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Medical film

A medical film technology, applied in medical science, textiles, fabrics, etc., can solve problems such as suturing and fixing difficulties, and achieve the effect of avoiding the reaction of tissues and foreign objects

Inactive Publication Date: 2006-01-25
GUNZE LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if this gelatin film is applied to tissues, it will become a hydrogel state containing water by absorbing the moisture of the above-mentioned tissues, so there is a problem of so-called difficulty in suture fixation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0110] Fabrication

[0111] Using lactic acid-caprolactone copolymer multifilament (thickness: 42 decitex (dtex)), a double-system braid (thickness 200 μm) with a mesh size of 3.5 mm in both the longitudinal and transverse directions and a mesh size of 3.5 mm in the longitudinal direction was produced. A double-system braid (thickness 200 μm) of 1.5 mm in both directions. Dtex (decitex: 1 decitex=1.111×denier) is an international unit of thickness. As mentioned above, Figure 7 Schematic representation of the fabric weave of the bisystem braid in . This dual-system braid was sandwiched between two glass plates, and vacuum heat-treated at 120° C. for 3 hours. Next, the heat-treated double-ring fabric body was subjected to plasma treatment under the conditions of room temperature, oxygen 67Pa (0.5 Torr), 50W, and 30 seconds.

[0112] Integration with gelatin film

[0113] The various fabric bodies obtained above were cut into rectangles of 9 cm in the longitudinal direc...

Embodiment 2

[0129] As the fabric body, a composite film was produced using a double-system knitted fabric and a warp-knitted fabric shown below, and its strength was determined. In addition, the lactic acid-caprolactone copolymer multifilament used is a lactic acid-caprolactone copolymer in which the composition ratio (molar ratio) of lactide (lactic acid dimer) and caprolactone is 75:25, It is prepared by a known method (see, for example, JP-A-08-317968).

[0130] Reinforcement material

[0131] (double system knit 2-1)

[0132] A lactic acid-caprolactone copolymer multifilament (thickness: 75 decitex (dtex)) was used to produce a double-system braided fabric having a mesh size of 2.7 mm in the longitudinal direction and 3.1 mm in the transverse direction. A photograph of the weaving structure of this double-system braid 2-1 is shown in FIG. 10(A) (25 times enlarged photograph).

[0133] (double system knit 2-2)

[0134] Using a lactic acid-caprolactone copolymer multifilament (thi...

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Abstract

It is intended to provide a medical film which is excellent in biocompatibility and bioabsorbability and has a high strength in suturing and bonding. A reinforcing material (12) made of a biodegradable and bioabsorbable polymer is located in a gelatin solution. After allowing the solution to penetrate into the reinforcing material (12), the gelatin is dried. Thus, the gelatin having penetrated into the reinforcing material (12) sets to gel to thereby form a gelatin film (11) so that a medical film (1 )composed of the reinforcing material (12) and the gelatin film (11) integrated together can be obtained. It is preferable that the above-described gelatin film (11) is a crosslinked gelatin film.

Description

technical field [0001] The present invention relates to a film for medical use, in particular, to an anti-adhesion material that is excellent in biocompatibility, bioabsorption, and suture strength, and prevents the adhesion of biological tissues to each other, and a tissue repair material or tissue repair material that supplements tissue defects. A sheet for transplanting cell cultures for transplanting sheet-like tissues in vivo. Background technique [0002] In clinical fields such as cardiac surgery, orthopedic surgery, neurosurgery, abdominal surgery, obstetrics, etc., after various surgical operations or due to trauma, adhesion (adhesion) of living tissue in diseased parts becomes a serious problem. If adhesion of tissues occurs, for example, it causes pain and dysfunction, and in severe cases, additional surgery for peeling off the above adhesion is also required. In addition, due to the adhesion, there is also a problem that reoperation for the original disease beco...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/12A61L27/44A61L27/58B32B9/02B32B27/36C08J7/00A61L31/04A61L31/14
CPCA61L31/045Y10T442/45Y10T442/674A61L31/148A61L31/129Y10T442/2525Y10T442/2861Y10T442/2484Y10T442/3854
Inventor 松田晶二郎大谷齐田中好田所英记
Owner GUNZE LTD
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