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Medical usage of periplocin A and E

A kind of technology of baricolidin and its chemical composition, which is applied in the field of medical application of baricacids A and E, and can solve the problems such as the undiscovered natural product baricacid

Inactive Publication Date: 2007-04-04
SHANGHAI INST OF MATERIA MEDICA CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] So far, there is no report on the immunosuppressive activity of the natural products salivaside A and E

Method used

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  • Medical usage of periplocin A and E
  • Medical usage of periplocin A and E
  • Medical usage of periplocin A and E

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1 Immunosuppressive effect of the active ingredient barley glycoside E in Acanthopanax acanthus

[0020] 1. Experimental materials

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Abstract

A medical application of periplocoside A and E in preparing the immunodepress ant with high effect and low poison is disclosed.

Description

technical field [0001] The present invention relates to the pharmaceutical application of natural products saccharosides A and E, in particular, the invention relates to the use of natural products scorpiosides A and E for preparing immunosuppressive drugs. Background technique [0002] Immunosuppressor (immunosuppressor) is a drug that has a suppressive effect on immunity. Different specific drugs act on different links of immune response and regulation. It is mainly used clinically to treat autoimmune diseases and prevent organ transplant rejection. Immunosuppressants are mainly divided into the following categories: (1) Chemical agents, such as nitrogen mustards of alkylating agents. (2) Hormones, such as glucocorticoids. (3) Fungal metabolites, such as cyclosporin A (cyclosporin A, CsA). (4) Traditional Chinese medicine and its active ingredients. [0003] Most immunosuppressive drugs have obvious side effects, mainly bone marrow suppression, liver and kidney toxicit...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61P37/06A61P37/02A61P3/10A61P1/00A61P1/16A61P7/00A61P17/00A61P21/04
CPCA61K31/7048A61P1/00A61P1/16A61P3/10A61P7/00A61P17/00A61P21/04A61P37/02A61P37/06A61P37/08
Inventor 赵维民左建平刘群芳朱一娜邹健杨以阜田佳周宇
Owner SHANGHAI INST OF MATERIA MEDICA CHINESE ACAD OF SCI
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