Medicine for treating glycuresis retinal disease and its prepn. method

A technology for a drug and an API is applied in the field of drugs for the treatment of diabetic retinopathy and its preparation, and can solve the problems of destroying the treatment method, unsatisfactory curative effect, limited indications and the like

Active Publication Date: 2006-09-20
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although many drugs have been used to treat DR, the efficacy of the above drugs is not satisfactory, and some drugs are contraindicated for patients with bleeding
In addition, there are laser photocoagulation, vitrectomy and other methods for the treatment of diabetic retinopathy, but the indications are limited, and after all, it is a destructive treatment method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] 188 parts of red peony root, 282 parts of astragalus, 188 parts of Rehmannia glutinosa, 141 parts of Puhuang, 188 parts of Ligustrum lucidum

[0042] Molian grass 188 parts Ginkgo biloba 282 parts Rhubarb 94 parts Panax notoginseng 94 parts Earthworm 94 parts

[0043] Cassia seed 282 parts Pueraria 188 parts

[0044] Preparation:

[0045] 1. Weigh Puhuang in proportion, use 6 times the amount of 70% ethanol as the solvent, first soak the medicinal materials with an appropriate amount of solvent, seal for 15 minutes, install the percolation column, add the remaining solvent to soak for 24 hours, and use about 3ml / kg / min Speed ​​percolation, collect percolate, and reserve.

[0046] 2. Weigh Rehmannia glutinosa and Earthworm in proportion, add 9 times the amount of water for the first time, soak for 20 minutes, heat and decoct for 1.5 hours, and filter; add 7 times the amount of water for the second time, decoct for 1.5 hours, filter, and filtrate Combine, concentrate to a rel...

Embodiment 2

[0054] 150 parts of Red Peony Root 250 parts of Radix Astragali 150 parts of Rehmannia Root 100 parts of Typhae Typhae

[0055] 150 parts of Molian grass 250 parts of Ginkgo biloba 50 parts of Rhubarb 50 parts of Panax notoginseng 50 parts of Earth Dragon 50 parts

[0056] Cassia seed 250 parts Pueraria lobata 150 parts

[0057] Preparation method: same as the steps 1), 2), 3), 4), 5), and 6) in Example 1, and prepare tablets according to the conventional method.

Embodiment 3

[0059] 250 parts of red peony root 350 parts of astragalus 250 parts of Rehmannia glutinosa 200 parts of Ligustrum lucidum 250 parts

[0060] Molian grass 250 parts Ginkgo biloba 350 parts Rhubarb 150 parts Panax notoginseng 150 parts Earthworm 150 parts

[0061] 350 servings of Cassia Seed 250 servings of Pueraria

[0062] Preparation method: same as the steps 1), 2), 3), 4), 5), and 6) in Example 1, and prepare pellets according to the conventional method.

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PUM

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Abstract

A Chinese medicine for treating diabetic retinopathy is prepared from 12 Chinese-medicinal materials including red peony root, astragalus root, rehmannia root, rhubarb, notoginseng, etc.

Description

Technical field [0001] The invention relates to a medicine for treating diabetic retinopathy and a preparation method thereof, and belongs to the technical field of Chinese herbal medicine preparations. Clinically, it is mainly used to treat diabetic retinopathy, such as retinal microangioma, hemorrhage, hard exudation, soft exudation, and retinal neovascularization in the fundus. Background technique [0002] There are 30 million people with diabetes in my country, and there are about 120 million people worldwide. According to the latest WHO data, the number of people with diabetes in China will reach four times the current number by 2010, and there will be 240 million people with diabetes in the world. The results of the epidemiological survey of diabetes in the Western Pacific region show that the westernization of people’s lives is an important factor in the increase in the incidence of diabetes, and non-insulin-dependent diabetes mellitus reaches 5-10% of people over 40. Alt...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61K9/08A61K9/10A61K9/20A61K9/48A61P27/02A61P3/10A61K35/64A61K35/62
Inventor 吴以岭
Owner SHIJIAZHUANG YILING PHARMA
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