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Making method of and use of antibiotic surgical dressing

A manufacturing method, chitosan fiber technology, applied in medical science, bandages, absorbent pads, etc., can solve the problems of accelerated wound healing, residual floc can not be absorbed by the body, no accelerated healing, etc., to achieve the purpose of improving strength and antibacterial effect Effect

Inactive Publication Date: 2006-09-20
李毅彬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this invention can only achieve the purpose of accelerating wound healing by providing a moist environment. It does not have the effect of accelerating wound healing itself, and the residual flakes left on the wound surface cannot be absorbed by the human body.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Immerse 100 grams of chitosan fiber in 45% NaOH solution, bath ratio 1: 20, react at room temperature for 4 hours, generate alkalized chitosan fiber, react this product with chloroacetic acid in isopropanol, the concentration of chloroacetic acid 25%, the reaction temperature is 60° C., and the reaction time is 6 hours. After the reaction is completed, the excess solution is removed, washed with absolute ethanol, and air-dried to obtain carboxymethyl chitosan fiber. This product is made into 50 g / m by opening, netting and needle punching 2 The dressing can be cut, packaged and sterilized. Suitable for wounds less than 10cm 2 the wound.

Embodiment 2

[0022] See Example 1 for the preparation method of carboxymethyl chitosan fiber. According to 8:2, chitosan fiber and carboxymethyl chitosan fiber are mixed, opened, netted and needle punched to make 100 g / m 2 The dressing can be cut, packaged and sterilized. It is suitable for burns and scalds with relatively large trauma.

Embodiment 3

[0024] See Example 1 for the preparation method of carboxymethyl chitosan fiber. Mix chitosan fiber and carboxymethyl chitosan fiber according to the ratio of 8:2, open and form into balls to make 0.2 g wound hemostatic and anti-inflammatory cotton balls.

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PUM

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Abstract

An antibacterial medical dressing for the operation wound is prepared from chitosan fibers through alkalizing to become alkaline chitosan fibers, and etherifying reaction on chloroacetic acid to become carboxymethyl chitosan fibers. When said fibers are encountered with water, it is swelling to become elastic gel. It is possible to add additive for higher curative effect.

Description

technical field [0001] The invention relates to a medical dressing, in particular to a medical dressing containing carboxymethyl chitosan fiber. Background technique [0002] For a long time, surgical dressings are mainly sterilized cotton and cotton gauze, which have certain limitations in their application. Cotton gauze itself does not have the ability to resist the reproduction of microorganisms. Although it has been sterilized, it is easy to be infected with bacteria during use. These traditional dressings will adhere to the wound during use, and even grow in the new granulation, causing pain to the patient and the generation of new wounds during dressing replacement. These traditional dressings also leave some debris after use, which affects wound healing. Dressings made of other synthetic materials suffer from the same drawback. [0003] When treating chronic wounds, a dressing is needed to absorb a large amount of exudate from the wound and at the same time acceler...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/42
Inventor 吴清基李毅彬成立萍
Owner 李毅彬
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