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Method for preparing liposome of pearl digest

A pearl hydrolyzed solution and a technology for the preparation method are applied in the directions of liposome delivery, preparations for skin care, medical preparations containing active ingredients, etc. Effect

Active Publication Date: 2006-07-05
HAINAN JINGRUN PEARL BIOTECH
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  • Summary
  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

[0003] In order to overcome the deficiency that the above-mentioned pearl hydrolyzate should not be directly added to cosmetics, the present invention provides a method for preparing pearl hydrolyzate liposomes. The pearl hydrolyzate liposomes produced by the method can reduce the conductivity of the hydrolyzate and reduce the impact on the cosmetic system. When added to cosmetics, it can also protect the active ingredients from the damage of other substances in the cosmetic system, and the pearl hydrolyzed liquid liposome can carry the active substances of pearls to the deep layer of human skin

Method used

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Embodiment Construction

[0009] a, get 2 grams of soybean lecithin, after adding 0.05 gram of propylparaben, add 10 milliliters of chloroform solution to make it dissolve completely, and make soybean lecithin dry film on a rotary evaporator;

[0010] b. Mix the disodium hydrogen phosphate solution with a concentration of 0.01 mol / ml and the sodium dihydrogen phosphate solution with a concentration of 0.01 mol / ml in a volume ratio of 61:39 to prepare 30 ml of phosphate buffer, and then hydrolyze the pearls Mix 20 ml of liquid with 30 ml of phosphate buffer, adjust its pH value to 7, then slowly add it into the bottle made of soybean lecithin dry film, carry out shaking treatment for 4 hours, and then obtain pearl hydrolyzed lipid by ultrasonic treatment plastid.

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Abstract

A lipid of the pearl-hydrolyzed liquid used for cosmetics is prepared through adding antiseptic agent to the soybean lecithin, dissolving in chloroform solution, rotational evaporating in a bottle to become the dried soybean lecithin film, dissolving the pearl-hydrolyzed liquid in the mixture of bisodium hydrogen phosphate solution and sodium bihydrogen phosphate solution, regulating pH=7, slowly pouring it into said bottle containing the dried soybean lecithin film, oscillating for 3-6 hrs, and ultrasonic treatment.

Description

technical field [0001] The invention relates to a preparation method of pearl hydrolyzate liposome. Background technique [0002] Pearl is a precious Chinese herbal medicine. It is cold in nature and sweet in taste. It has the effects of calming the nerves and calming convulsions, nourishing yin and calming wind, removing cloudiness and improving eyesight. The pearl hydrolyzate obtained by processing pearls contains glycine, alanine and cystine Such as 18 clock amino acids needed by the human body and more than 10 trace elements such as zinc, selenium, germanium, calcium, etc., and also contains soluble active protein. However, because the pearl hydrolyzate contains a variety of trace elements and has high electrical conductivity, if it is directly added to cosmetics, it is easy to destroy the stability of the cosmetic system, and it is also easy to be destroyed by other raw materials of cosmetics when pearl hydrolyzate is directly added to cosmetics. It loses its efficacy,...

Claims

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Application Information

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IPC IPC(8): A61K35/56A61K9/127A61K8/98A61Q19/00A61K35/618
Inventor 周树立
Owner HAINAN JINGRUN PEARL BIOTECH
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