Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Determination of Chinese patent drug Chinese magnoliavine fruit content made from Chinese magnoliavine fruit extract

A technology of schisandrin and southern schisandrin, which is applied in the field of determination of schisandrin content, can solve the problems of easy introduction of errors, long measurement time, inaccurate results, etc., and achieve the effect of high sensitivity and small error

Inactive Publication Date: 2007-01-17
SICHUAN HEZHENG PHARM CO LTD
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The specificity of this method is not strong, and the maximum absorption wavelength of ultraviolet scanning of test product is inconsistent with the maximum absorption wavelength 222nm of schisandrin and differs greatly, and the maximum absorption wavelength of ultraviolet scanning of each batch of test products is not completely consistent; and The preparation of the test solution in this method is cumbersome, the measurement time is long, errors are easily introduced, and the results are inaccurate

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Determination of Chinese patent drug Chinese magnoliavine fruit content made from Chinese magnoliavine fruit extract
  • Determination of Chinese patent drug Chinese magnoliavine fruit content made from Chinese magnoliavine fruit extract
  • Determination of Chinese patent drug Chinese magnoliavine fruit content made from Chinese magnoliavine fruit extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] Determination of Schisandrin A Content

[0030] The conditions of ultrasonic treatment mentioned below are power 250W, frequency 40KHz

[0031] 1. Instruments and reagents

[0032] Instrument: Shimadzu LC-2010A HT Liquid Chromatograph

[0033] Sample: the large-scale production of capsules made from twenty-three batches of Schizandra chinensis alcohol extract provided by Sichuan Hezheng Pharmaceutical Co., Ltd. Appropriate amount of starch and other auxiliary materials, mixed evenly, made into granules, dried, packed into capsules, made into 1000 capsules) The batch numbers are: 031102, 031112, 040708, 040710, 040801, 040802, 040807, 040902, 040903, 041002, 041003, 041007 , 041008, 041101, 041108, 041203, 041204, 041206, 050101, 050103, 050406, 050407, 050408

[0034] Reagents: Methanol and acetonitrile are chromatographically pure, water is double distilled water, and others are analytically pure

[0035] Reference substance: Schizandrin A was provided by China Ins...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
separationaaaaaaaaaa
separationaaaaaaaaaa
separationaaaaaaaaaa
Login to View More

Abstract

A method for measuring the content of schizandrin A in the Chinese medicine prepared from the alcohol extract of schisandra fruit includes such steps as experiment of chromatographic condition and system adaptivity, preparing the solution of reference, preparing the solution of specimen, and measuring.

Description

technical field [0001] The invention relates to a method for determining the content of schisandrin, in particular to a method for determining the content of schisandrin in finished medicine made from schisandrin extract. Background technique [0002] Schisandra chinensis (formerly known as Schisandra chinensis) is decocted with water, the dregs are dried, crushed, and extracted with 70% ethanol under reflux to obtain alcoholic extract of Schisandra chinensis. The finished medicines further made from the extract of Schisandra chinensis include capsules, tablets, dropping pills, powders, etc. The Chinese patent medicine can reduce serum alanine aminotransferase, and can be used for patients with chronic and persistent hepatitis with elevated alanine aminotransferase. Modern studies have shown that the active ingredients in Schisandra chinensis with liver protection and enzyme-lowering effects are lignans, mainly including schisandrin A and schisandra ester A. [0003] The d...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/57G01N30/02
Inventor 吴克勤许邑
Owner SICHUAN HEZHENG PHARM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com