Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases

A technology of immune regulation and compounds, applied in the direction of active ingredients of heterocyclic compounds, etc., can solve problems such as cancer that is difficult to cure

Inactive Publication Date: 2006-08-23
CELGENE CORP
View PDF38 Cites 12 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because of this drug resistance, many cancers prove refractory to standard chemotherapy

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases
  • Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases
  • Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] A first embodiment of the present invention includes a method of treating, treating or preventing cancer comprising administering to a patient in need of such treatment or prophylaxis a therapeutically or prophylactically effective amount of an immunomodulatory compound of the present invention, or a pharmaceutically acceptable Salts, solvates, hydrates, stereoisomers, inclusions or prodrugs.

[0023] In specific methods of this embodiment, the immunomodulatory compound is administered in combination with another drug ("second active agent") or method of treating, treating or preventing cancer. Second active agents include small and macromolecules (eg, proteins and antibodies, examples of which are provided here), as well as stem cells. Methods or therapies that may be employed when administering an immunomodulatory compound include, but are not limited to, surgery, blood transfusion, immunotherapy, biological therapy, radiation therapy, and other non-drug methods current...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Methods of treating, preventing and / or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combination with a second active ingredient. The invention further relates to methods of reducing or avoiding adverse side effects associated with chemotherapy, radiation therapy, hormonal therapy, biological therapy or immunotherapy which comprise the administration of an immunomodulatory compound. Pharmaceutical compositions, single unit dosage forms, and kits suitable of ruse in methods of the invention are also disclosed.

Description

1. Field of invention [0001] The present invention relates to methods of treating, preventing and / or managing cancer and other diseases, including but not limited to those associated with unwanted angiogenesis, by administering one or more immunomodulatory compounds alone or in combination with other therapies disease of or characterized by it. In particular, the invention includes the use of specific combinations or "cocktails" of drugs or other therapies, such as radiation therapy, to treat these specific cancers, including those that do not respond to conventional therapies. The invention also relates to pharmaceutical compositions and regimens. 2. Background of the invention [0002] 2.1 Pathology of cancer and other diseases [0003] The main features of cancer are an increase in the number of abnormal cells derived from a normal tissue, the invasion of adjacent tissues by these abnormal cells, or the spread of malignant cells to local lymph nodes and distant sites th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/44
Inventor 杰罗米·B·杰奥迪斯
Owner CELGENE CORP
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com