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Animal medicament with anthemorrhagic toxin-removing and dysentery-eliminating functions and its preparation

A detoxification function, astringent and hemostasis technology, which is applied to veterinary medicines with antidiarrheal and detoxification functions. The traditional Chinese medicinal material Agrimony Root is used as raw material to prepare a kind of astringent hemostasis field, which can solve the problems of strong odor, high cost, uneconomical medicine for livestock and poultry, etc.

Inactive Publication Date: 2007-04-04
TIANJIN RINGPU BIO TECH
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AI Technical Summary

Problems solved by technology

[0004] In the course of clinical use, due to modern large-scale breeding, directly mixing the raw materials of traditional Chinese medicines for administration often causes problems such as inconvenient administration, strong odor, and low absorption rate, so that the medicinal effect of Agrimony can not be fully exerted, and as in 2005 The "Compound Agrimony Enteritis Capsules" preparation in the "Pharmacopia of the People's Republic of China" in 2011 is extracted by the commonly used boiling and alcohol precipitation method, which not only loses a lot of active ingredients, but also wastes a lot of ethanol
At present, the application of Agrimony powder in livestock and poultry diseases has not yet been retrieved. Agrimony is mainly used to treat hemoptysis, hematemesis, carbuncle and sore for human use. The extraction technology is also the extraction technology of human medicine, which is complex and costly. High, it is not economical to use for livestock and poultry medicine; and the above-mentioned extraction process often removes nutrients such as protein in traditional Chinese medicine, which virtually increases the cost of livestock and poultry breeding

Method used

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Experimental program
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Effect test

Embodiment 1

[0026] Embodiment 1: Take Agrimony medicinal material 100kg, wash Agrimony raw material as required, pick up, cut, dry, pulverize and pass through a 60-mesh sieve for later use. The extraction temperature is 95±3°C, the amount of water added for the first time is 8 times of the weight of the medicinal materials, the pH is adjusted to 3 with 10% acid, and the extraction time is 2 hours; the amount of water added for the second time is still 8 times of the weight of the medicinal materials, and 10% alkali was used to adjust the pH to 8.5, and the extraction time was 1 hour. The concentration temperature is 80°C, the vacuum degree is -0.09Mpa, and the specific gravity is 1.30g / cm 3 (80°C). Spray-dry or dry under reduced pressure in a vacuum and then pulverize to obtain Agrimony powder 15.2kg (yield: 15.2%).

[0027] Chicken flocks in a chicken farm were infected with leukocytozoon disease. Most of the flocks suffered from mental sluggishness, loss of appetite, pale combs, loose...

Embodiment 2

[0028]Embodiment 2: get Agrimony medicinal material 100kg, preparation method is the same as embodiment 1. After extraction, Agrimony powder 16.7kg (yield: 16.7%) can be obtained. Piglets in a pig farm were infected with piglet red scour, manifested as bloody stools, lack of energy, loss of appetite, etc. The severity of the disease was different. Add medicine of the present invention in the feed, 0.8g / kg feed, use continuously 5 days. After 5 days, the condition of most of the sick pigs began to improve gradually, and they began to eat and drink normally. After continuing to consolidate the treatment, he was basically fully recovered.

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Abstract

A veterinary medicine with the functions of stypsis, haemostasis, treating dycentery and detoxication for treating the epidemic diseases of domestic animals and fowls is prepared from grinony root through pre-treating, decocting in water for 2 hr while using acid to regulate pH=2-5, filtering, decocting again for 1.5 hr while using alkali to regulate pH=8-9, filtering, collecting the decoction, drying and pulverizing.

Description

technical field [0001] The present invention relates to the technical field of medical preparations (International Patent Classification No. 35 / 79) derived from plants and containing reaction products of unknown structure. Functional veterinary medicine and its preparation method. Background technique [0002] Chinese medicine is one of the important components in the treasure house of Chinese medical culture, and Chinese herbal medicine is a cultural treasure of our country. In terms of animal medicine, traditional Chinese veterinary medicine also plays a very important role in the diagnosis and treatment of livestock and poultry diseases. [0003] Agrimony (synonymously named Longya grass, Shizhou Longya grass, from "The Classic of Materia Medica"; melon vanilla, from "Rescue Famine Materia Medica") is one of the commonly used medicinal materials for detoxification and dysentery in veterinary traditional Chinese medicine. Modern research on its pharmacological effects : ...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61K9/14A61P7/04A61P1/12
Inventor 李旭东鲍恩东苏建东
Owner TIANJIN RINGPU BIO TECH
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