Medicinal composition for preventing or treating metabolic syndrome
A pharmaceutical preparation and preparation technology, applied in the field of pharmacy, can solve the problems of vitamin folic acid deficiency, elevated plasma homocysteine, Hcy accumulation, etc.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0043] Embodiment 1 prepares compound metformin folic acid (0.4mg) sheet (1000 pieces amount)
[0044] Formula: Metformin 250g
[0045] Folic acid 0.4g
[0046] Starch 100g
[0047] Microcrystalline Cellulose 50g
[0048] Sodium carboxymethyl starch 20g
[0049] Low-substituted hydroxypropyl cellulose 20g
[0050] Proper amount of povidone ethanol solution
[0052]Preparation method: crush the raw and auxiliary materials through an 80-mesh sieve, and dry for later use. Take 250g of metformin and 0.4g of folic acid and mix them uniformly according to the method of equal increase, add starch, microcrystalline cellulose, sodium carboxymethyl starch and low-substituted hydroxypropyl cellulose respectively according to the prescription amount, mix evenly according to the method of equal increase, and use 5% povidone K29 / 30-95% ethanol solution to make soft material, granulate with 20-mesh sieve, dry at 40°C for about 2 hours, granulate with 20-...
Embodiment 2
[0053] Embodiment 2 prepares compound metformin folic acid (0.8mg) sheet (1000 pieces amount)
[0054] Formula: Metformin 250g
[0055] Folic acid 0.8g
[0056] Starch 100g
[0057] Microcrystalline Cellulose 50g
[0058] Sodium carboxymethyl starch 20g
[0059] Low-substituted hydroxypropyl cellulose 20g
[0060] Proper amount of povidone ethanol solution
[0062] The preparation method is the same as that in Example 1, and each of the prepared compound tablets contains 250 mg of metformin and 0.8 mg of folic acid, with a mass ratio of 250:0.8.
Embodiment 3
[0063] Embodiment 3 prepares compound metformin folic acid (1.0mg) sheet (1000 pieces amount)
[0064] Formula: Metformin 250g
[0065] Folic acid 1.0g
[0066] Starch 100g
[0067] Microcrystalline Cellulose 50g
[0068] Sodium carboxymethyl starch 20g
[0069] Low-substituted hydroxypropyl cellulose 20g
[0070] Proper amount of povidone ethanol solution
[0072] The preparation method is the same as that in Example 1, and each of the prepared compound tablets contains 250 mg of metformin and 1.0 mg of folic acid, with a mass ratio of 250:1.
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com