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Herba thesii granules and preparing method therefor

The technology of granules and balsamina is applied to the new dosage form of balsamina granules and the field of preparation thereof, which can solve the problems of patients who are not easy to take with stomach diseases, patients who are not easy to take children, and enhance irritation, so as to improve bioavailability and promote rapid recovery. , the effect of convenient use

Inactive Publication Date: 2006-10-25
管悦琴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the capsule dosage form is not easy to take, especially for children, and after the capsule dissolves in the stomach, the local concentration is too high, which increases the irritation, so it is not easy for patients with severe stomach problems to take it.

Method used

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  • Herba thesii granules and preparing method therefor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] A barley granule comprises the main material barley grass and auxiliary materials dextrin, sucrose and ethanol. The preparation method of Bairui granule is prepared according to the following steps:

[0070] (1) According to the medicinal material extract: the auxiliary material is 1:5, take 1200g of thyme grass and add water to decoct twice, add 12 times the amount of water for the first time, soak for 2 hours, decoct for 2 hours, and add 10 times for the second time Measure water and boil for 1.5 hours;

[0071] (2) Filter the decoction, combine the filtrates, concentrate under reduced pressure to a relative density of 1.22-1.24 (80°C), and let cool;

[0072] (3) Add 75% ethanol and stir well; then add an equal amount of ethanol and stir well;

[0073] (4) After standing still for 12 hours, filter the supernatant, recover ethanol, concentrate under reduced pressure to a thick paste with a relative density of 1.35-1.39 (80°C);

[0074] (5) Take another appropriate a...

Embodiment 2

[0076] A barley granule comprises the main material barley grass and auxiliary materials dextrin, sucrose and ethanol. The preparation method of Bairui granule is prepared according to the following steps:

[0077] (1) According to the medicinal material extract: auxiliary materials are 1:2, take 2400g thyme grass and add water to decoct twice, add 12 times the amount of water for the first time, soak for 2 hours, decoct for 2 hours, and add 10 times for the second time Measure water and boil for 1.5 hours;

[0078] (2) Filter the decoction, combine the filtrates, concentrate under reduced pressure to a relative density of 1.22-1.24 (80°C), and let cool;

[0079] (3) Add 75% ethanol and stir well; then add an equal amount of ethanol and stir well;

[0080] (4) After standing still for 12 hours, filter the supernatant, recover ethanol, concentrate under reduced pressure to a thick paste with a relative density of 1.35-1.39 (80°C);

[0081] (5) Take another appropriate amount...

Embodiment 3

[0083] A barley granule comprises the main material barley grass and auxiliary materials dextrin, sucrose and ethanol. The preparation method of Bairui granule is prepared according to the following steps:

[0084] (1) According to the medicinal material extract: the auxiliary material is 1:5, take 1200g of thyme grass and add water to decoct twice, add 10 times the amount of water for the first time, soak for 2 hours, decoct for 2 hours, and add 8 times for the second time Measure water and boil for 1.5 hours;

[0085] (2) Filter the decoction, combine the filtrates, concentrate under reduced pressure to a relative density of 1.22-1.24 (80°C), and let cool;

[0086] (3) Add 60% ethanol, stir well; then add the same amount of ethanol, stir well;

[0087] All the other are with embodiment 1.

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Abstract

The present invention relates to a thesium Chinese granule preparation and its preparation method. It includes main raw material thesium Chinese and auxiliary material according to the mixing ratio of 1:1-1:2. Its auxiliary material includes excipient dextrin, stevioside or cane sugar as sweetener, and ethyl alcohol as lubricating agent and adhesive.

Description

technical field [0001] The invention relates to a new dosage form of a Chinese patent medicine and a preparation method thereof, in particular to a new dosage form of Bailicao granules and a preparation method thereof. Background technique [0002] Surveys in recent years have shown that there are 4 million cases of community-acquired pneumonia in the United States in one year, and more than 75% of prescriptions for respiratory infections are anti-infective drugs. Because the drug resistance of respiratory pathogens caused by medication is very prominent, the drug resistance of macrolides and first-generation cephalosporins has become more and more serious. In the late 1990s, it was as high as 34.7%, and 13.5% were highly resistant; the Streptococcus pneumoniae resistant to penicillin (MIC>2μg / mL), and resistant to cefotaxime was as high as 81.9%. Therefore it is very important to develop new drugs for the treatment of respiratory infections. Modern pharmacological resea...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/16A61P11/00A61P11/02A61P11/04A61P29/00A61P31/00
Inventor 管悦琴
Owner 管悦琴
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