a buffer solution;

[0033] Step 2. After it is completely dissolved, add sodium hyaluronate with a concentration of 0.05 parts and chitosan with a concentration of 0.5 parts, and stir to completely dissolve;

[0034] Step 3. Filtration of the product

[0035] (1). Connect the sterilized 0.22 μm filter to the filter press barrel, pour the clarified product into the filter press barrel, and quickly put the filter outlet into the glass bottle for collecting the sterilizing solution;

[0036] (2). Opening pressure for sterilization and filtr...

example 2

[0044]Case 2: Wang Moumou, male, 64 years old, retired doctor. Complaints of dry eyes and itching for more than 2 years, often dryness, occasional foreign body sensation, eyelid adhesion and a small amount of discharge in the morning, no burning sensation or pain (clinical performance score is 2 points). Physical examination revealed conjunctival hyperemia and conjunctival accumulation, Schirmer-I test and BUT were lower than normal; fluorescein staining left and right eyes both scored 2, and there were more staining points in the third and fourth quadrants of the cornea of ​​both eyes; tiger red Both left and right eyes were stained with a score of 4.5, and there were slightly dense staining spots in the middle and lower parts of both eyes. The clinical diagnosis was dry eye syndrome, and he was treated with Yanshukang Moisturizing Eye Solution 0.4ml qid. Thirty days later, the patient complained that the symptoms of dry itching in the eyes had improved significantly, the fo...

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PUM

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Abstract

The invention relates to a method for preparing eyedrops, wherein the invention is characterized in that: adding 98.0-99.2% injection water into container, 5-10%.common salt, 0.1-0.2%. acid sodium phosphate, 1-3%. acid sodium phosphate, to prepare buffer liquid; when they are dissolved completely, adding 0.01-0.10% hyaluronic acid, 0.10-1.00% chitosan, mixing; using 0.22 mum filter element to disinfect and filter in multistage room, using machine to automatically pack. The invention can accelerate the growth of epithelial cell, and it will not flow into nasal. It not contains conservative and antibacterial agent.

Description

technical field [0001] The invention relates to a Yanshukang eye-moisturizing liquid preparation and its preparation process, which is suitable for dry eye patients, Or contact lens wearers directly drop their eyes before or after wearing contact lenses to relieve discomfort such as eye dryness and eye fatigue, and belong to the technical field of eye drops. Background technique [0002] At present, for eye care, one is to use various eye drops and eye ointments for targeted treatment when the eyes suffer from various diseases; waiting. Although these are all very necessary, they cannot achieve prevention and a good preventive effect. Eye protection, especially eye care and care should be paid attention to at ordinary times. It is obvious that prevention is better than cure, and it is also the key to the rapid development of health care medicine today. Contents of the invention [0003] The object of the present invention is to provide a Yanshukang eye-moisturizing liqu...

Claims

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Application Information

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IPC IPC(8): A61K31/722A61K31/728A61K9/08A61P27/02
Inventor 顾其胜
Owner SHANGHAI QISHENG BIOLOGICAL PREPARATION CO LTD
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