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Chinese medicinal composition for treating gout and its preparing process

A technology of composition and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine composition and preparation for the treatment of gout, and can solve the problems of poor curative effect, toxic side effects, etc.

Inactive Publication Date: 2006-07-19
GUIYANG XINTIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs have defects in treatment, poor curative effect, and obvious side effects, such as fever, allergic rash, abdominal pain, diarrhea, leukopenia and thrombocytopenia, and even liver and kidney function damage, etc., which have become the bottleneck of their clinical application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The preparation of embodiment 1 granule

[0034] formula:

[0035] Fenji 300g Phellodendron 200g Qinpi 200g

[0036] Smilax 400g Alisma 300g Plantain 400g

[0037] Pittosporum peel 300g Achyranthes bidentata 300g Rhubarb 100g

[0038] Preparation:

[0039] Soak the five flavors of medicinal materials such as Fenji, Phellodendron, Chinpi, Alisma, Pittodia, with 8 times the amount of 70% ethanol for 1 hour, then reflux extraction for 2 hours, and then add 8 times the amount of 70% ethanol for 2 hours , Combine the two reflux liquids, and filter to obtain the ethanol extract. Soak the four medicinal materials such as Smilax smilax, plantain, Achyranthes bidentata, and rhubarb in water for 1 hour, then add ethanol to extract the medicinal residues and decoct, add 12 times the amount of water each time, decoct 3 times, 2 hours each time . Combine the water decoctions, filter, concentrate the filtrate to a clear paste with a relative density of 1.06, add ethanol until ...

Embodiment 2

[0040] Example 2 Tablet Preparation

[0041] formula:

[0042] Fenji 75g Phellodendron 52.5g Qinpi 60g

[0043] Smilax 150g Alisma 112.5g Plantain 112.5g

[0044] Pittosporum peel 75g Achyranthes bidentata 75g Rhubarb 37.5g

[0045] Preparation:

[0046] Obtain clear ointment with embodiment 1 method. Take clear ointment, add appropriate amount of auxiliary materials, granulate, dry, press into 1000 tablets, coat with sugar or film coating, and get ready. Each tablet weighs 0.5g and contains not less than 2mg of berberine hydrochloride.

Embodiment 3

[0047] Embodiment 3 pill preparation

[0048] formula:

[0049]Fenji 137.5g Phellodendron 112.5g Qinpi 75g

[0050] Smilax 187.5g Alisma 125g Plantain 250g

[0051] Pittosporum peel 137.5g Achyranthes bidentata 137.5g Rhubarb 87.5g

[0052] Preparation:

[0053] Obtain clear ointment by embodiment 1 method. Take the clear paste, dry it, powder it, add 150-180g of refined honey for every 100g of powder to make big honeyed pills.

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PUM

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Abstract

The invention relates to a traditional Chinese pharmaceutical composition for treating gout and its preparing process, wherein the composition is prepared from sharpleaf galangal fruit, corktree bark, ash bark, polyporus umbellatus, oriental water plantain rhizome, plantain herb, coralbean bark, root of bidentate achyranthes, raw material and medicinal adjuvant. The composition can be prepared into various pharmaceutically acceptable oral preparations.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating gout and a preparation method thereof. Background technique [0002] Gout is a disease caused by purine metabolism disorder and continuous increase of blood uric acid due to hereditary or acquired etiology. It is a group of diseases caused by long-term purine metabolism disorder and increased blood uric acid. Clinical features include hyperuricemia, recurrent attacks of gouty acute arthritis, untimely treatment, protracted disease course, slow progression, and gout complications such as hypertension, hyperlipidemia, coronary heart disease, diabetes, and kidney stones. When the lesion is gouty nephropathy, obvious azotemia may appear, develop into renal failure and uremia, the lesion is urinary calculi, heart disease can easily lead to arteriosclerosis and coronary heart disease, which seriously threate...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/20A61P19/06
Inventor 董大伦
Owner GUIYANG XINTIAN PHARMA CO LTD
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